3PGE
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![BU of 3pge by Molmil](/molmil-images/mine/3pge) | Structure of sumoylated PCNA | 分子名称: | Proliferating cell nuclear antigen, SUMO-modified proliferating cell nuclear antigen | 著者 | Freudenthal, B.D, Brogie, J.E, Gakhar, L, Washington, T. | 登録日 | 2010-11-01 | 公開日 | 2010-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of SUMO-Modified Proliferating Cell Nuclear Antigen. J.Mol.Biol., 406, 2011
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5DG0
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![BU of 5dg0 by Molmil](/molmil-images/mine/5dg0) | |
5DFI
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![BU of 5dfi by Molmil](/molmil-images/mine/5dfi) | |
6DIA
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![BU of 6dia by Molmil](/molmil-images/mine/6dia) | DNA polymerase beta substrate complex with templating cytosine and incoming Fapy-dGTP analog | 分子名称: | 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol, CALCIUM ION, DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | 著者 | Freudenthal, B.D, Smith, M.R, Wilson, S.H, Beard, W.A. | 登録日 | 2018-05-23 | 公開日 | 2019-01-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.969 Å) | 主引用文献 | A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition. Nucleic Acids Res., 47, 2019
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6DIC
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![BU of 6dic by Molmil](/molmil-images/mine/6dic) | D276G DNA polymerase beta substrate complex with templating cytosine and incoming Fapy-dGTP analog | 分子名称: | 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol, CALCIUM ION, CHLORIDE ION, ... | 著者 | Freudenthal, B.D, Smith, M.R, Wilson, S.H, Beard, W.A. | 登録日 | 2018-05-23 | 公開日 | 2019-01-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.992 Å) | 主引用文献 | A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition. Nucleic Acids Res., 47, 2019
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6MR8
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![BU of 6mr8 by Molmil](/molmil-images/mine/6mr8) | D276G DNA polymerase beta substrate complex with templating adenine and incoming Fapy-dGTP analog | 分子名称: | 1,2-ETHANEDIOL, 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol, CALCIUM ION, ... | 著者 | Freudenthal, B.D, Smith, M.R, Wilson, S.H, Beard, W.A. | 登録日 | 2018-10-11 | 公開日 | 2019-01-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.897 Å) | 主引用文献 | A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition. Nucleic Acids Res., 47, 2019
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6MR7
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![BU of 6mr7 by Molmil](/molmil-images/mine/6mr7) | DNA polymerase beta substrate complex with templating adenine and incoming Fapy-dGTP analog | 分子名称: | 1,2-ETHANEDIOL, 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol, CALCIUM ION, ... | 著者 | Freudenthal, B.D, Smith, M.R, Wilson, S.H, Beard, W.A. | 登録日 | 2018-10-11 | 公開日 | 2019-01-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.144 Å) | 主引用文献 | A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition. Nucleic Acids Res., 47, 2019
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5DFF
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![BU of 5dff by Molmil](/molmil-images/mine/5dff) | Human APE1 product complex | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Freudenthal, B.D, Wilson, S.H. | 登録日 | 2015-08-26 | 公開日 | 2015-10-14 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Capturing snapshots of APE1 processing DNA damage. Nat.Struct.Mol.Biol., 22, 2015
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5DFH
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![BU of 5dfh by Molmil](/molmil-images/mine/5dfh) | Human APE1 mismatch product complex | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | 著者 | Freudenthal, B.D, Wilson, S.H. | 登録日 | 2015-08-26 | 公開日 | 2015-10-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | 主引用文献 | Capturing snapshots of APE1 processing DNA damage. Nat.Struct.Mol.Biol., 22, 2015
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5DFJ
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5BOL
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![BU of 5bol by Molmil](/molmil-images/mine/5bol) | DNA polymerase beta ternary complex with a templating 5ClC and incoming dGTP analog | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*(CDO)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... | 著者 | Freudenthal, B.D, Wilson, S.H. | 登録日 | 2015-05-27 | 公開日 | 2015-08-19 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | 主引用文献 | Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer. Proc.Natl.Acad.Sci.USA, 112, 2015
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5BPC
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![BU of 5bpc by Molmil](/molmil-images/mine/5bpc) | |
5BOM
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![BU of 5bom by Molmil](/molmil-images/mine/5bom) | DNA polymerase beta binary complex with a templating 5ClC | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*CP*(4U3)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | 著者 | Freudenthal, B.D, Wilson, S.H. | 登録日 | 2015-05-27 | 公開日 | 2015-08-19 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.0002 Å) | 主引用文献 | Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer. Proc.Natl.Acad.Sci.USA, 112, 2015
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3F1W
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![BU of 3f1w by Molmil](/molmil-images/mine/3f1w) | |
3GPM
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![BU of 3gpm by Molmil](/molmil-images/mine/3gpm) | Structure of the trimeric form of the E113G PCNA mutant protein | 分子名称: | Proliferating cell nuclear antigen | 著者 | Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. | 登録日 | 2009-03-23 | 公開日 | 2009-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions. Acta Crystallogr.,Sect.D, 65, 2009
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3GPN
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![BU of 3gpn by Molmil](/molmil-images/mine/3gpn) | Structure of the non-trimeric form of the E113G PCNA mutant protein | 分子名称: | Proliferating cell nuclear antigen | 著者 | Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. | 登録日 | 2009-03-23 | 公開日 | 2009-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions. Acta Crystallogr.,Sect.D, 65, 2009
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7TR7
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![BU of 7tr7 by Molmil](/molmil-images/mine/7tr7) | APE1 product complex with abasic ssDNA | 分子名称: | DNA (5'-D(P*(3DR)P*CP*GP*AP*TP*GP*C)-3'), DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION | 著者 | Freudenthal, B.D, Hoitsma, N.M. | 登録日 | 2022-01-28 | 公開日 | 2023-04-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mechanistic insight into AP-endonuclease 1 cleavage of abasic sites at stalled replication fork mimics. Nucleic Acids Res., 51, 2023
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7U53
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7U51
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![BU of 7u51 by Molmil](/molmil-images/mine/7u51) | |
7U52
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![BU of 7u52 by Molmil](/molmil-images/mine/7u52) | |
3L0X
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![BU of 3l0x by Molmil](/molmil-images/mine/3l0x) | |
7T19
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![BU of 7t19 by Molmil](/molmil-images/mine/7t19) | Rev1 Ternary Complex with dGTP and Ca2+ | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*TP*CP*GP*CP*TP*AP*CP*CP*AP*CP*AP*CP*CP*CP*C)-3'), ... | 著者 | Freudenthal, B.D, Weaver, T.M. | 登録日 | 2021-12-01 | 公開日 | 2022-05-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1. Nat Commun, 13, 2022
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7T1B
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![BU of 7t1b by Molmil](/molmil-images/mine/7t1b) | Rev1 Ternary Complex with rCTP and Ca2+ | 分子名称: | CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*CP*GP*CP*TP*AP*CP*CP*AP*CP*AP*CP*CP*CP*C)-3'), ... | 著者 | Freudenthal, B.D, Weaver, T.M. | 登録日 | 2021-12-01 | 公開日 | 2022-05-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1. Nat Commun, 13, 2022
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7T18
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![BU of 7t18 by Molmil](/molmil-images/mine/7t18) | Rev1 Ternary Complex with dTTP and Ca2+ | 分子名称: | CALCIUM ION, DNA (5'-D(*AP*TP*CP*GP*CP*TP*AP*CP*CP*AP*CP*AP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*GP*TP*GP*TP*GP*GP*TP*AP*G)-3'), ... | 著者 | Freudenthal, B.D, Weaver, T.M. | 登録日 | 2021-12-01 | 公開日 | 2022-05-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1. Nat Commun, 13, 2022
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7T1A
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![BU of 7t1a by Molmil](/molmil-images/mine/7t1a) | Rev1 Ternary Complex with dATP and Ca2+ | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*TP*CP*GP*CP*TP*AP*CP*CP*AP*CP*AP*CP*CP*CP*C)-3'), ... | 著者 | Freudenthal, B.D, Weaver, T.M. | 登録日 | 2021-12-01 | 公開日 | 2022-05-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1. Nat Commun, 13, 2022
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