2GZ3
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![BU of 2gz3 by Molmil](/molmil-images/mine/2gz3) | Structure of Aspartate Semialdehyde Dehydrogenase (ASADH) from Streptococcus pneumoniae complexed with NADP and aspartate-semialdehyde | Descriptor: | (2R)-2-AMINO-4-OXOBUTANOIC ACID, Aspartate beta-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Faehnle, C.R, Le Coq, J, Liu, X, Viola, R.E. | Deposit date: | 2006-05-10 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria. J.Biol.Chem., 281, 2006
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5W0O
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5W0N
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![BU of 5w0n by Molmil](/molmil-images/mine/5w0n) | Structure of human TUT7 catalytic module (CM) in complex with UMPNPP and U2 RNA | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, IODIDE ION, MAGNESIUM ION, ... | Authors: | Faehnle, C.R, Walleshauser, J, Joshua-Tor, L. | Deposit date: | 2017-05-31 | Release date: | 2017-06-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.497 Å) | Cite: | Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis. Nat. Struct. Mol. Biol., 24, 2017
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4PMW
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![BU of 4pmw by Molmil](/molmil-images/mine/4pmw) | |
1YS4
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![BU of 1ys4 by Molmil](/molmil-images/mine/1ys4) | |
4KRE
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![BU of 4kre by Molmil](/molmil-images/mine/4kre) | |
4KRF
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![BU of 4krf by Molmil](/molmil-images/mine/4krf) | |
5W0M
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![BU of 5w0m by Molmil](/molmil-images/mine/5w0m) | Structure of human TUT7 catalytic module (CM) in complex with U5 RNA | Descriptor: | IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ... | Authors: | Faehnle, C.R, Walleshauser, J, Joshua-Tor, L. | Deposit date: | 2017-05-31 | Release date: | 2017-06-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.298 Å) | Cite: | Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis. Nat. Struct. Mol. Biol., 24, 2017
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5W0B
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![BU of 5w0b by Molmil](/molmil-images/mine/5w0b) | Structure of human TUT7 catalytic module (CM) | Descriptor: | IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ... | Authors: | Faehnle, C.R, Walleshauser, J, Joshua-Tor, L. | Deposit date: | 2017-05-30 | Release date: | 2017-06-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.614 Å) | Cite: | Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis. Nat. Struct. Mol. Biol., 24, 2017
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2GZ1
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![BU of 2gz1 by Molmil](/molmil-images/mine/2gz1) | Structure of Aspartate Semialdehyde Dehydrogenase (ASADH) from Streptococcus pneumoniae complexed with NADP | Descriptor: | Aspartate beta-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Faehnle, C.R, Le Coq, J, Liu, X, Viola, R.E. | Deposit date: | 2006-05-10 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria. J.Biol.Chem., 281, 2006
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2GZ2
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![BU of 2gz2 by Molmil](/molmil-images/mine/2gz2) | Structure of Aspartate Semialdehyde Dehydrogenase (ASADH) from Streptococcus pneumoniae complexed with 2',5'-ADP | Descriptor: | ADENOSINE-2'-5'-DIPHOSPHATE, Aspartate beta-semialdehyde dehydrogenase | Authors: | Faehnle, C.R, Le Coq, J, Liu, X, Viola, R.E. | Deposit date: | 2006-05-10 | Release date: | 2006-08-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria. J.Biol.Chem., 281, 2006
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2GYY
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![BU of 2gyy by Molmil](/molmil-images/mine/2gyy) | |
2HMF
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![BU of 2hmf by Molmil](/molmil-images/mine/2hmf) | |
5W6V
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2QZ9
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![BU of 2qz9 by Molmil](/molmil-images/mine/2qz9) | crystal structure of aspartate semialdehyde dehydrogenase II from vibrio cholerae | Descriptor: | Aspartate-semialdehyde dehydrogenase | Authors: | Viola, R.E, Liu, X, Ohren, J.F, Faehnle, C.R. | Deposit date: | 2007-08-16 | Release date: | 2008-04-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae. Acta Crystallogr.,Sect.D, 64, 2008
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2R00
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![BU of 2r00 by Molmil](/molmil-images/mine/2r00) | crystal structure of aspartate semialdehyde dehydrogenase II complexed with ASA from vibrio cholerae | Descriptor: | 2,2'-oxydiacetic acid, Aspartate-semialdehyde dehydrogenase | Authors: | Viola, R.E, Liu, X, Ohren, J.F, Faehnle, C.R. | Deposit date: | 2007-08-17 | Release date: | 2008-04-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae. Acta Crystallogr.,Sect.D, 64, 2008
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1PU2
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![BU of 1pu2 by Molmil](/molmil-images/mine/1pu2) | Crystal Structure of the K246R Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae | Descriptor: | Aspartate-semialdehyde dehydrogenase | Authors: | Blanco, J, Moore, R.A, Faehnle, C.R, Coe, D.M, Viola, R.E. | Deposit date: | 2003-06-23 | Release date: | 2004-07-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr.,Sect.D, 60, 2004
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1Q2X
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![BU of 1q2x by Molmil](/molmil-images/mine/1q2x) | Crystal Structure of the E243D Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae bound with substrate aspartate semialdehyde | Descriptor: | Aspartate-semialdehyde dehydrogenase | Authors: | Blanco, J, Moore, R.A, Faehnle, C.R, Coe, D.M, Viola, R.E. | Deposit date: | 2003-07-26 | Release date: | 2004-07-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr.,Sect.D, 60, 2004
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1PQP
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![BU of 1pqp by Molmil](/molmil-images/mine/1pqp) | Crystal Structure of the C136S Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae Bound with Aspartate Semialdehyde and Phosphate | Descriptor: | Aspartate-semialdehyde dehydrogenase, L-HOMOSERINE, PHOSPHATE ION | Authors: | Blanco, J, Moore, R.A, Faehnle, C.R, Viola, R.E. | Deposit date: | 2003-06-18 | Release date: | 2004-08-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr.,Sect.D, 60, 2004
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1PS8
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![BU of 1ps8 by Molmil](/molmil-images/mine/1ps8) | Crystal Structure of the R270K Mutant of Aspartate Semialdehyde dehydrogenase from Haemophilus influenzae | Descriptor: | Aspartate semialdehyde dehydrogenase | Authors: | Blanco, J, Moore, R.A, Faehnle, C.R, Coe, D.M, Viola, R.E. | Deposit date: | 2003-06-20 | Release date: | 2004-07-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr.,Sect.D, 60, 2004
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1PR3
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![BU of 1pr3 by Molmil](/molmil-images/mine/1pr3) | Crystal Structure of the R103K Mutant of Aspartate Semialdehyde dehydrogenase from Haemophilus influenzae | Descriptor: | Aspartate semialdehyde dehydrogenase, PHOSPHATE ION | Authors: | Blanco, J, Moore, R.A, Faehnle, C.R, Coe, D.M, Viola, R.E. | Deposit date: | 2003-06-19 | Release date: | 2004-07-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr.,Sect.D, 60, 2004
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3Q11
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![BU of 3q11 by Molmil](/molmil-images/mine/3q11) | Crystals Structure of Aspartate beta-Semialdehyde Dehydrogenase from Streptococcus pneumoniae with NADP and aspartyl beta-difluorophosphonate | Descriptor: | 1,2-ETHANEDIOL, 5,5-difluoro-4-oxo-5-phosphono-D-norvaline, Aspartate-semialdehyde dehydrogenase, ... | Authors: | Pavlovsky, A.G, Viola, R.E, Faehnle, C.R. | Deposit date: | 2010-12-16 | Release date: | 2012-01-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family. Chem.Biol.Drug Des., 79, 2012
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3PYL
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![BU of 3pyl by Molmil](/molmil-images/mine/3pyl) | Crystal structure of aspartate beta-semialdehide dehydrogenase from Streptococcus pneumoniae with D-2,3-diaminopropionate | Descriptor: | 3-amino-D-alanine, Aspartate-semialdehyde dehydrogenase | Authors: | Pavlovsky, A.G, Liu, X, Faehnle, C.R, Potente, N, Viola, R.E. | Deposit date: | 2010-12-13 | Release date: | 2012-01-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family. Chem.Biol.Drug Des., 79, 2012
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