4PJ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pj1 by Molmil](/molmil-images/mine/4pj1) | Crystal structure of the human mitochondrial chaperonin symmetrical 'football' complex | Descriptor: | 10 kDa heat shock protein, mitochondrial, 60 kDa heat shock protein, ... | Authors: | Frolow, F, Azem, A, Nisemblat, S. | Deposit date: | 2014-05-10 | Release date: | 2015-04-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Crystal structure of the human mitochondrial chaperonin symmetrical football complex. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
4N2O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4n2o by Molmil](/molmil-images/mine/4n2o) | Structure of a novel autonomous cohesin protein from Ruminococcus flavefaciens | Descriptor: | Autonomous cohesin, CHLORIDE ION | Authors: | Frolow, F, Voronov-Goldman, M, Levy-Assaraf, M, Lamed, R, Bayer, E, Shimon, L. | Deposit date: | 2013-10-05 | Release date: | 2013-12-18 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.442 Å) | Cite: | Structural characterization of a novel autonomous cohesin from Ruminococcus flavefaciens. Acta Crystallogr F Struct Biol Commun, 70, 2014
|
|
2OUI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2oui by Molmil](/molmil-images/mine/2oui) | D275P mutant of alcohol dehydrogenase from protozoa Entamoeba histolytica | Descriptor: | 1,2-ETHANEDIOL, CACODYLATE ION, CHLORIDE ION, ... | Authors: | Frolow, F, Shimon, L, Burstein, Y, Goihberg, E, Peretz, M, Dym, O. | Deposit date: | 2007-02-11 | Release date: | 2008-02-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution. Proteins, 72, 2008
|
|
1BCF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bcf by Molmil](/molmil-images/mine/1bcf) | THE STRUCTURE OF A UNIQUE, TWO-FOLD SYMMETRIC, HAEM-BINDING SITE | Descriptor: | BACTERIOFERRITIN, MANGANESE (II) ION, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Frolow, F, Kalb(Gilboa), A.J, Yariv, J. | Deposit date: | 1993-12-06 | Release date: | 1994-12-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of a unique twofold symmetric haem-binding site. Nat.Struct.Biol., 1, 1994
|
|
2ZF9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zf9 by Molmil](/molmil-images/mine/2zf9) | |
2YEO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2yeo by Molmil](/molmil-images/mine/2yeo) | A39L mutation of scorpion toxin lqh-alpha-it | Descriptor: | 1,2-ETHANEDIOL, ALPHA-INSECT TOXIN LQHAIT, CHLORIDE ION, ... | Authors: | Frolow, F, Kahn, R, Gurevitz, M. | Deposit date: | 2011-03-28 | Release date: | 2011-04-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Crystal Structures of Scorpion Alpha-Toxinsmutants Reveal Conformational Constraints that Dictate Preference for Mammalian Brain Voltage-Gated Na- Channels To be Published
|
|
4EYZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4eyz by Molmil](/molmil-images/mine/4eyz) | Crystal structure of an uncommon cellulosome-related protein module from Ruminococcus flavefaciens that resembles papain-like cysteine peptidases | Descriptor: | 1,2-ETHANEDIOL, Cellulosome-related protein module from Ruminococcus flavefaciens that resembles papain-like cysteine peptidases | Authors: | Frolow, F, Voronov-Goldman, M, Bayer, E, Lamed, R. | Deposit date: | 2012-05-02 | Release date: | 2013-03-20 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.383 Å) | Cite: | Crystal Structure of an Uncommon Cellulosome-Related Protein Module from Ruminococcus flavefaciens That Resembles Papain-Like Cysteine Peptidases. Plos One, 8, 2013
|
|
2I61
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2i61 by Molmil](/molmil-images/mine/2i61) | Depressant anti-insect neurotoxin, LqhIT2 from Leiurus quinquestriatus hebraeus | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, CARBON DIOXIDE, ... | Authors: | Frolow, F, Gurevitz, M, Karbat, I, Turkov, M, Gordon, D. | Deposit date: | 2006-08-27 | Release date: | 2006-12-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | X-ray Structure and Mutagenesis of the Scorpion Depressant Toxin LqhIT2 Reveals Key Determinants Crucial for Activity and Anti-Insect Selectivity. J.Mol.Biol., 366, 2007
|
|
2HU3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hu3 by Molmil](/molmil-images/mine/2hu3) | Parent Structure of Hen Egg White Lysozyme grown in acidic pH 4.8. Refinement for comparison with crosslinked molecules of lysozyme | Descriptor: | 1,2-ETHANEDIOL, AMMONIUM ION, CHLORIDE ION, ... | Authors: | Frolow, F, Lagziel-Simis, S, Cohen-Hadar, N, Wine, Y, Freeman, A. | Deposit date: | 2006-07-26 | Release date: | 2007-07-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Monitoring influence of pH on the molecular and crystal structure of hen egg-white tetragonal lysozyme To be Published
|
|
2HUB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hub by Molmil](/molmil-images/mine/2hub) | Structure of Hen Egg-White Lysozyme Determined from crystals grown in pH 7.5 | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, D(-)-TARTARIC ACID, ... | Authors: | Frolow, F, Lagziel-Simis, S, Cohen-Hadar, N, Wine, Y, Freeman, A. | Deposit date: | 2006-07-26 | Release date: | 2007-07-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.201 Å) | Cite: | Monitoring influence of pH on the molecular and crystal structure of hen egg-white tetragonal lysozyme To be Published
|
|
3FSR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fsr by Molmil](/molmil-images/mine/3fsr) | Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-295 of T. brockii ADH by C. beijerinckii ADH | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, NADP-dependent alcohol dehydrogenase, ... | Authors: | Frolow, F, Greenblatt, H, Goihberg, E, Burstein, Y. | Deposit date: | 2009-01-11 | Release date: | 2010-01-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms Biochemistry, 49, 2010
|
|
3FTN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ftn by Molmil](/molmil-images/mine/3ftn) | Q165E/S254K Double Mutant Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-295 of T. brockii ADH by C. beijerinckii ADH | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Frolow, F, Goihberg, E, Shimon, L, Burstein, Y. | Deposit date: | 2009-01-13 | Release date: | 2010-01-26 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.192 Å) | Cite: | Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms. Biochemistry, 49, 2010
|
|
1DOI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1doi by Molmil](/molmil-images/mine/1doi) | 2FE-2S FERREDOXIN FROM HALOARCULA MARISMORTUI | Descriptor: | 2FE-2S FERREDOXIN, FE2/S2 (INORGANIC) CLUSTER, POTASSIUM ION | Authors: | Frolow, F, Harel, M, Sussman, J.L, Shoham, M. | Deposit date: | 1996-04-08 | Release date: | 1996-08-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Insights into protein adaptation to a saturated salt environment from the crystal structure of a halophilic 2Fe-2S ferredoxin. Nat.Struct.Biol., 3, 1996
|
|
3F2L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f2l by Molmil](/molmil-images/mine/3f2l) | Crystal structure analysis of the K171A mutation of N-terminal type II cohesin 1 from the cellulosomal ScaB subunit of Acetivibrio cellulolyticus | Descriptor: | 1,2-ETHANEDIOL, AMMONIUM ION, Cellulosomal scaffoldin adaptor protein B, ... | Authors: | Frolow, F, Freeman, A, Wine, Y, Eppel, A, Shanzer, M, Stempler, S. | Deposit date: | 2008-10-30 | Release date: | 2008-12-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure analysis of the K171A mutation of N-terminal type II cohesin 1 from the cellulosomal ScaB subunit of Acetivibrio cellulolyticus To be Published
|
|
1QZN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1qzn by Molmil](/molmil-images/mine/1qzn) | Crystal Structure Analysis of a type II cohesin domain from the cellulosome of Acetivibrio cellulolyticus | Descriptor: | cellulosomal scaffoldin adaptor protein B | Authors: | Frolow, F, Noach, I, Rosenheck, S, Lamed, R, Qi, X, Shimon, L.J.W, Bayer, E.A. | Deposit date: | 2003-09-17 | Release date: | 2004-09-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of a type-II cohesin module from the Bacteroides cellulosolvens cellulosome reveals novel and distinctive secondary structural elements. J.Mol.Biol., 348, 2005
|
|
3BWZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bwz by Molmil](/molmil-images/mine/3bwz) | Crystal structure of the type II cohesin module from the cellulosome of Acetivibrio cellulolyticus with an extended linker conformation | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Cellulosomal scaffoldin adaptor protein B, ... | Authors: | Noach, I, Lamed, R, Shimon, L.J.W, Bayer, E, Frolow, F. | Deposit date: | 2008-01-10 | Release date: | 2009-01-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Intermodular linker flexibility revealed from crystal structures of adjacent cellulosomal cohesins of Acetivibrio cellulolyticus. J.Mol.Biol., 391, 2009
|
|
1VT9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vt9 by Molmil](/molmil-images/mine/1vt9) | |
1VT8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vt8 by Molmil](/molmil-images/mine/1vt8) | Crystal structure of D(GGGCGCCC)-hexagonal form | Descriptor: | DNA (5'-D(*GP*GP*GP*CP*GP*CP*CP*C)-3') | Authors: | Shakked, Z, Guerstein-Guzikevich, G, Eisenstein, M, Frolow, F, Rabinovich, D. | Deposit date: | 1996-12-02 | Release date: | 2011-07-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The conformation of the DNA double helix in the crystal is dependent on its environment. Nature, 342, 1989
|
|
3L8Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3l8q by Molmil](/molmil-images/mine/3l8q) | Structure analysis of the type II cohesin dyad from the adaptor ScaA scaffoldin of Acetivibrio cellulolyticus | Descriptor: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, Cellulosomal scaffoldin adaptor protein B, ... | Authors: | Noach, I, Frolow, F, Bayer, E.A. | Deposit date: | 2010-01-03 | Release date: | 2010-05-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Modular Arrangement of a Cellulosomal Scaffoldin Subunit Revealed from the Crystal Structure of a Cohesin Dyad J.Mol.Biol., 399, 2010
|
|
3D08
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d08 by Molmil](/molmil-images/mine/3d08) | Human p53 core domain with hot spot mutation R249S and second-site suppressor mutation H168R | Descriptor: | Cellular tumor antigen p53, ZINC ION | Authors: | Suad, O, Rozenberg, H, Shimon, L.J.W, Frolow, F, Shakked, Z. | Deposit date: | 2008-05-01 | Release date: | 2009-01-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations J.Mol.Biol., 385, 2009
|
|
3D06
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d06 by Molmil](/molmil-images/mine/3d06) | Human p53 core domain with hot spot mutation R249S (I) | Descriptor: | Cellular tumor antigen p53, ZINC ION | Authors: | Rozenberg, H, Suad, O, Shimon, L.J.W, Frolow, F, Shakked, Z. | Deposit date: | 2008-05-01 | Release date: | 2009-01-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations J.Mol.Biol., 385, 2009
|
|
7KCI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7kci by Molmil](/molmil-images/mine/7kci) | DETERMINANTS OF REPRESSOR/OPERATOR RECOGNITION FROM THE STRUCTURE OF THE TRP OPERATOR BINDING SITE | Descriptor: | Self-complementary deoxyoligonucleotide decamer d(CCACTAGTGG) | Authors: | Shakked, Z, Guzikevich-Guerstein, G, Frolow, F, Rabinovich, D, Joachimiak, A, Sigler, P.B. | Deposit date: | 1994-09-12 | Release date: | 2020-10-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Determinants of repressor/operator recognition from the structure of the trp operator binding site. Nature, 368, 1994
|
|
2NVB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2nvb by Molmil](/molmil-images/mine/2nvb) | Contribution of Pro275 to the Thermostability of the Alcohol Dehydrogenases (ADHs) | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent alcohol dehydrogenase, ZINC ION | Authors: | Goihberg, E, Tel-Or, S, Peretz, M, Frolow, F, Dym, O, Burstein, Y, Israel Structural Proteomics Center (ISPC) | Deposit date: | 2006-11-12 | Release date: | 2007-11-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution Proteins, 72, 2008
|
|
6ZOI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zoi by Molmil](/molmil-images/mine/6zoi) | A lid blocking mechanism of a cone snail toxin revealed at the atomic level | Descriptor: | Conknunitzin-C3 mutante | Authors: | Saikia, C, Altman-Gueta, H, Dym, O, Frolow, F, Gurevitz, M, Gordon, D, Reuveny, E, Karbat, I. | Deposit date: | 2020-07-07 | Release date: | 2021-07-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | A lid blocking mechanism of a cone snail toxin revealed at the atomic level To Be Published
|
|
1PED
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ped by Molmil](/molmil-images/mine/1ped) | BACTERIAL SECONDARY ALCOHOL DEHYDROGENASE (APO-FORM) | Descriptor: | NADP-DEPENDENT ALCOHOL DEHYDROGENASE, ZINC ION | Authors: | Korkhin, Y, Frolow, F. | Deposit date: | 1995-12-28 | Release date: | 1997-07-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystalline alcohol dehydrogenases from the mesophilic bacterium Clostridium beijerinckii and the thermophilic bacterium Thermoanaerobium brockii: preparation, characterization and molecular symmetry. Acta Crystallogr.,Sect.D, 52, 1996
|
|