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PDB: 100 件

3ORG
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Crystal Structure of a eukaryotic CLC transporter
分子名称: CHLORIDE ION, CmCLC
著者Feng, L, MacKinnon, R.
登録日2010-09-07
公開日2010-10-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of a eukaryotic CLC transporter defines an intermediate state in the transport cycle.
Science, 330, 2010
4O5B
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HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid
分子名称: (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid, Integrase, SULFATE ION
著者Feng, L, Kvaratskhelia, M.
登録日2013-12-19
公開日2014-07-02
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase.
Plos Pathog., 10, 2014
4O55
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HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid
分子名称: (2S)-tert-butoxy[6-(5-chloro-1H-benzimidazol-2-yl)-2,5-dimethyl-4-phenylpyridin-3-yl]ethanoic acid, Integrase, SULFATE ION
著者Feng, L, Kvaratskhelia, M.
登録日2013-12-19
公開日2014-07-02
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase.
Plos Pathog., 10, 2014
4LQ1
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Crystal Structure of E.Coli Branching Enzyme in complex with maltohexaose
分子名称: 1,4-alpha-glucan branching enzyme GlgB, GLYCEROL, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
著者Feng, L, Geiger, J.H.
登録日2013-07-17
公開日2015-04-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal Structures of Escherichia coli Branching Enzyme in Complex with Linear Oligosaccharides.
Biochemistry, 54, 2015
4GVM
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HIV-1 Integrase Catalytic Core Domain A128T Mutant Complexed with Allosteric Inhibitor
分子名称: (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](tert-butoxy)ethanoic acid, ARSENIC, Gag-Pol polyprotein
著者Feng, L, Kvaratskhelia, M.
登録日2012-08-30
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors.
J.Biol.Chem., 288, 2013
4JLH
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HIV-1 Integrase Catalytic Core Domain A128T Mutant Complexed with Allosteric Inhibitor
分子名称: (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](methoxy)ethanoic acid, HIV-1 Integrase catalytic core domain, SULFATE ION
著者Feng, L, Kvaratskhelia, M.
登録日2013-03-12
公開日2013-05-01
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors.
J.Biol.Chem., 288, 2013
4ID1
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HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor
分子名称: (2S)-tert-butoxy[4-(3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid, Gag-Pol polyprotein, SULFATE ION
著者Feng, L, Kvaratskhelia, M.
登録日2012-12-11
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation.
Proc.Natl.Acad.Sci.USA, 110, 2013
5E70
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Crystal structure of Ecoli Branching Enzyme with gamma cyclodextrin
分子名称: 1,4-alpha-glucan branching enzyme GlgB, Cyclooctakis-(1-4)-(alpha-D-glucopyranose), GLYCEROL
著者Feng, L, Nosrati, M, Geiger, J.H.
登録日2015-10-11
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal structures of Escherichia coli branching enzyme in complex with cyclodextrins.
Acta Crystallogr D Struct Biol, 72, 2016
5E6Z
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Crystal structure of Ecoli Branching Enzyme with beta cyclodextrin
分子名称: 1,4-alpha-glucan branching enzyme GlgB, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), GLYCEROL
著者Feng, L, Nosrati, M, Geiger, J.H.
登録日2015-10-11
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.878 Å)
主引用文献Crystal structures of Escherichia coli branching enzyme in complex with cyclodextrins.
Acta Crystallogr D Struct Biol, 72, 2016
5E6Y
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Crystal structure of E.Coli branching enzyme in complex with alpha cyclodextrin
分子名称: 1,4-alpha-glucan branching enzyme GlgB, Cyclohexakis-(1-4)-(alpha-D-glucopyranose), GLYCEROL
著者Feng, L, Nosrati, M, Geiger, J.H.
登録日2015-10-11
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of Escherichia coli branching enzyme in complex with cyclodextrins.
Acta Crystallogr D Struct Biol, 72, 2016
6ZT5
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Complex between a homodimer of Mycobacterium smegmatis MfpA and a single copy of the N-terminal 47 kDa fragment of the Mycobacterium smegmatis DNA Gyrase B subunit
分子名称: DNA gyrase subunit B, Pentapeptide repeat protein MfpA, SULFATE ION
著者Feng, L, Mundy, J.E.A, Stevenson, C.E.M, Mitchenall, L.A, Lawson, D.M, Mi, K, Maxwell, A.
登録日2020-07-17
公開日2021-03-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic.
Proc.Natl.Acad.Sci.USA, 118, 2021
6ZT3
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N-terminal 47 kDa fragment of the Mycobacterium smegmatis DNA Gyrase B subunit complexed with ADPNP
分子名称: 1,2-ETHANEDIOL, DNA gyrase subunit B, MAGNESIUM ION, ...
著者Feng, L, Mundy, J.E.A, Stevenson, C.E.M, Mitchenall, L.A, Lawson, D.M, Mi, K, Maxwell, A.
登録日2020-07-17
公開日2021-03-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic.
Proc.Natl.Acad.Sci.USA, 118, 2021
6ZT4
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Pentapeptide repeat protein MfpA from Mycobacterium smegmatis
分子名称: 1,2-ETHANEDIOL, Pentapeptide repeat protein MfpA
著者Feng, L, Mundy, J.E.A, Stevenson, C.E.M, Mitchenall, L.A, Lawson, D.M, Mi, K, Maxwell, A.
登録日2020-07-17
公開日2021-03-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic.
Proc.Natl.Acad.Sci.USA, 118, 2021
8GQW
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BU of 8gqw by Molmil
The Crystal Structures of a Swine SLA-2*HB01 Molecules Complexed with a CTL epitope from Asia1 serotype of Foot-and-mouth disease virus
分子名称: Hu64, MHC class I antigen, beta 2 microglobulin
著者Feng, L, Gao, Y.Y, Sun, M.W, Li, Z.B, Zhang, Q, Yang, J, Qiao, C, Jin, H, Feng, H.S, Xian, Y.H, Qi, J.X, Gao, G.F, Liu, W.J, Gao, F.S.
登録日2022-08-31
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献The Parallel Presentation of Two Functional CTL Epitopes Derived from the O and Asia 1 Serotypes of Foot-and-Mouth Disease Virus and Swine SLA-2*HB01: Implications for Universal Vaccine Development.
Cells, 11, 2022
8GQV
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The Crystal Structures of a Swine SLA-2*HB01 Molecules Complexed with a CTL epitope from Asia1 serotype of Foot-and-mouth disease virus
分子名称: As64, MHC class I antigen, beta 2 microglobulin
著者Feng, L, Gao, Y.Y, Sun, M.W, Li, Z.B, Zhang, Q, Yang, J, Qiao, C, Jin, H, Feng, H.S, Xian, Y.H, Qi, J.X, Gao, G.F, Liu, W.J, Gao, F.S.
登録日2022-08-31
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Parallel Presentation of Two Functional CTL Epitopes Derived from the O and Asia 1 Serotypes of Foot-and-Mouth Disease Virus and Swine SLA-2*HB01: Implications for Universal Vaccine Development.
Cells, 11, 2022
5JL4
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BU of 5jl4 by Molmil
Inhibitor resistant mutant catalytic core domain of HIV-1 Integrase
分子名称: Integrase, SULFATE ION
著者Feng, L, Kobe, M, Kvaratskhelia, M.
登録日2016-04-26
公開日2017-10-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.758 Å)
主引用文献Resistance to pyridine-based inhibitor KF116 reveals an unexpected role of integrase in HIV-1 Gag-Pol polyprotein proteolytic processing.
J. Biol. Chem., 292, 2017
8INJ
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Crystal structure of UGT74AN3-UDP-DIG
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIGITOXIGENIN, Glycosyltransferase, ...
著者Feng, L, Wei, H.
登録日2023-03-10
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Crystal structure of UGT74AN3-UDP-DIG
To Be Published
8JJQ
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Structure of SenB in complex with UDP-GalNAc at 1.64 Angstroms resolution
分子名称: TIGR04348 family glycosyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE
著者Feng, L, Wei, H.
登録日2023-05-31
公開日2024-02-07
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structure of SenB in complex with UDP-GalNAc at 1.64 Angstroms resolution
To Be Published
8IN7
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BU of 8in7 by Molmil
Crystal structure of UGT74AN3-UDP
分子名称: Glycosyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE
著者Feng, L, Wei, H.
登録日2023-03-08
公開日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of UGT74AN3-UDP
To Be Published
4RZE
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BU of 4rze by Molmil
Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant
分子名称: GLYCEROL, Nuclear receptor subfamily 4 group A member 1
著者Fengwei, L, Xuyang, T, Anzhong, L, Li, L, Yuan, L, Hangzi, C, Qiao, W, Tianwei, L.
登録日2014-12-21
公開日2015-03-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
7N98
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Cryo-EM structure of MFSD2A
分子名称: Sodium-dependent lysophosphatidylcholine symporter 1
著者Zhang, J, Feng, L.
登録日2021-06-17
公開日2021-08-04
最終更新日2021-09-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure and mechanism of blood-brain-barrier lipid transporter MFSD2A.
Nature, 596, 2021
6R48
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Crystal structure of LPOR (Synechocystis) complexed with NADPH at 1.87A resolution.
分子名称: CHLORIDE ION, Light-dependent protochlorophyllide reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhou, A, Feng, L.
登録日2019-03-22
公開日2019-10-30
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis.
Nature, 574, 2019
6R46
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Crystal structure of LPOR (Thermosynechococcus elongatus) complexed with NADP+ at 2.5A resolution
分子名称: CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-protochlorophyllide oxidoreductase, ...
著者Zhou, A, Feng, L.
登録日2019-03-22
公開日2019-10-30
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis.
Nature, 574, 2019
7SL9
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CryoEM structure of SMCT1
分子名称: Sodium-coupled monocarboxylate transporter 1, butanoic acid, nanobody Nb2
著者Qu, Q, Han, L, Panova, O, Feng, L, Skiniotis, G.
登録日2021-10-23
公開日2021-12-15
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure and mechanism of the SGLT family of glucose transporters.
Nature, 601, 2022
7SLA
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CryoEM structure of SGLT1 at 3.15 Angstrom resolution
分子名称: CHOLESTEROL HEMISUCCINATE, Sodium/glucose cotransporter 1, nanobody Nb1
著者Qu, Q, Han, L, Panova, O, Feng, L, Skiniotis, G.
登録日2021-10-23
公開日2021-12-15
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Structure and mechanism of the SGLT family of glucose transporters.
Nature, 601, 2022

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