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PDB: 50 件

7MCA
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Structure of the S. cerevisiae origin recognition complex bound to the replication initiator Cdc6 and the ARS1 origin DNA.
分子名称: Cell division control protein 6, DNA (85-MER), MAGNESIUM ION, ...
著者Feng, X, Li, H.
登録日2021-04-01
公開日2021-06-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.
Nat Commun, 12, 2021
6SAF
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The Fk1 domain of FKBP51 in complex with (S)-(R)-3-(3,4-dimethoxyphenyl)-1-(3-(2-morpholinoethoxy)phenyl)propyl 1-((1R,4aR,8aR)-4-oxodecahydronaphthalene-1-carbonyl)piperidine-2-carboxylate
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, [(1~{R})-3-(3,4-dimethoxyphenyl)-1-[3-(2-morpholin-4-ylethoxy)phenyl]propyl] (2~{S})-1-[[(1~{R},4~{a}~{R},8~{a}~{R})-4-oxidanylidene-2,3,4~{a},5,6,7,8,8~{a}-octahydro-1~{H}-naphthalen-1-yl]carbonyl]piperidine-2-carboxylate
著者Feng, X, Sippel, C, Knaup, F, Bracher, A, Staibano, S, Romano, M.F, Hausch, F.
登録日2019-07-16
公開日2019-12-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A Novel Decalin-Based Bicyclic Scaffold for FKBP51-Selective Ligands.
J.Med.Chem., 63, 2020
7KOE
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Electron bifurcating flavoprotein Fix/EtfABCX
分子名称: Electron transfer flavoprotein, alpha subunit, beta subunit, ...
著者Feng, X, Li, H.
登録日2020-11-08
公開日2021-01-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Cryoelectron microscopy structure and mechanism of the membrane-associated electron-bifurcating flavoprotein Fix/EtfABCX.
Proc.Natl.Acad.Sci.USA, 118, 2021
8DVI
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T4 bacteriophage primosome with single strand DNA, State 2
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA (70-MER), DNA primase, ...
著者Feng, X, Li, H.
登録日2022-07-29
公開日2023-06-14
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
8DVF
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T4 Bacteriophage primosome with single strand DNA, state 1
分子名称: DNA (5'-D(P*GP*GP*CP*TP*G)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase, ...
著者Feng, X, Li, H.
登録日2022-07-28
公開日2023-06-14
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
8DTP
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BU of 8dtp by Molmil
Close state of T4 bacteriophage gp41 hexamer bound with single strand DNA
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DnaB-like replicative helicase, MAGNESIUM ION, ...
著者Feng, X, Li, H.
登録日2022-07-26
公開日2023-06-14
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
8DW6
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T4 bacteriophage primosome with single-strand DNA, State 3
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA (70-MER), DNA primase, ...
著者Feng, X, Li, H.
登録日2022-07-31
公開日2023-06-14
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
8DUO
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BU of 8duo by Molmil
DNA-free T4 Bacteriophage gp41 hexamer
分子名称: DnaB-like replicative helicase, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Feng, X, Li, H.
登録日2022-07-27
公開日2023-06-14
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
8DUE
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BU of 8due by Molmil
Open state of T4 bacteriophage gp41 hexamer bound with single strand DNA
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DnaB-like replicative helicase, MAGNESIUM ION, ...
著者Feng, X, Li, H.
登録日2022-07-27
公開日2023-06-14
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
8DWJ
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Primase of mutant bacteriophage T4 primosome with single strand DNA/RNA primer hybrid in primer exiting state
分子名称: DNA (70-MER), DNA primase, RNA(5'-ppp-GCCGA-3'), ...
著者Feng, X, Li, H.
登録日2022-08-01
公開日2023-06-14
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
7T30
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BU of 7t30 by Molmil
Structure of electron bifurcating Ni-Fe hydrogenase complex HydABCSL in FMN/NAD(H) bound state
分子名称: CARBONMONOXIDE-(DICYANO) IRON, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
著者Feng, X, Li, H.
登録日2021-12-06
公開日2022-03-16
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure and electron transfer pathways of an electron-bifurcating NiFe-hydrogenase.
Sci Adv, 8, 2022
7T2R
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BU of 7t2r by Molmil
Structure of electron bifurcating Ni-Fe hydrogenase complex HydABCSL in FMN-free apo state
分子名称: CARBONMONOXIDE-(DICYANO) IRON, FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, ...
著者Feng, X, Li, H.
登録日2021-12-06
公開日2022-03-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure and electron transfer pathways of an electron-bifurcating NiFe-hydrogenase.
Sci Adv, 8, 2022
8GAO
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BU of 8gao by Molmil
bacteriophage T4 stalled primosome with mutant gp41-E227Q
分子名称: DNA (70-mer), DNA primase, DnaB-like replicative helicase, ...
著者Feng, X, Li, H.
登録日2023-02-23
公開日2023-06-07
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
8G0Z
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BU of 8g0z by Molmil
Mutant bacteriophage T4 gp41 helicase hexamer bound with single strand DNA and ATPgammaS in the stalled primosome
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DnaB-like replicative helicase, MAGNESIUM ION, ...
著者Feng, X, Li, H.
登録日2023-02-01
公開日2023-06-14
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
5DIT
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BU of 5dit by Molmil
The Fk1 domain of FKBP51 in complex with the new synthetic ligand (1R)-3-(3,4-dimethoxyphenyl)-1-f3-[2-(morpholin-4-yl)ethoxy]phenylgpropyl(2S)-1-[(2S,3R)-2-cyclohexyl-3-hydroxybutanoyl]piperidine-2-carboxylate
分子名称: (1R)-3-(3,4-dimethoxyphenyl)-1-{3-[2-(morpholin-4-yl)ethoxy]phenyl}propyl (2S)-1-[(2S,3R)-2-cyclohexyl-3-hydroxybutanoyl]piperidine-2-carboxylate, Peptidyl-prolyl cis-trans isomerase FKBP5
著者Feng, X, Sippel, C, Bracher, A, Hausch, F.
登録日2015-09-01
公開日2015-10-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure-Affinity Relationship Analysis of Selective FKBP51 Ligands.
J.Med.Chem., 58, 2015
6LJH
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BU of 6ljh by Molmil
Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua in complex with NAD+
分子名称: Alcohol dehydrogenase 1, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Feng, X, Fan, S, Li, M, Zou, S, Lv, G, Wu, G, Jin, Y, Yang, Z.
登録日2019-12-16
公開日2020-12-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua in complex with NAD+
To Be Published
4ONC
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BU of 4onc by Molmil
Crystal Structure of Mycobacterium Tuberculosis Decaprenyl Diphosphate Synthase in Complex with BPH-640
分子名称: Decaprenyl diphosphate synthase, [hydroxy(1,1':3',1''-terphenyl-3-yl)methanediyl]bis(phosphonic acid)
著者Feng, X, Chan, H.C, Ko, T.P.
登録日2014-01-28
公開日2014-04-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis
J.Am.Chem.Soc., 136, 2014
7CYI
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BU of 7cyi by Molmil
Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua
分子名称: Alcohol dehydrogenase 1, ZINC ION
著者Feng, X, Fan, S, Lv, G, Li, M, Wu, G, Jin, Y, Yang, Z.
登録日2020-09-03
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structure of Alcohol dehydrogenase 1 from Artemisia annua
To Be Published
4MY5
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BU of 4my5 by Molmil
Crystal structure of the aromatic amino acid aminotransferase from Streptococcus mutants
分子名称: Putative amino acid aminotransferase
著者Cong, X, Li, X, Ge, J, Feng, Y, Feng, X, Li, S.
登録日2013-09-27
公開日2014-10-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.194 Å)
主引用文献Crystal structure of the aromatic-amino-acid aminotransferase from Streptococcus mutans.
Acta Crystallogr.,Sect.F, 75, 2019
7X9P
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BU of 7x9p by Molmil
Crystal structure of human STING complexed with compound BSP17
分子名称: 4-[6-methoxy-5-[3-[[6-methoxy-2-(4-oxidanyl-4-oxidanylidene-butanoyl)-1-benzoselenophen-5-yl]oxy]propoxy]-1-benzoselenophen-2-yl]-4-oxidanylidene-butanoic acid, Stimulator of interferon genes protein
著者Pan, L, Guan, X, Feng, X, Li, Z, Bian, J.
登録日2022-03-15
公開日2023-03-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery of Selenium-containing STING agonists as orally available anti tumor agents
To be published
8JKS
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BU of 8jks by Molmil
T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAGA motif
分子名称: GAGA-Forward, GAGA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
8JKN
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BU of 8jkn by Molmil
T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAAA motif
分子名称: GAAA-Forward, GAAA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
8JKO
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BU of 8jko by Molmil
T95R mutant IRF4 DNA-binding domain bound to an DNA containing GATA motif
分子名称: GATA-Forward, GATA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
8JKQ
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BU of 8jkq by Molmil
T95R mutant IRF4 DNA-binding domain bound to an DNA containing GACA motif
分子名称: GACA-Forward, GACA-Reverse, Interferon regulatory factor 4
著者Wang, G, Feng, X, Ding, J.
登録日2023-06-01
公開日2023-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Structure, 31, 2023
7L6N
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BU of 7l6n by Molmil
The Mycobacterium tuberculosis ClpB disaggregase hexamer structure with three locally refined ClpB middle domains and three DnaK nucleotide binding domains
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, Chaperone protein DnaK, ...
著者Yin, Y.Y, Feng, X, Li, H.
登録日2020-12-23
公開日2021-05-26
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
Cell Rep, 35, 2021

 

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