Structure of bacterial type II NADH dehydrogenase from Caldalkalibacillus thermarum complexed with a quinone inhibitor HQNO at 2.8A resolution

Summary for 6BDO

Related4NWZ 5WED
DescriptorFAD-dependent pyridine nucleotide-disulfide oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE, 2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE, ... (4 entities in total)
Functional Keywordsrossmann fold, nadh dehydrogenase, oxidoreductase, flavo protein, membrane protein, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
Biological sourceCaldalkalibacillus thermarum TA2.A1
Total number of polymer chains4
Total molecular weight181948.84
Cook, G.M.,Aragao, D.,Nakatani, Y. (deposition date: 2017-10-23, release date: 2018-05-16, Last modification date: 2020-01-01)
Primary citation
Petri, J.,Shimaki, Y.,Jiao, W.,Bridges, H.R.,Russell, E.R.,Parker, E.J.,Aragao, D.,Cook, G.M.,Nakatani, Y.
Structure of the NDH-2 - HQNO inhibited complex provides molecular insight into quinone-binding site inhibitors.
Biochim. Biophys. Acta, 1859:482-490, 2018
PubMed: 29621505 (PDB entries with the same primary citation)
DOI: 10.1016/j.bbabio.2018.03.014
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27140.2%1.9%3.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-08-05