2ZIH
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![BU of 2zih by Molmil](/molmil-images/mine/2zih) | |
2ZII
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1YY9
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![BU of 1yy9 by Molmil](/molmil-images/mine/1yy9) | Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab Heavy chain, ... | Authors: | Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M. | Deposit date: | 2005-02-24 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.605 Å) | Cite: | Structural basis for inhibition of the epidermal growth factor receptor by cetuximab Cancer Cell, 7, 2005
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1YY8
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![BU of 1yy8 by Molmil](/molmil-images/mine/1yy8) | Crystal structure of the Fab fragment from the monoclonal antibody cetuximab/Erbitux/IMC-C225 | Descriptor: | Cetuximab Fab Heavy chain, Cetuximab Fab Light chain | Authors: | Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M. | Deposit date: | 2005-02-24 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for inhibition of the epidermal growth factor receptor by cetuximab Cancer Cell, 7, 2005
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2AHX
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![BU of 2ahx by Molmil](/molmil-images/mine/2ahx) | Crystal structure of ErbB4/HER4 extracellular domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-4, SULFATE ION, ... | Authors: | Bouyain, S, Longo, P.A, Li, S, Ferguson, K.M, Leahy, D.J. | Deposit date: | 2005-07-28 | Release date: | 2005-09-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.396 Å) | Cite: | The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand Proc.Natl.Acad.Sci.USA, 102, 2005
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7LEN
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![BU of 7len by Molmil](/molmil-images/mine/7len) | Crystal structure of the epidermal growth factor receptor extracellular region with R84K mutation in complex with epiregulin crystallized with trehalose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Hu, C, Leche II, C.A, Stayrook, S.E, Ferguson, K.M, Lemmon, M.A. | Deposit date: | 2021-01-14 | Release date: | 2021-11-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias. Nature, 602, 2022
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7LFR
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![BU of 7lfr by Molmil](/molmil-images/mine/7lfr) | Crystal structure of the epidermal growth factor receptor extracellular region with R84K mutation in complex with epiregulin crystallized with spermine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, Proepiregulin, ... | Authors: | Hu, C, Leche II, C.A, Stayrook, S.E, Ferguson, K.M, Lemmon, M.A. | Deposit date: | 2021-01-18 | Release date: | 2021-11-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias. Nature, 602, 2022
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7LFS
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![BU of 7lfs by Molmil](/molmil-images/mine/7lfs) | Crystal structure of the epidermal growth factor receptor extracellular region with A265V mutation in complex with epiregulin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 4 of Epidermal growth factor receptor, ... | Authors: | Hu, C, Leche II, C.A, Stayrook, S.E, Ferguson, K.M, Lemmon, M.A. | Deposit date: | 2021-01-18 | Release date: | 2021-11-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias. Nature, 602, 2022
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5UTK
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![BU of 5utk by Molmil](/molmil-images/mine/5utk) | |