6OWO
 
 | | CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 CORE BOUND TO NECAP | | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | | Authors: | Partlow, E.A, Baker, R.W, Beacham, G.M, Chappie, J.S, Leschziner, A.E, Hollopeter, G. | | Deposit date: | 2019-05-10 | | Release date: | 2019-09-11 | | Last modified: | 2020-01-08 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex.
Elife, 8, 2019
|
|
6OQZ
 | | Crystal structure of Glucose Isomerase from Non-merohedrally twinned crystals | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, MANGANESE (II) ION, ... | | Authors: | Sevvana, M, Ruf, M, Uson, I, Sheldrick, G.M, Herbst-Irmer, R. | | Deposit date: | 2019-04-29 | | Release date: | 2019-12-11 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Non-merohedral twinning: from minerals to proteins.
Acta Crystallogr D Struct Biol, 75, 2019
|
|
6BAA
 | | Cryo-EM structure of the pancreatic beta-cell KATP channel bound to ATP and glibenclamide | | Descriptor: | 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Martin, G.M, Yoshioka, C, Shyng, S.L. | | Deposit date: | 2017-10-12 | | Release date: | 2017-11-01 | | Last modified: | 2019-12-25 | | Method: | ELECTRON MICROSCOPY (3.63 Å) | | Cite: | Anti-diabetic drug binding site in a mammalian KATPchannel revealed by Cryo-EM.
Elife, 6, 2017
|
|
6B9C
 | | Superfolder Green Fluorescent Protein with 4-nitro-L-phenylalanine at the chromophore (position 66) | | Descriptor: | CARBON DIOXIDE, Green fluorescent protein | | Authors: | Phillips-Piro, C.M, Brewer, S.H, Olenginski, G.M, Piacentini, J. | | Deposit date: | 2017-10-10 | | Release date: | 2018-10-17 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.695 Å) | | Cite: | Structural and spectrophotometric investigation of two unnatural amino-acid altered chromophores in the superfolder green fluorescent protein
Acta Crystallogr.,Sect.D, 2021
|
|
6BDO
 | |
6ARQ
 | | Crystal structure of CD96 (D1) bound to CD155/necl-5 (D1-3) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Poliovirus receptor, T-cell surface protein tactile, ... | | Authors: | Deuss, F.A, Watson, G.M, Rossjohn, J, Berry, R. | | Deposit date: | 2017-08-23 | | Release date: | 2018-11-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.88 Å) | | Cite: | Structural Basis for CD96 Immune Receptor Recognition of Nectin-like Protein-5, CD155.
Structure, 27, 2019
|
|
6PZB
 | |
6PZI
 | | Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP only | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8 | | Authors: | Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. | | Deposit date: | 2019-07-31 | | Release date: | 2019-08-14 | | Last modified: | 2020-10-07 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
|
|
6PZA
 | | Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and glibenclamide | | Descriptor: | 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. | | Deposit date: | 2019-07-31 | | Release date: | 2019-08-14 | | Last modified: | 2020-10-07 | | Method: | ELECTRON MICROSCOPY (3.74 Å) | | Cite: | Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
|
|
6BJX
 | |
6PZ9
 | | Cryo-EM structure of the pancreatic beta-cell SUR1 bound to ATP and repaglinide | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11, ... | | Authors: | Shyng, S.L, Yoshioka, C, Martin, G.M, Sung, M.W. | | Deposit date: | 2019-07-31 | | Release date: | 2019-08-14 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Mechanism of pharmacochaperoning in a mammalian K ATP channel revealed by cryo-EM.
Elife, 8, 2019
|
|
6C44
 | | Zika virus capsid protein | | Descriptor: | Capsid protein | | Authors: | Morando, M.A, Barbosa, G.M, Cruz-Oliveira, C, Da Poian, A.T, Almeida, F.C.L. | | Deposit date: | 2018-01-11 | | Release date: | 2019-01-16 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Dynamics of Zika Virus Capsid Protein in Solution: The Properties and Exposure of the Hydrophobic Cleft Are Controlled by the alpha-Helix 1 Sequence.
Biochemistry, 58, 2019
|
|
6PZC
 | |
6D8M
 | |
6N8C
 | | Structure of the Huntingtin tetramer/dimer mixture determined by paramagnetic NMR | | Descriptor: | Huntingtin | | Authors: | Schwieters, C.D, Kotler, S.A, Schmidt, T, Ceccon, A, Ghirlando, R, Libich, D.S, Clore, G.M. | | Deposit date: | 2018-11-29 | | Release date: | 2019-02-13 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
3EZB
 | | COMPLEX OF THE AMINO TERMINAL DOMAIN OF ENZYME I AND THE HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR FROM ESCHERICHIA COLI | | Descriptor: | PROTEIN (PHOSPHOCARRIER PROTEIN HPR), PROTEIN (PHOSPHOTRANSFER SYSTEM, ENZYME I) | | Authors: | Clore, G.M, Garrett, D.S, Gronenborn, A.M. | | Deposit date: | 1998-11-03 | | Release date: | 1999-12-16 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.
Nat.Struct.Biol., 6, 1999
|
|
3EZE
 | | COMPLEX OF THE AMINO TERMINAL DOMAIN OF ENZYME I AND THE HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR FROM ESCHERICHIA COLI NMR, RESTRAINED REGULARIZED MEAN STRUCTURE | | Descriptor: | PHOSPHITE ION, PROTEIN (PHOSPHOTRANSFERASE SYSTEM, ENZYME I), ... | | Authors: | Clore, G.M, Garrett, D.S, Gronenborn, A.M. | | Deposit date: | 1998-11-04 | | Release date: | 1998-12-16 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.
Nat.Struct.Biol., 6, 1999
|
|
3EZA
 | | COMPLEX OF THE AMINO TERMINAL DOMAIN OF ENZYME I AND THE HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR FROM ESCHERICHIA COLI NMR, RESTRAINED REGULARIZED MEAN STRUCTURE | | Descriptor: | HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR, PHOSPHOTRANSFERASE SYSTEM, ENZYME I | | Authors: | Clore, G.M, Garrett, D.S, Gronenborn, A.M. | | Deposit date: | 1998-11-03 | | Release date: | 1999-05-25 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the 40,000 Mr phosphoryl transfer complex between the N-terminal domain of enzyme I and HPr.
Nat.Struct.Biol., 6, 1999
|
|
7P9D
 | | Crystal structure of Chlamydomonas reinhardtii NADPH Dependent Thioredoxin Reductase 1 domain | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase | | Authors: | Singh, R.K, Marchetti, G.M, Hippler, M, Kuemmel, D. | | Deposit date: | 2021-07-27 | | Release date: | 2022-01-12 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Structural analysis revealed a novel conformation of the NTRC reductase domain from Chlamydomonas reinhardtii.
J.Struct.Biol., 214, 2021
|
|
7P49
 | | HLA-E*01:03 in complex with Mtb14 | | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | Authors: | Walters, L.C, Gillespie, G.M. | | Deposit date: | 2021-07-10 | | Release date: | 2022-06-22 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
Cell Rep, 39, 2022
|
|
7P4B
 | | HLA-E*01:03 in complex with IL9 | | Descriptor: | Beta-2-microglobulin, ESAT-6-like protein EsxH, GLYCEROL, ... | | Authors: | Walters, L.C, Gillespie, G.M. | | Deposit date: | 2021-07-10 | | Release date: | 2022-07-27 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Primary and secondary functions of HLA-E are determined by stability and conformation of the peptide-bound complexes.
Cell Rep, 39, 2022
|
|
3IF6
 | | Crystal structure of OXA-46 beta-lactamase from P. aeruginosa | | Descriptor: | 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, L(+)-TARTARIC ACID, ... | | Authors: | Docquier, J.D, Benvenuti, M, Calderone, V, Giuliani, F, Kapetis, D, De Luca, F, Rossolini, G.M, Mangani, S. | | Deposit date: | 2009-07-24 | | Release date: | 2010-03-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the narrow-spectrum OXA-46 class D beta-lactamase: relationship between active-site lysine carbamylation and inhibition by polycarboxylates
Antimicrob.Agents Chemother., 54, 2010
|
|
7PPZ
 | | Crystal structure of the Burkholderia Lethal Factor 1 (BLF1) C94S inactive mutant in complex with human eIF4A - Crystal form A | | Descriptor: | Burkholderia Lethal Factor 1 (BLF1), Eukaryotic initiation factor 4A-I | | Authors: | Mobbs, G.W, Aziz, A.A, Dix, S.R, Blackburn, G.M, Sedelnikova, S.E, Minshull, T.C, Dickman, M.J, Baker, P.J, Nathan, S, Firdaus-Raih, M, Rice, D.W. | | Deposit date: | 2021-09-15 | | Release date: | 2022-04-13 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.52 Å) | | Cite: | Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1.
Commun Biol, 5, 2022
|
|
7PQ0
 | | Crystal structure of the Burkholderia Lethal Factor 1 (BLF1) C94S inactive mutant in complex with human eIF4A - Crystal form B | | Descriptor: | Burkholderia Lethal Factor 1 (BLF1), Eukaryotic initiation factor 4A-I | | Authors: | Mobbs, G.W, Aziz, A.A, Dix, S.R, Blackburn, G.M, Sedelnikova, S.E, Minshull, T.C, Dickman, M.J, Baker, P.J, Nathan, S, Firdaus-Raih, M, Rice, D.W. | | Deposit date: | 2021-09-15 | | Release date: | 2022-04-13 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Molecular basis of specificity and deamidation of eIF4A by Burkholderia Lethal Factor 1.
Commun Biol, 5, 2022
|
|
7R94
 | | T-Plastin-F-actin complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Mei, L, Alushin, G.M. | | Deposit date: | 2021-06-28 | | Release date: | 2022-07-06 | | Last modified: | 2022-09-21 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
