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PDB: 63 件
5U9A
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Crystal structure of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1)
分子名称: Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1)
著者Yadav, R.P, Gakhar, L, Liping, Y, Artemyev, N.O.
登録日2016-12-15
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U9J
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Crystal structure of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) complexed with geranyl geranyl pyrophoshate
分子名称: Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), GERAN-8-YL GERAN, ISOPROPYL ALCOHOL, ...
著者Yadav, R.P, Gakhar, L, Liping, Y, Artemyev, N.O.
登録日2016-12-16
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U9I
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Crystal structure of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) complexed with S-farnesyl-L-cysteine methyl ester
分子名称: Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), FARNESYL
著者Yadav, R.P, Gakhar, L, Liping, Y, Artemyev, N.O.
登録日2016-12-16
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6N84
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BU of 6n84 by Molmil
MBP-fusion protein of transducin-alpha residues 327-350
分子名称: Maltose/maltodextrin-binding periplasmic protein,Guanine nucleotide-binding protein G(t) subunit alpha-2, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Srivastava, D, Gakhar, L, Artemyev, N.O.
登録日2018-11-28
公開日2019-07-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural underpinnings of Ric8A function as a G-protein alpha-subunit chaperone and guanine-nucleotide exchange factor.
Nat Commun, 10, 2019
6N85
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Resistance to inhibitors of cholinesterase 8A (Ric8A) protein in complex with MBP-tagged transducin-alpha residues 327-350
分子名称: Maltose/maltodextrin-binding periplasmic protein,Guanine nucleotide-binding protein G(t) subunit alpha-2, Synembryn-A, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Srivastava, D, Gakhar, L, Artemyev, N.O.
登録日2018-11-28
公開日2019-07-10
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural underpinnings of Ric8A function as a G-protein alpha-subunit chaperone and guanine-nucleotide exchange factor.
Nat Commun, 10, 2019
6N86
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BU of 6n86 by Molmil
Resistance to inhibitors of cholinesterase 8A (Ric8A) protein
分子名称: Synembryn-A
著者Srivastava, D, Gakhar, L, Artemyev, N.O.
登録日2018-11-28
公開日2019-07-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural underpinnings of Ric8A function as a G-protein alpha-subunit chaperone and guanine-nucleotide exchange factor.
Nat Commun, 10, 2019
4JQW
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BU of 4jqw by Molmil
Crystal Structure of a Complex of NOD1 CARD and Ubiquitin
分子名称: Nucleotide-binding oligomerization domain-containing protein 1, PHOSPHATE ION, Polyubiquitin-C
著者Ver Heul, A.M, Gakhar, L, Piper, R.C, Ramaswamy, S.
登録日2013-03-20
公開日2014-03-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of a complex of NOD1 CARD and ubiquitin
Plos One, 9, 2014
4K2O
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The Structure of a Triple Mutant of the Tiam1 PH-CC-Ex Domain
分子名称: T-lymphoma invasion and metastasis-inducing protein 1
著者Joshi, M, Gakhar, L, Fuentes, E.J.
登録日2013-04-09
公開日2013-07-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献High-resolution structure of the Tiam1 PHn-CC-Ex domain.
Acta Crystallogr.,Sect.F, 69, 2013
4K2P
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The Structure of a Quintuple Mutant of the Tiam1 PH-CC-Ex Domain
分子名称: CALCIUM ION, T-lymphoma invasion and metastasis-inducing protein 1
著者Joshi, M, Gakhar, L, Fuentes, E.J.
登録日2013-04-09
公開日2013-07-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献High-resolution structure of the Tiam1 PHn-CC-Ex domain.
Acta Crystallogr.,Sect.F, 69, 2013
3L0X
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BU of 3l0x by Molmil
Structure of split yeast PCNA
分子名称: Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-12-10
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
3JWQ
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Crystal structure of chimeric PDE5/PDE6 catalytic domain complexed with sildenafil
分子名称: 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, MAGNESIUM ION, ZINC ION, ...
著者Barren, B, Gakhar, L, Muradov, H, Boyd, K.K, Ramaswamy, S, Artemyev, N.O.
登録日2009-09-18
公開日2009-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the gamma-subunit
Embo J., 28, 2009
3JWR
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BU of 3jwr by Molmil
Crystal structure of chimeric PDE5/PDE6 catalytic domain complexed with 3-isobutyl-1-methylxanthine (IBMX) and PDE6 gamma-subunit inhibitory peptide 70-87.
分子名称: 3-ISOBUTYL-1-METHYLXANTHINE, MAGNESIUM ION, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ...
著者Barren, B, Gakhar, L, Muradov, H, Boyd, K.K, Ramaswamy, S, Artemyev, N.O.
登録日2009-09-18
公開日2009-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.994 Å)
主引用文献Structural basis of phosphodiesterase 6 inhibition by the C-terminal region of the gamma-subunit
Embo J., 28, 2009
3L0W
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BU of 3l0w by Molmil
Structure of split monoubiquitinated PCNA with ubiquitin in position two
分子名称: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-12-10
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
3L10
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BU of 3l10 by Molmil
Structure of split monoubiquitinated PCNA with ubiquitin in position one
分子名称: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-12-10
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
4QLE
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BU of 4qle by Molmil
Crystal structure of I14A DHFR mutant complexed with folate and NADP+
分子名称: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Stojkovic, V, Gakhar, L, Kohen, A.
登録日2014-06-12
公開日2014-11-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Free energy simulations of active-site mutants of dihydrofolate reductase.
J.Phys.Chem.B, 119, 2015
4QLG
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BU of 4qlg by Molmil
Crystal structure of I14V DHFR mutant complexed with folate and NADP+
分子名称: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Stojkovic, V, Gakhar, L, Kohen, A.
登録日2014-06-12
公開日2014-11-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Free energy simulations of active-site mutants of dihydrofolate reductase.
J.Phys.Chem.B, 119, 2015
4QLF
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Crystal structure of I14G DHFR mutant complexed with folate and NADP+
分子名称: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Stojkovic, V, Gakhar, L, Kohen, A.
登録日2014-06-12
公開日2014-11-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Free energy simulations of active-site mutants of dihydrofolate reductase.
J.Phys.Chem.B, 119, 2015
7UHW
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BU of 7uhw by Molmil
Horse liver alcohol dehydrogenase G173A, complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol at 120 K
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ...
著者Plapp, B.V, Gakhar, L.
登録日2022-03-27
公開日2022-04-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Dependence of crystallographic atomic displacement factors on temperature (25-150 K) for complexes of horse liver alcohol dehydrogenases
Acta Crystallogr.,Sect.D, D78, 2022
7UHX
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Horse liver alcohol dehydrogenase G173A, complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol at 150 K
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ...
著者Plapp, B.V, Gakhar, L.
登録日2022-03-27
公開日2022-04-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Dependence of crystallographic atomic displacement factors on temperature (25-150 K) for complexes of horse liver alcohol dehydrogenases
Acta Crystallogr.,Sect.D, D78, 2022
7UHV
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Horse liver alcohol dehydrogenase G173A, complexed with NAD+ and 2,3,4,5,6-pentafluorobenzyl alcohol at 50 K
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ...
著者Plapp, B.V, Gakhar, L.
登録日2022-03-27
公開日2022-04-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Dependence of crystallographic atomic displacement factors on temperature (25-150 K) for complexes of horse liver alcohol dehydrogenases
Acta Crystallogr.,Sect.D, D78, 2022
6MYE
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BU of 6mye by Molmil
Crystal structure of human Scribble PDZ1 domain in complex with internal PDZ binding motif of Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF)
分子名称: FORMIC ACID, Protein scribble homolog, Rho guanine nucleotide exchange factor 26, ...
著者Sun, Y.J, Hou, T, Gakhar, L, Fuentes, E.J.
登録日2018-11-01
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility.
J.Cell Biol., 218, 2019
6MYF
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Crystal structure of free human Scribble PDZ1 domain
分子名称: Protein scribble homolog
著者Sun, Y.J, Hou, T, Gakhar, L, Fuentes, E.J.
登録日2018-11-01
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility.
J.Cell Biol., 218, 2019
7UCU
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Horse liver alcohol dehydrogenase with NAD and trifluoroethanol at 85K
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, Alcohol dehydrogenase E chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
著者Plapp, B.V, Gakhar, L.
登録日2022-03-17
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Dependence of crystallographic atomic displacement factors on temperature (25-150 K) for complexes of horse liver alcohol dehydrogenases
Acta Crystallogr.,Sect.D, D78, 2022
7UEC
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BU of 7uec by Molmil
Horse liver alcohol dehydrogenase with NAD and pentafluorobenzyl alcohol at 50 K
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ...
著者Plapp, B.V, Gakhar, L.
登録日2022-03-21
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Dependence of crystallographic atomic displacement factors on temperature (25-150 K) for complexes of horse liver alcohol dehydrogenases
Acta Crystallogr.,Sect.D, D78, 2022
7UEI
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Horse liver alcohol dehydrogenase with NAD and pentafluorobenzyl alcohol at 100 K, 1.2 A, crystal 16
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ...
著者Plapp, B.V, Gakhar, L.
登録日2022-03-21
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Dependence of crystallographic atomic displacement factors on temperature (25-150 K) for complexes of horse liver alcohol dehydrogenases
Acta Crystallogr.,Sect.D, D78, 2022

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