3FTN
Q165E/S254K Double Mutant Chimera of alcohol dehydrogenase by exchange of the cofactor binding domain res 153-295 of T. brockii ADH by C. beijerinckii ADH
Summary for 3FTN
Entry DOI | 10.2210/pdb3ftn/pdb |
Descriptor | NADP-dependent alcohol dehydrogenase, ZINC ION, ACETATE ION, ... (6 entities in total) |
Functional Keywords | oxydoreductase, bacterial alcohol dehydrogenase, domain exchange, chimera, metal-binding, nadp, oxidoreductase, zinc |
Biological source | Thermoanaerobacter brockii More |
Total number of polymer chains | 4 |
Total formula weight | 152810.06 |
Authors | Frolow, F.,Goihberg, E.,Shimon, L.,Burstein, Y. (deposition date: 2009-01-13, release date: 2010-01-26, Last modification date: 2024-02-21) |
Primary citation | Goihberg, E.,Peretz, M.,Tel-Or, S.,Dym, O.,Shimon, L.,Frolow, F.,Burstein, Y. Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms. Biochemistry, 49:1943-1953, 2010 Cited by PubMed: 20102159DOI: 10.1021/bi901730x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.192 Å) |
Structure validation
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