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PDB: 72 件
4TW5
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Structure Of the First Two Thioredoxin Domains of Saccharomyces cerevisiae Eps1p
分子名称: Eps1p
著者Fass, D, Biran, S.
登録日2014-06-30
公開日2014-12-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献The eps1p protein disulfide isomerase conserves classic thioredoxin superfamily amino Acid motifs but not their functional geometries.
Plos One, 9, 2014
4IJ3
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Oxidoreductase Fragment of Human QSOX1 in Complex with a FAB Fragment from an Anti- Human QSOX1 Antibody
分子名称: Heavy chain of FAB fragment, Light chain of FAB fragment, PHOSPHATE ION, ...
著者Fass, D, Grossman, I.
登録日2012-12-21
公開日2013-11-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An Inhibitory Antibody Blocks the First Step in the Dithiol/Disulfide Relay Mechanism of the Enzyme QSOX1.
J.Mol.Biol., 425, 2013
5D96
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Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from an Antibody Targeting Mouse and Human QSOX1
分子名称: Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1, Light chain of Fab fragment from an antibody targeting mouse and human QSOX1, Sulfhydryl oxidase 1
著者Fass, D, Grossman, I.
登録日2015-08-18
公開日2016-02-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
3Q6O
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Oxidoreductase Fragment of Human QSOX1
分子名称: SULFATE ION, Sulfhydryl oxidase 1
著者Fass, D, Alon, A.
登録日2011-01-03
公開日2012-05-30
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The dynamic disulphide relay of quiescin sulphydryl oxidase.
Nature, 488, 2012
2I1A
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BU of 2i1a by Molmil
A Retroviral Protease-Like Domain in the Eukaryotic Protein Ddi1
分子名称: DNA damage-inducible protein DDI1
著者Fass, D, Sirkis, R.
登録日2006-08-14
公開日2006-10-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ddi1, a eukaryotic protein with the retroviral protease fold.
J.Mol.Biol., 364, 2006
3T59
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C76A/C455S mutant of mouse QSOX1 containing an interdomain disulfide
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Sulfhydryl oxidase 1
著者Fass, D, Alon, A, Gat, Y.
登録日2011-07-27
公開日2012-05-30
最終更新日2012-08-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The dynamic disulphide relay of quiescin sulphydryl oxidase.
Nature, 488, 2012
3T58
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C76A/C455S mutant of mouse QSOX1 containing an interdomain disulfide
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Sulfhydryl oxidase 1
著者Fass, D, Alon, A, Gat, Y.
登録日2011-07-27
公開日2012-05-30
最終更新日2012-08-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The dynamic disulphide relay of quiescin sulphydryl oxidase.
Nature, 488, 2012
1MOF
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BU of 1mof by Molmil
COAT PROTEIN
分子名称: CHLORIDE ION, MOLONEY MURINE LEUKEMIA VIRUS P15
著者Fass, D, Harrison, S.C, Kim, P.S.
登録日1996-04-02
公開日1996-10-14
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Retrovirus envelope domain at 1.7 angstrom resolution.
Nat.Struct.Biol., 3, 1996
3NVJ
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Crystal structure of the C143A/C166A mutant of Ero1p
分子名称: 1-ETHYL-PYRROLIDINE-2,5-DIONE, CADMIUM ION, Endoplasmic oxidoreductin-1, ...
著者Fass, D, Vonshak, O.
登録日2010-07-08
公開日2010-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Steps in reductive activation of the disulfide-generating enzyme Ero1p
Protein Sci., 19, 2010
1AJJ
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BU of 1ajj by Molmil
LDL RECEPTOR LIGAND-BINDING MODULE 5, CALCIUM-COORDINATING
分子名称: CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR, SULFATE ION
著者Fass, D, Blacklow, S.C, Kim, P.S, Berger, J.M.
登録日1997-05-04
公開日1997-07-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module.
Nature, 388, 1997
1BJT
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BU of 1bjt by Molmil
TOPOISOMERASE II RESIDUES 409-1201
分子名称: TOPOISOMERASE II
著者Fass, D, Bogden, C.E, Berger, J.M.
登録日1998-06-29
公開日1999-05-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Quaternary changes in topoisomerase II may direct orthogonal movement of two DNA strands.
Nat.Struct.Biol., 6, 1999
1B79
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N-TERMINAL DOMAIN OF DNA REPLICATION PROTEIN DNAB
分子名称: DnaB Helicase
著者Fass, D, Bogden, C.E, Berger, J.M.
登録日1999-01-28
公開日1999-06-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the N-terminal domain of the DnaB hexameric helicase.
Structure Fold.Des., 7, 1999
1AOL
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BU of 1aol by Molmil
FRIEND MURINE LEUKEMIA VIRUS RECEPTOR-BINDING DOMAIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GP70, ZINC ION
著者Fass, D, Davey, R.A, Hamson, C.A, Kim, P.S, Cunningham, J.M, Berger, J.M.
登録日1997-07-08
公開日1997-10-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolution.
Science, 277, 1997
1A8V
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BU of 1a8v by Molmil
STRUCTURE OF THE RNA-BINDING DOMAIN OF THE RHO TRANSCRIPTION TERMINATOR
分子名称: COPPER (II) ION, TRANSCRIPTION TERMINATION FACTOR RHO
著者Fass, D, Bogden, C, Berger, J.M.
登録日1998-03-28
公開日1999-05-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structural basis for terminator recognition by the Rho transcription termination factor.
Mol.Cell, 3, 1999
1EO6
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BU of 1eo6 by Molmil
CRYSTAL STRUCTURE OF GATE-16
分子名称: GOLGI-ASSOCIATED ATPASE ENHANCER OF 16 KD
著者Paz, Y, Elazar, Z, Fass, D.
登録日2000-03-22
公開日2000-09-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of GATE-16, membrane transport modulator and mammalian ortholog of autophagocytosis factor Aut7p.
J.Biol.Chem., 275, 2000
7ZWH
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BU of 7zwh by Molmil
VWF Tubules of D1D2 and D'D3A1 domains
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Javitt, G, Fass, D.
登録日2022-05-19
公開日2022-07-13
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Assembly of von Willebrand factor tubules with in vivo helical parameters requires A1 domain insertion.
Blood, 140, 2022
3M31
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BU of 3m31 by Molmil
Structure of the C150A/C295A mutant of S. cerevisiae Ero1p
分子名称: 1-ETHYL-PYRROLIDINE-2,5-DIONE, CADMIUM ION, Endoplasmic oxidoreductin-1, ...
著者Heldman, N, Fass, D.
登録日2010-03-08
公開日2010-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Steps in reductive activation of the disulfide-generating enzyme Ero1p
Protein Sci., 19, 2010
8QCI
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BU of 8qci by Molmil
FCGBP D10 Assembly Segment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
著者Yeshaya, N, Fass, D.
登録日2023-08-27
公開日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献VWD domain stabilization by autocatalytic Asp-Pro cleavage.
Protein Sci., 33, 2024
6RBF
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BU of 6rbf by Molmil
Mucin 2 D3 domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
著者Javitt, G, Fass, D.
登録日2019-04-10
公開日2019-08-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献Intestinal Gel-Forming Mucins Polymerize by Disulfide-Mediated Dimerization of D3 Domains.
J.Mol.Biol., 431, 2019
8AON
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BU of 8aon by Molmil
Oxidoreductase fragment of human QSOX1 in complex with a Fab fragment of a humanized anti-QSOX1 antibody
分子名称: GLYCEROL, Heavy chain, Light chain, ...
著者Khmelnitsky, L, Fass, D.
登録日2022-08-08
公開日2023-08-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Reliable energy-based antibody humanization and stabilization
To Be Published
7A5O
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Human MUC2 AAs 21-1397
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Javitt, G, Khmelnitsky, L, Albert, L, Elad, N, Ilani, T, Diskin, R, Fass, D.
登録日2020-08-21
公開日2020-10-21
最終更新日2020-11-11
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Assembly Mechanism of Mucin and von Willebrand Factor Polymers.
Cell, 183, 2020
8CK2
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MUC2 CysD1 G1352S
分子名称: ACETATE ION, CALCIUM ION, Mucin-2, ...
著者Khmelnitsky, L, Fass, D.
登録日2023-02-14
公開日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Pulmonary Fibrosis Mutation Undermines Mucin 5B Supramolecular Assembly
To Be Published
6HF1
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Mutant oxidoreductase fragment of mouse QSOX1 in complex with an antibody Fab
分子名称: Fab 316 heavy chain, Fab 316 light chain, Sulfhydryl oxidase 1
著者Grossman-Haham, I, Fass, D.
登録日2018-08-21
公開日2019-04-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献cis-Proline mutants of quiescin sulfhydryl oxidase 1 with altered redox properties undermine extracellular matrix integrity and cell adhesion in fibroblast cultures.
Protein Sci., 28, 2019
6GC2
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AbLIFT: Antibody stability and affinity optimization by computational design of the variable light-heavy chain interface
分子名称: Heavy chain, Light Chain
著者Warszawski, S, Katz, A, Khmelnitsky, L, Ben Nissan, G, Javitt, G, Dym, O, Unger, T, Knop, O, Diskin, R, Albeck, S, Fass, D, Sharon, M, Fleishman, S.J.
登録日2018-04-17
公開日2019-05-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces.
Plos Comput.Biol., 15, 2019
2A8V
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RHO TRANSCRIPTION TERMINATION FACTOR/RNA COMPLEX
分子名称: 5'-R(P*CP*CP*C)-3', 5'-R(P*CP*CP*CP*CP*CP*C)-3', RNA BINDING DOMAIN OF RHO TRANSCRIPTION TERMINATION FACTOR
著者Bogden, C.E, Fass, D, Bergman, N, Nichols, M.D, Berger, J.M.
登録日1998-11-08
公開日1999-04-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structural basis for terminator recognition by the Rho transcription termination factor.
Mol.Cell, 3, 1999

 

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