4K51

Crystal Structure of the PCI domain of eIF3a

Summary for 4K51

Entry DOI	10.2210/pdb4k51/pdb
Descriptor	Eukaryotic translation initiation factor 3 subunit A (1 entity in total)
Functional Keywords	eif3, pci domain, translation initiation, biosynthetic protein
Biological source	Saccharomyces cerevisiae (Baker's yeast)
Cellular location	Cytoplasm (By similarity): P38249
Total number of polymer chains	2
Total formula weight	51228.23
Authors	Khoshnevis, S.,Neumann, P.,Ficner, R. (deposition date: 2013-04-12, release date: 2014-01-15, Last modification date: 2024-02-28)
Primary citation	Khoshnevis, S.,Gunisova, S.,Vlckova, V.,Kouba, T.,Neumann, P.,Beznoskova, P.,Ficner, R.,Valasek, L.S. Structural integrity of the PCI domain of eIF3a/TIF32 is required for mRNA recruitment to the 43S pre-initiation complexes. Nucleic Acids Res., 42:4123-4139, 2014 Cited by PubMed: 24423867 DOI: 10.1093/nar/gkt1369 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation