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PDB: 129 件
1IVS
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BU of 1ivs by Molmil
CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS VALYL-TRNA SYNTHETASE COMPLEXED WITH TRNA(VAL) AND VALYL-ADENYLATE ANALOGUE
分子名称: N-[VALINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, Valyl-tRNA synthetase, tRNA (Val)
著者Fukai, S, Nureki, O, Sekine, S.-I, Shimada, A, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-03-29
公開日2003-02-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase
RNA, 9, 2003
1GAX
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BU of 1gax by Molmil
CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS VALYL-TRNA SYNTHETASE COMPLEXED WITH TRNA(VAL) AND VALYL-ADENYLATE ANALOGUE
分子名称: N-[VALINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, TRNA(VAL), VALYL-TRNA SYNTHETASE, ...
著者Fukai, S, Nureki, O, Sekine, S, Shimada, A, Tao, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2000-06-23
公開日2000-12-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase.
Cell(Cambridge,Mass.), 103, 2000
1IYW
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BU of 1iyw by Molmil
Preliminary Structure of Thermus thermophilus Ligand-Free Valyl-tRNA Synthetase
分子名称: Valyl-tRNA Synthetase
著者Fukai, S, Nureki, O, Sekine, S, Shimada, A, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-09-10
公開日2003-06-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase
RNA, 9, 2003
1UAD
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BU of 1uad by Molmil
Crystal structure of the RalA-GppNHp-Sec5 Ral-binding domain complex
分子名称: Exocyst complex component Sec5, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Fukai, S, Matern, H.T, Scheller, R.H, Brunger, A.T.
登録日2003-03-09
公開日2003-07-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of the interaction between RalA and Sec5, a subunit of the Sec6/8 complex
EMBO J., 22, 2003
2E7S
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BU of 2e7s by Molmil
Crystal structure of the yeast Sec2p GEF domain
分子名称: Rab guanine nucleotide exchange factor SEC2
著者Fukai, S, Sato, Y, Nureki, O.
登録日2007-01-12
公開日2007-02-27
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Asymmetric Coiled-Coil Structure with Guanine Nucleotide Exchange Activity
Structure, 15, 2007
4UBQ
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BU of 4ubq by Molmil
Crystal Structure of IMP-2 Metallo-beta-Lactamase from Acinetobacter spp.
分子名称: ACETATE ION, Beta-lactamase, ZINC ION
著者Yamaguchi, Y, Matsueda, S, Matsunaga, K, Takashio, N, Toma-Fukai, S, Yamagata, Y, Shibata, N, Wachino, J, Shibayama, K, Arakawa, Y, Kurosaki, H.
登録日2014-08-13
公開日2014-12-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of IMP-2 metallo-beta-lactamase from Acinetobacter spp.: comparison of active-site loop structures between IMP-1 and IMP-2.
Biol.Pharm.Bull., 38, 2015
8J6N
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BU of 8j6n by Molmil
Crystal structure of Cystathionine gamma-lyase in complex with compound 1
分子名称: 1,2-ETHANEDIOL, Cystathionine gamma-lyase, GLYCEROL, ...
著者Hibi, R, Toma-Fukai, S, Shimizu, T, Hanaoka, K.
登録日2023-04-26
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of a cystathionine gamma-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5'-phosphate (PLP) via Schiff base formation.
Sci Rep, 13, 2023
5WQJ
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BU of 5wqj by Molmil
Crystal structure of 3-Mercaptopyruvate Sulfurtransferase(3MST) in complex with compound1
分子名称: 2-[2-[(4-oxidanylidene-3~{H}-quinazolin-2-yl)sulfanyl]ethanoylamino]thiophene-3-carboxamide, SODIUM ION, Sulfurtransferase
著者Suwanai, Y, Toma-Fukai, S, Shimizu, T.
登録日2016-11-27
公開日2017-09-06
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide
Sci Rep, 7, 2017
3JSV
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BU of 3jsv by Molmil
Crystal structure of mouse NEMO CoZi in complex with Lys63-linked di-ubiquitin
分子名称: NF-kappa-B essential modulator, Ubiquitin
著者Yoshikawa, A, Sato, Y, Mimura, H, Yamashita, M, Yamagata, A, Fukai, S.
登録日2009-09-11
公開日2009-10-27
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin
Febs Lett., 583, 2009
1KN0
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Crystal Structure of the human Rad52 protein
分子名称: Rad52
著者Kagawa, W, Kurumizaka, H, Ishitani, R, Fukai, S, Nureki, O, Shibata, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2001-12-18
公開日2002-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form.
Mol.Cell, 10, 2002
7CEE
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BU of 7cee by Molmil
Crystal structure of mouse neuroligin-3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroligin-3
著者Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S.
登録日2020-06-23
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.763 Å)
主引用文献Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Nat Commun, 12, 2021
7CEG
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Crystal structure of the complex between mouse PTP delta and neuroligin-3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform C of Receptor-type tyrosine-protein phosphatase delta, Neuroligin-3
著者Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S.
登録日2020-06-23
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.85 Å)
主引用文献Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Nat Commun, 12, 2021
5B86
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BU of 5b86 by Molmil
Crystal structure of M-Sec
分子名称: Tumor necrosis factor alpha-induced protein 2
著者Yamashita, M, Sato, Y, Yamagata, A, Fukai, S.
登録日2016-06-12
公開日2016-10-12
最終更新日2020-02-26
実験手法X-RAY DIFFRACTION (3.017 Å)
主引用文献Distinct Roles for the N- and C-terminal Regions of M-Sec in Plasma Membrane Deformation during Tunneling Nanotube Formation.
Sci Rep, 6, 2016
5DST
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BU of 5dst by Molmil
Crystal structure of human PRMT8 in complex with SAH
分子名称: Protein arginine N-methyltransferase 8, S-ADENOSYL-L-HOMOCYSTEINE
著者Toma-Fukai, S, Shimizu, T.
登録日2015-09-17
公開日2016-02-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.963 Å)
主引用文献Novel helical assembly in arginine methyltransferase 8
J.Mol.Biol., 428, 2016
1VFG
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BU of 1vfg by Molmil
Crystal structure of tRNA nucleotidyltransferase complexed with a primer tRNA and an incoming ATP analog
分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, RNA (75-MER), poly A polymerase
著者Tomita, K, Fukai, S, Ishitani, R, Ueda, T, Takeuchi, N, Vassylyev, D.G, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-04-13
公開日2004-08-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for template-independent RNA polymerization.
Nature, 430, 2004
1WY5
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BU of 1wy5 by Molmil
Crystal structure of isoluecyl-tRNA lysidine synthetase
分子名称: Hypothetical UPF0072 protein AQ_1887
著者Nakanishi, K, Fukai, S, Ikeuchi, Y, Soma, A, Sekine, Y, Suzuki, T, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-02-06
公開日2005-05-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain.
Proc.Natl.Acad.Sci.Usa, 102, 2005
4YH7
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BU of 4yh7 by Molmil
Crystal structure of PTPdelta ectodomain in complex with IL1RAPL1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein-like 1, ...
著者Yamagata, A, Fukai, S.
登録日2015-02-27
公開日2015-05-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (4.4 Å)
主引用文献Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
4YFE
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Crystal structure of PTP delta Fn1-Fn2
分子名称: Receptor-type tyrosine-protein phosphatase delta
著者Yamagata, A, Fukai, S.
登録日2015-02-25
公開日2015-05-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.972 Å)
主引用文献Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
4YFG
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Crystal structure of PTP delta meA3/meB minus variant Ig1-Fn1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase delta
著者Yamagata, A, Fukai, S.
登録日2015-02-25
公開日2015-05-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.491 Å)
主引用文献Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
4YH6
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Crystal structure of IL1RAPL1 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein-like 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yamagata, A, Fukai, S.
登録日2015-02-27
公開日2015-05-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
4YFD
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Crystal structure PTP delta Ig1-Fn2 in complex with IL-1RAcP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein, Receptor-type tyrosine-protein phosphatase delta
著者Yamagata, A, Fukai, S.
登録日2015-02-25
公開日2015-05-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.253 Å)
主引用文献Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
7BY1
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BU of 7by1 by Molmil
Crystal structure of GCN5 PCAF N-terminal domain
分子名称: Histone acetyltransferase KAT2A, ZINC ION
著者Hibi, R, Toma-Fukai, S, Shimizu, T.
登録日2020-04-21
公開日2020-08-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of GCN5 PCAF N-terminal domain reveals atypical ubiquitin ligase structure.
J.Biol.Chem., 295, 2020
7CQF
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Crystal structure of PSD-95 PDZ3 fused with ADAM22 C-terminal peptide
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CHOLINE ION, ...
著者Yamagata, A, Fukai, S.
登録日2020-08-10
公開日2021-01-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献LGI1-ADAM22-MAGUK configures transsynaptic nanoalignment for synaptic transmission and epilepsy prevention.
Proc.Natl.Acad.Sci.USA, 118, 2021
7E62
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Mouse TAB2 NZF in complex with Lys6-linked diubiquitin
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TGF-beta-activated kinase 1 and MAP3K7-binding protein 2, Ubiquitin, ...
著者Sato, Y, Li, Y, Okatsu, K, Fukai, S.
登録日2021-02-21
公開日2021-08-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural basis for specific recognition of K6-linked polyubiquitin chains by the TAB2 NZF domain.
Biophys.J., 120, 2021
7EXE
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Crystal structure of mouse 14-3-3zeta in complex with doubly phosphorylated ADAM22 peptide
分子名称: 14-3-3 protein zeta/delta, Disintegrin and metalloproteinase domain-containing protein 22
著者Yan, L, Okatsu, K, Fukai, S.
登録日2021-05-27
公開日2021-11-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献LGI1-ADAM22 levels regulate seizure thresholds through 14-3-3 in mice
Cell Rep, 2021

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