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PDB: 3 件

8ETM
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BU of 8etm by Molmil
Human triacylglycerol synthesizing enzyme DGAT1 in complex with DGAT1IN1 inhibitor
分子名称: Diacylglycerol O-acyltransferase 1, [(1S,4r)-4-{4-[(4S)-2-({[4-(trifluoromethoxy)phenyl]methyl}carbamoyl)imidazo[1,2-a]pyridin-6-yl]phenyl}cyclohexyl]acetic acid
著者Sui, X, Kun, W, Walther, T, Farese, R, Liao, M.
登録日2022-10-17
公開日2023-06-07
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.
Nat Commun, 14, 2023
8ERC
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BU of 8erc by Molmil
Human Membrane-bound O-acyltransferase 7
分子名称: Lysophospholipid acyltransferase 7
著者Wang, K, Liao, M, Farese, R.V, Walther, T.C.
登録日2022-10-11
公開日2023-09-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification.
Nat Commun, 14, 2023
8ESM
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BU of 8esm by Molmil
Human triacylglycerol synthesizing enzyme DGAT1 in complex with T863 inhibitor
分子名称: Diacylglycerol O-acyltransferase 1, {(1r,4r)-4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexyl}acetic acid
著者Sui, X, Kun, W, Walther, T, Farese, R, Liao, M.
登録日2022-10-14
公開日2023-06-07
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.
Nat Commun, 14, 2023

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件を2024-07-24に公開中

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