5MX6
 
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9F17
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8SCP
 | | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 1h | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | 著者 | Fang, Z, Lelyveld, V.S, Szostak, J.W. | | 登録日 | 2023-04-05 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
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8SCR
 | | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 4h | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | 著者 | Fang, Z, Lelyveld, V.S, Szostak, J.W. | | 登録日 | 2023-04-05 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
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8SCQ
 | | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 2h | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | 著者 | Fang, Z, Lelyveld, V.S, Szostak, J.W. | | 登録日 | 2023-04-05 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
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8SCS
 | | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 8h | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | 著者 | Fang, Z, Lelyveld, V.S, Szostak, J.W. | | 登録日 | 2023-04-05 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
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6CC9
 | | NMR data-driven model of GTPase KRas-GMPPNP:Cmpd2 complex tethered to a nanodisc | | 分子名称: | (2R,4S)-4-[(5-bromo-1H-indole-3-carbonyl)amino]-2-[(4-chlorophenyl)methyl]piperidin-1-ium, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, ... | | 著者 | Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M. | | 登録日 | 2018-02-06 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site.
Cell Chem Biol, 25, 2018
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6PTS
 | | NMR data-driven model of KRas-GMPPNP:RBD-CRD complex tethered to a nanodisc (state A) | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... | | 著者 | Fang, Z, Lee, K, Gasmi-Seabrook, G, Ikura, M, Marshall, C.B. | | 登録日 | 2019-07-16 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6PTW
 | | NMR data-driven model of KRas-GMPPNP:RBD-CRD complex tethered to a nanodisc (state B) | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... | | 著者 | Fang, Z, Lee, K, Gasmi-Seabrook, G, Ikura, M, Marshall, C.B. | | 登録日 | 2019-07-16 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6CCX
 | | NMR data-driven model of GTPase KRas-GMPPNP:Cmpd2 complex tethered to a nanodisc | | 分子名称: | (2R,4S)-4-[(5-bromo-1H-indole-3-carbonyl)amino]-2-[(4-chlorophenyl)methyl]piperidin-1-ium, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, ... | | 著者 | Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M. | | 登録日 | 2018-02-07 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site.
Cell Chem Biol, 25, 2018
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6CCH
 | | NMR data-driven model of GTPase KRas-GMPPNP tethered to a nanodisc (E3 state) | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... | | 著者 | Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M. | | 登録日 | 2018-02-07 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site.
Cell Chem Biol, 25, 2018
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8SCT
 | | Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 24h | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... | | 著者 | Fang, Z, Lelyveld, V.S, Szostak, J.W. | | 登録日 | 2023-04-05 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
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3UT6
 | | Crystal structure of E. Coli PNP complexed with PO4 and formycin A | | 分子名称: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type | | 著者 | Stefanic, Z. | | 登録日 | 2011-11-25 | | 公開日 | 2012-05-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | | 主引用文献 | New phosphate binding sites in the crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with phosphate and formycin A.
Febs Lett., 586, 2012
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5USE
 | | 5-Se-T4-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant | | 分子名称: | DNA (5'-D(*AP*TP*GP*(T5S)P*CP*G)-3'), MAGNESIUM ION, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), ... | | 著者 | Fang, Z, Qin, L, Huang, Z. | | 登録日 | 2017-02-13 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate
Chemistryselect, 8, 2023
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5USG
 | | 5-Se-T2/4-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant | | 分子名称: | DNA (5'-D(*AP*(T5S)P*GP*(T5S)P*CP*G)-3'), MAGNESIUM ION, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), ... | | 著者 | Fang, Z, Qin, L, Huang, Z. | | 登録日 | 2017-02-13 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate
Chemistryselect, 8, 2023
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5US2
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5USA
 | | 5-Se-T2-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant | | 分子名称: | DNA (5'-D(*AP*(T5S)P*GP*TP*CP*G)-3'), MAGNESIUM ION, RNA (5'-R(*UP*CP*GP*AP*CP*A)-3'), ... | | 著者 | Fang, Z, Qin, L, Huang, Z. | | 登録日 | 2017-02-13 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Synthesis of Pyrimidine Modified Seleno-DNA as a Novel Approach to Antisense Candidate
Chemistryselect, 8, 2023
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5W7N
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5MX8
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8TDY
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8TE2
 | |
9JJI
 | | Local refinement of RHDV GI.2 T=1 VLP | | 分子名称: | Capsid protein | | 著者 | Ruan, Z, Shao, Q, Song, Y, Hu, B, Fan, Z, Wei, H, Liu, Y, Wang, F, Fang, Q. | | 登録日 | 2024-09-13 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Near-atomic structures of RHDV reveal insights into capsid assembly and different conformations between mature virion and VLP
J.Virol.
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9JJH
 | | Cryo-EM structure of a T=1 VLP of RHDV GI.2 with N-terminal 1-37 residues truncated | | 分子名称: | Capsid protein | | 著者 | Ruan, Z, Shao, Q, Song, Y, Hu, B, Fan, Z, Wei, H, Liu, Y, Wang, F, Fang, Q. | | 登録日 | 2024-09-13 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Near-atomic structures of RHDV reveal insights into capsid assembly and different conformations between mature virion and VLP
J.Virol.
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9JJJ
 | | Cryo-EM structure of a T=3 VLP of RHDV GI.2 | | 分子名称: | Capsid protein | | 著者 | Ruan, Z, Shao, Q, Song, Y, Hu, B, Fan, Z, Wei, H, Liu, Y, Wang, F, Fang, Q. | | 登録日 | 2024-09-13 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | | 主引用文献 | Near-atomic structures of RHDV reveal insights into capsid assembly and different conformations between mature virion and VLP
J.Virol.
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9JJG
 | | Cryo-EM structure of RHDV GI.2 virion | | 分子名称: | Genome polyprotein | | 著者 | Ruan, Z, Shao, Q, Song, Y, Hu, B, Fan, Z, Wei, H, Liu, Y, Wang, F, Fang, Q. | | 登録日 | 2024-09-13 | | 公開日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (2.46 Å) | | 主引用文献 | Near-atomic structures of RHDV reveal insights into capsid assembly and different conformations between mature virion and VLP
J.Virol., 2014
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