4R5Y
 
 | | The complex structure of Braf V600E kinase domain with a novel Braf inhibitor | | 分子名称: | 5-({(1R,1aS,6bR)-1-[5-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one, Serine/threonine-protein kinase B-raf | | 著者 | Feng, Y, Peng, H, Zhang, Y, Liu, Y, Wei, M. | | 登録日 | 2014-08-22 | | 公開日 | 2016-02-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers.
Mol.Cancer Ther., 14, 2015
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5YIJ
 | | Structure of a Legionella effector with substrates | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, SdeA, Ubiquitin | | 著者 | Feng, Y, Mu, Y, Wang, H. | | 登録日 | 2017-10-05 | | 公開日 | 2018-05-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
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1JLI
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1Z7P
 | | Solution structure of reduced glutaredoxin C1 from Populus tremula x tremuloides | | 分子名称: | glutaredoxin | | 著者 | Feng, Y, Zhong, N, Rouhier, N, Jacquot, J.P, Xia, B. | | 登録日 | 2005-03-26 | | 公開日 | 2006-03-28 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Insight into Poplar Glutaredoxin C1 with a Bridging Iron-Sulfur Cluster at the Active Site
Biochemistry, 45, 2006
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6SXL
 | | Crystal structure of CrtE | | 分子名称: | Geranylgeranyl pyrophosphate synthase, PHOSPHATE ION | | 著者 | Feng, Y, Morgan, R.M.L, Nixon, P.J. | | 登録日 | 2019-09-26 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of Geranylgeranyl Pyrophosphate Synthase (CrtE) Involved in Cyanobacterial Terpenoid Biosynthesis.
Front Plant Sci, 11, 2020
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6SXN
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1HOV
 | | SOLUTION STRUCTURE OF A CATALYTIC DOMAIN OF MMP-2 COMPLEXED WITH SC-74020 | | 分子名称: | CALCIUM ION, MATRIX METALLOPROTEINASE-2, N-{4-[(1-HYDROXYCARBAMOYL-2-METHYL-PROPYL)-(2-MORPHOLIN-4-YL-ETHYL)-SULFAMOYL]-4-PENTYL-BENZAMIDE, ... | | 著者 | Feng, Y, Likos, J.J, Zhu, L, Woodward, H, Munie, G, McDonald, J.J, Stevens, A.M, Howard, C.P, De Crescenzo, G.A, Welsch, D, Shieh, H.-S, Stallings, W.C. | | 登録日 | 2000-12-11 | | 公開日 | 2001-12-12 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor
Biochim.Biophys.Acta, 1598, 2002
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2MK5
 | | Solution structure of a protein domain | | 分子名称: | Endolysin | | 著者 | Feng, Y, Gu, J. | | 登録日 | 2014-01-24 | | 公開日 | 2014-05-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and biochemical characterization reveals LysGH15 as an unprecedented "EF-hand-like" calcium-binding phage lysin.
Plos Pathog., 10, 2014
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2JTM
 | | Solution structure of Sso6901 from Sulfolobus solfataricus P2 | | 分子名称: | Putative uncharacterized protein | | 著者 | Feng, Y, Guo, L, Huang, L, Wang, J. | | 登録日 | 2007-08-03 | | 公開日 | 2008-04-29 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Biochemical and structural characterization of Cren7, a novel chromatin protein conserved among Crenarchaea
Nucleic Acids Res., 36, 2008
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4ZH3
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4ZH4
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4ZH2
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1Z7R
 | | Solution Structure of reduced glutaredoxin C1 from Populus tremula x tremuloides | | 分子名称: | glutaredoxin | | 著者 | Feng, Y, Zhong, N, Rouhier, N, Jacquot, J.P, Xia, B. | | 登録日 | 2005-03-26 | | 公開日 | 2006-03-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Insight into Poplar Glutaredoxin C1 with a Bridging Iron-Sulfur Cluster at the Active Site
Biochemistry, 45, 2006
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3CVA
 | | Human Bcl-xL containing a Trp to Ala mutation at position 137 | | 分子名称: | Apoptosis regulator Bcl-X | | 著者 | Feng, Y, Zhang, L, Hu, T, Shen, X, Chen, K, Jiang, H, Liu, D. | | 登録日 | 2008-04-18 | | 公開日 | 2009-03-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A conserved hydrophobic core at Bcl-x(L) mediates its structural stability and binding affinity with BH3-domain peptide of pro-apoptotic protein
Arch.Biochem.Biophys., 484, 2009
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4JND
 | | Structure of a C.elegans sex determining protein | | 分子名称: | Ca(2+)/calmodulin-dependent protein kinase phosphatase, MAGNESIUM ION | | 著者 | Feng, Y, Zhang, Y, Ge, J, Yang, M. | | 登録日 | 2013-03-15 | | 公開日 | 2013-06-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.652 Å) | | 主引用文献 | Structural insight into Caenorhabditis elegans sex-determining protein FEM-2.
J.Biol.Chem., 288, 2013
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6A9Y
 | | The crystal structure of Mu homology domain of SGIP1 | | 分子名称: | SH3-containing GRB2-like protein 3-interacting protein 1 | | 著者 | Feng, Y, Liu, X. | | 登録日 | 2018-07-16 | | 公開日 | 2018-09-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | SGIP1 dimerizes via intermolecular disulfide bond in mu HD domain during cellular endocytosis.
Biochem. Biophys. Res. Commun., 505, 2018
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2HR9
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6LW4
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6LP2
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4MEX
 | | Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. | | 登録日 | 2013-08-27 | | 公開日 | 2014-05-21 | | 最終更新日 | 2014-06-25 | | 実験手法 | X-RAY DIFFRACTION (3.902 Å) | | 主引用文献 | Transcription inhibition by the depsipeptide antibiotic salinamide A.
Elife, 3, 2014
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2JSN
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6KG9
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6KGF
 | | Crystal structure of CaDoc0917(R16D)-CaCohA2 complex at pH 8.2 | | 分子名称: | And cellulose-binding endoglucanase family 9 CelL ortholog dockerin domain, CALCIUM ION, Probably cellulosomal scaffolding protein, ... | | 著者 | Feng, Y, Yao, X. | | 登録日 | 2019-07-11 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules.
Sci Adv, 6, 2020
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6KGC
 | | Crystal structure of CaDoc0917(R49D)-CaCohA2 complex at pH 5.4 | | 分子名称: | And cellulose-binding endoglucanase family 9 CelL ortholog dockerin domain, CALCIUM ION, Probably cellulosomal scaffolding protein, ... | | 著者 | Feng, Y, Yao, X. | | 登録日 | 2019-07-11 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules.
Sci Adv, 6, 2020
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6KGD
 | | Crystal structure of CaDoc0917(R49D)-CaCohA2 complex at pH 8.0 | | 分子名称: | And cellulose-binding endoglucanase family 9 CelL ortholog dockerin domain, CALCIUM ION, Probably cellulosomal scaffolding protein, ... | | 著者 | Feng, Y, Yao, X. | | 登録日 | 2019-07-11 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules.
Sci Adv, 6, 2020
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