4RLE
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![BU of 4rle by Molmil](/molmil-images/mine/4rle) | Crystal structure of the c-di-AMP binding PII-like protein DarA | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, NICKEL (II) ION, Uncharacterized protein YaaQ | Authors: | Dickmanns, A, Neumann, P, Ficner, R. | Deposit date: | 2014-10-16 | Release date: | 2014-12-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Identification, Characterization, and Structure Analysis of the Cyclic di-AMP-binding PII-like Signal Transduction Protein DarA. J.Biol.Chem., 290, 2015
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4TMW
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4TMT
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![BU of 4tmt by Molmil](/molmil-images/mine/4tmt) | Translation initiation factor eIF5B (517-858) mutant D533A from C. thermophilum, bound to GTPgammaS | Descriptor: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... | Authors: | Kuhle, B, Ficner, R. | Deposit date: | 2014-06-02 | Release date: | 2014-09-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | A monovalent cation acts as structural and catalytic cofactor in translational GTPases. Embo J., 33, 2014
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4TMZ
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4TMX
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![BU of 4tmx by Molmil](/molmil-images/mine/4tmx) | Translation initiation factor eIF5B (517-858) mutant D533N from C. thermophilum, bound to GTP and sodium | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Kuhle, B, Ficner, R. | Deposit date: | 2014-06-02 | Release date: | 2014-09-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A monovalent cation acts as structural and catalytic cofactor in translational GTPases. Embo J., 33, 2014
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4KR9
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4N6R
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![BU of 4n6r by Molmil](/molmil-images/mine/4n6r) | Crystal structure of VosA-VelB-complex | Descriptor: | SULFATE ION, VelB, VosA | Authors: | Ahmed, Y.L, Dickmanns, A, Neumann, P, Ficner, R. | Deposit date: | 2013-10-14 | Release date: | 2014-01-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Velvet Family of Fungal Regulators Contains a DNA-Binding Domain Structurally Similar to NF-kappa B. Plos Biol., 11, 2013
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3G38
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![BU of 3g38 by Molmil](/molmil-images/mine/3g38) | The catalytically inactive mutant Mth0212 (D151N) in complex with an 8 bp dsDNA | Descriptor: | 5'-D(*CP*CP*TP*GP*UP*GP*CP*GP*AP*T)-3', 5'-D(*CP*GP*CP*GP*CP*AP*GP*GP*C)-3', Exodeoxyribonuclease, ... | Authors: | Lakomek, K, Dickmanns, A, Ficner, R. | Deposit date: | 2009-02-02 | Release date: | 2010-03-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.04 Å) | Cite: | Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA J.Mol.Biol., 399, 2010
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4N3S
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4N3G
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4KR7
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![BU of 4kr7 by Molmil](/molmil-images/mine/4kr7) | Crystal structure of a 4-thiouridine synthetase - RNA complex with bound ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Probable tRNA sulfurtransferase, ... | Authors: | Neumann, P, Ficner, R, Lakomek, K. | Deposit date: | 2013-05-16 | Release date: | 2014-04-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.421 Å) | Cite: | Crystal structure of a 4-thiouridine synthetase-RNA complex reveals specificity of tRNA U8 modification. Nucleic Acids Res., 42, 2014
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4KR6
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4NCN
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4NCL
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4N3N
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4NWI
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![BU of 4nwi by Molmil](/molmil-images/mine/4nwi) | Crystal structure of cytosolic 5'-nucleotidase IIIB (cN-IIIB) bound to cytidine | Descriptor: | 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, 7-methylguanosine phosphate-specific 5'-nucleotidase, CHLORIDE ION, ... | Authors: | Monecke, T, Neumann, P, Ficner, R. | Deposit date: | 2013-12-06 | Release date: | 2014-03-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal Structures of the Novel Cytosolic 5'-Nucleotidase IIIB Explain Its Preference for m7GMP Plos One, 9, 2014
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4NCF
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4K51
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![BU of 4k51 by Molmil](/molmil-images/mine/4k51) | Crystal Structure of the PCI domain of eIF3a | Descriptor: | Eukaryotic translation initiation factor 3 subunit A | Authors: | Khoshnevis, S, Neumann, P, Ficner, R. | Deposit date: | 2013-04-12 | Release date: | 2014-01-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural integrity of the PCI domain of eIF3a/TIF32 is required for mRNA recruitment to the 43S pre-initiation complexes. Nucleic Acids Res., 42, 2014
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4NOX
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![BU of 4nox by Molmil](/molmil-images/mine/4nox) | Structure of the nine-bladed beta-propeller of eIF3b | Descriptor: | CHLORIDE ION, Eukaryotic translation initiation factor 3 subunit B | Authors: | Liu, Y, Neumann, P, Kuhle, B, Monecke, T, Ficner, R. | Deposit date: | 2013-11-20 | Release date: | 2014-09-17 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.722 Å) | Cite: | Translation initiation factor eIF3b contains a nine-bladed beta-propeller and interacts with the 40S ribosomal subunit Structure, 22, 2014
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4NV0
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![BU of 4nv0 by Molmil](/molmil-images/mine/4nv0) | Crystal structure of cytosolic 5'-nucleotidase IIIB (cN-IIIB) bound to 7-methylguanosine | Descriptor: | 7-METHYLGUANOSINE, 7-methylguanosine phosphate-specific 5'-nucleotidase, MAGNESIUM ION, ... | Authors: | Monecke, T, Neumann, P, Ficner, R. | Deposit date: | 2013-12-04 | Release date: | 2014-03-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal Structures of the Novel Cytosolic 5'-Nucleotidase IIIB Explain Its Preference for m7GMP Plos One, 9, 2014
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4N6Q
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![BU of 4n6q by Molmil](/molmil-images/mine/4n6q) | Crystal structure of VosA velvet domain | Descriptor: | IODIDE ION, NITRATE ION, VosA | Authors: | Ahmed, Y.L, Dickmanns, A, Neumann, P, Ficner, R. | Deposit date: | 2013-10-14 | Release date: | 2014-01-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | The Velvet Family of Fungal Regulators Contains a DNA-Binding Domain Structurally Similar to NF-kappa B. Plos Biol., 11, 2013
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3FBX
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![BU of 3fbx by Molmil](/molmil-images/mine/3fbx) | Crystal structure of the lysosomal 66.3 kDa protein from mouse solved by S-SAD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Lakomek, K, Dickmanns, A, Mueller, U, Ficner, R. | Deposit date: | 2008-11-20 | Release date: | 2009-03-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | De novo sulfur SAD phasing of the lysosomal 66.3 kDa protein from mouse Acta Crystallogr.,Sect.D, 65, 2009
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3CTR
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![BU of 3ctr by Molmil](/molmil-images/mine/3ctr) | Crystal structure of the RRM-domain of the poly(A)-specific ribonuclease PARN bound to m7GTP | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Poly(A)-specific ribonuclease PARN | Authors: | Monecke, T, Schell, S, Dickmanns, A, Ficner, R. | Deposit date: | 2008-04-14 | Release date: | 2008-07-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the RRM domain of poly(A)-specific ribonuclease reveals a novel m(7)G-cap-binding mode. J.Mol.Biol., 382, 2008
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3G2D
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![BU of 3g2d by Molmil](/molmil-images/mine/3g2d) | Complex of Mth0212 and a 4 bp dsDNA with 3'-overhang | Descriptor: | 5'-D(*CP*CP*TP*GP*UP*GP*CP*GP*AP*T)-3', 5'-D(*CP*GP*CP*G*CP*AP*GP*GP*C)-3', Exodeoxyribonuclease, ... | Authors: | Lakomek, K, Dickmanns, A, Ficner, R. | Deposit date: | 2009-01-31 | Release date: | 2010-03-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA J.Mol.Biol., 399, 2010
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3G00
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![BU of 3g00 by Molmil](/molmil-images/mine/3g00) | Mth0212 in complex with a 9bp blunt end dsDNA at 1.7 Angstrom | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-D(*CP*GP*TP*AP*TP*TP*AP*CP*G)-3', 5'-D(*CP*GP*TP*AP*UP*TP*AP*CP*G)-3', ... | Authors: | Lakomek, K, Dickmanns, A, Ficner, R. | Deposit date: | 2009-01-27 | Release date: | 2010-03-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA J.Mol.Biol., 399, 2010
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