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PDB: 234 件

6FZ2
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BU of 6fz2 by Molmil
Human N-myristoyltransferase (NMT1) with Myristoyl-CoA and inhibitor bound
分子名称: GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, MAGNESIUM ION, ...
著者Kersten, F.C, Brenk, R, Jaenicke, E.
登録日2018-03-13
公開日2019-03-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献How To Design Selective Ligands for Highly Conserved Binding Sites: A Case Study UsingN-Myristoyltransferases as a Model System.
J.Med.Chem., 63, 2020
7MWN
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BU of 7mwn by Molmil
An engineered PYL2-based WIN 55,212-2 synthetic cannabinoid sensor with a stabilized HAB1 variant
分子名称: ACETATE ION, Abscisic acid receptor PYL2, CHLORIDE ION, ...
著者Peterson, F.C, Beltran, J, Bedewitz, M, Steiner, P.J, Cutler, S.R, Whitehead, T.A.
登録日2021-05-17
公開日2022-06-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Rapid biosensor development using plant hormone receptors as reprogrammable scaffolds.
Nat.Biotechnol., 40, 2022
2GOV
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BU of 2gov by Molmil
Solution structure of Murine p22HBP
分子名称: Heme-binding protein 1
著者Volkman, B.F, Dias, J.S, Goodfellow, B.J, Peterson, F.C, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-04-14
公開日2006-05-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The First Structure from the SOUL/HBP Family of Heme-binding Proteins, Murine P22HBP.
J.Biol.Chem., 281, 2006
2GOW
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BU of 2gow by Molmil
Solution structure of BC059385 from Homo sapiens
分子名称: Ubiquitin-like protein 3
著者Volkman, B.F, de la Cruz, N.B, Lytle, B.L, Peterson, F.C, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-04-14
公開日2006-04-25
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of a membrane-anchored ubiquitin-fold (MUB) protein from Homo sapiens.
Protein Sci., 16, 2007
9COJ
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BU of 9coj by Molmil
SH3-like tandem domain of human KIN protein
分子名称: DNA/RNA-binding protein KIN17
著者de Lourenco, I.O, Fossey, M.A, Souza, F.P, Seixas, F.A.V, Fernandez, M.A, Almeida, F.C.L, Caruso, I.P.
登録日2024-07-16
公開日2024-07-31
実験手法SOLUTION NMR
主引用文献Solution structure of SH3-like tandem domain of human KIN protein and its interaction with RNA homo-oligonucleotides
To Be Published
1RY4
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BU of 1ry4 by Molmil
NMR Structure of the CRIB-PDZ module of Par-6
分子名称: CG5884-PA
著者Peterson, F.C, Penkert, R.R, Volkman, B.F, Prehoda, K.E.
登録日2003-12-19
公開日2004-03-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Cdc42 Regulates the Par-6 PDZ Domain through an Allosteric CRIB-PDZ Transition.
Mol.Cell, 13, 2004
6NOI
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BU of 6noi by Molmil
Crystal structure of Tsn15 in apo form
分子名称: DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, TRIETHYLENE GLYCOL, ...
著者Little, R, Paiva, F.C.R, Dias, M.V.B, Leadlay, P.
登録日2019-01-16
公開日2019-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Unexpected enzyme-catalysed [4+2] cycloaddition and rearrangement in polyether antibiotic biosynthesis
Nat Catal, 2019
6NNW
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BU of 6nnw by Molmil
Tsn15 in complex with substrate intermediate
分子名称: (3E)-3-{(1S,4S,4aS,5R,8aS)-1-[(2E,4R,7S,8E,10S)-1,7-dihydroxy-10-{(2R,3S,5R)-5-[(1S)-1-methoxyethyl]-3-methyloxolan-2-yl}-4-methylundeca-2,8-dien-2-yl]-4,5-dimethyloctahydro-3H-2-benzopyran-3-ylidene}oxolane-2,4-dione, PHOSPHATE ION, PROPANOIC ACID, ...
著者Paiva, F.C.R, Little, R, Leadlay, P, Dias, M.V.B.
登録日2019-01-15
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Unexpected enzyme-catalysed [4+2] cycloaddition and rearrangement in polyether antibiotic biosynthesis
Nat Catal, 2019
8WKF
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BU of 8wkf by Molmil
Rational Design of Highly Selective PDE5 inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
分子名称: 3-[2-[[5-chloranyl-2-[(3-fluorophenyl)methylamino]phenyl]methyl]-4-oxidanylidene-3~{H}-quinazolin-7-yl]prop-2-enoic acid, MAGNESIUM ION, ZINC ION, ...
著者Zhang, F.C, Huang, Y.Y.
登録日2023-09-27
公開日2024-10-02
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Rational Design of Highly Selective PDE5 inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
To Be Published
8WKG
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BU of 8wkg by Molmil
Rational Design of Highly Selective PDE5 inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
分子名称: (~{E})-3-[2-[(3-chlorophenyl)methyl]-4-oxidanylidene-3~{H}-quinazolin-7-yl]prop-2-enoic acid, MAGNESIUM ION, ZINC ION, ...
著者Zhang, F.C, Huang, Y.Y.
登録日2023-09-27
公開日2024-10-02
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Rational Design of Highly Selective PDE5 inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
To Be Published
1S4J
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BU of 1s4j by Molmil
NMR structure of cross-reactive peptides from Homo sapiens
分子名称: 60S acidic ribosomal protein P2
著者Soares, M.R, Bisch, P.M, Campos de Carvalho, A.C, Valente, A.P, Almeida, F.C.L.
登録日2004-01-16
公開日2004-03-16
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Correlation between conformation and antibody binding: NMR structure of cross-reactive peptides from T. cruzi, human and L. braziliensis
Febs Lett., 560, 2004
1RZX
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BU of 1rzx by Molmil
Crystal Structure of a Par-6 PDZ-peptide Complex
分子名称: Acetylated VKESLV Peptide, CG5884-PA
著者Peterson, F.C, Penkert, R.R, Volkman, F.B, Prehoda, K.E.
登録日2003-12-29
公開日2004-01-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Cdc42 regulates the Par-6 PDZ domain through an allosteric CRIB-PDZ transition.
Mol.Cell, 13, 2004
1SL3
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BU of 1sl3 by Molmil
crystal structue of Thrombin in complex with a potent P1 heterocycle-Aryl based inhibitor
分子名称: (2-[6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-YL)ETHYL]AMINO}-2-OXOPYRAZIN-1(2H)-YL]-N-[5-CHLORO-2-(1H-TETRAZOL-1-YL)BENZYL]ACETAMIDE, Hirudin, thrombin
著者Young, M.B, Barrow, J.C, Glass, K.L, Lundell, G.F, Newton, C.L, Pellicore, J.M, Rittle, K.E, Selnick, H.G, Stauffer, K.J, Vacca, J.P, Williams, P.D, Bohn, D, Clayton, F.C, Cook, J.J, Krueger, J.A, Kuo, L.C, Lewis, S.D, Lucas, B.J, McMasters, D.R, Miller-Stein, C, Pietrak, B.L.
登録日2004-03-05
公開日2004-08-03
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors
J.Med.Chem., 47, 2004
6NWC
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BU of 6nwc by Molmil
PYL10 bound to the ABA pan-agonist 3CB
分子名称: 1-{[(4-cyano-3-cyclopropylphenyl)acetyl]amino}cyclohexane-1-carboxylic acid, Abscisic acid receptor PYL10
著者Peterson, F.C, Vaidya, A, Jensen, D.R, Volkman, B.F, Cutler, S.R.
登録日2019-02-06
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Dynamic control of plant water use using designed ABA receptor agonists.
Science, 366, 2019
1SJG
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BU of 1sjg by Molmil
Solution Structure of T4moC, the Rieske Ferredoxin Component of the Toluene 4-Monooxygenase Complex
分子名称: FE2/S2 (INORGANIC) CLUSTER, Toluene-4-monooxygenase system protein C
著者Skjeldal, L, Peterson, F.C, Doreleijers, J.F, Moe, L.A, Pikus, J.D, Volkman, B.F, Westler, W.M, Markley, J.L, Fox, B.G.
登録日2004-03-03
公開日2004-09-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of T4moC, the Rieske ferredoxin component of the toluene 4-monooxygenase complex
J.Biol.Inorg.Chem., 9, 2004
6NOM
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BU of 6nom by Molmil
NMR solution structure of Pisum sativum defensin 2 (Psd2) provides evidence for the presence of hydrophobic surface clusters
分子名称: Defensin-2
著者Pinheiro-Aguiar, R, Amaral, V.S.G, Bastos, I, Kurtenbach, E, Almeida, F.C.L.
登録日2019-01-16
公開日2019-08-21
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Nuclear magnetic resonance solution structure of Pisum sativum defensin 2 provides evidence for the presence of hydrophobic surface-clusters.
Proteins, 88, 2020
6NAN
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BU of 6nan by Molmil
NMR structure determination of Ixolaris and Factor X interaction reveals a noncanonical mechanism of Kunitz inhibition
分子名称: Ixolaris
著者De Paula, V.S, Sgourakis, N.G, Francischetti, I.M.B, Almeida, F.C.L, Monteiro, R.Q, Valente, A.P.
登録日2018-12-06
公開日2019-06-12
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献NMR structure determination of Ixolaris and factor X(a) interaction reveals a noncanonical mechanism of Kunitz inhibition.
Blood, 134, 2019
1SE9
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BU of 1se9 by Molmil
Structure of At3g01050, a ubiquitin-fold protein from Arabidopsis thaliana
分子名称: ubiquitin family
著者Volkman, B.F, Lytle, B.L, Peterson, F.C, Center for Eukaryotic Structural Genomics (CESG)
登録日2004-02-16
公開日2004-02-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Cell-free protein production and labeling protocol for NMR-based structural proteomics.
Nat.Methods, 1, 2004
5SZW
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BU of 5szw by Molmil
NMR solution structure of the RRM1 domain of the post-transcriptional regulator HuR
分子名称: ELAV-like protein 1
著者Lixa, C, Mujo, A, Jendiroba, K.A, Almeida, F.C.L, Lima, L.M.T.R, Pinheiro, A.S.
登録日2016-08-15
公開日2017-09-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Oligomeric transition and dynamics of RNA binding by the HuR RRM1 domain in solution.
J. Biomol. NMR, 72, 2018
6NWB
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BU of 6nwb by Molmil
PYL10 bound to the selective agonist hexabactin
分子名称: Abscisic acid receptor PYL10, N-{[(4-cyanophenyl)methyl]sulfonyl}-1-(thiophen-3-yl)cyclohexane-1-carboxamide
著者Peterson, F.C, Vaidya, A, Jensen, D.R, Volkman, B.F, Cutler, S.R.
登録日2019-02-06
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献PYL10 bound to the selective agonist hexabactin
To Be Published
5UR6
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BU of 5ur6 by Molmil
PYR1 bound to the rationally designed agonist cyanabactin
分子名称: Abscisic acid receptor PYR1, N-(4-cyano-3-cyclopropylphenyl)-1-(4-methylphenyl)methanesulfonamide, SULFATE ION
著者Peterson, F.C, Vaidya, A, Jensen, D.R, Volkman, B.F, Cutler, S.R.
登録日2017-02-09
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.631 Å)
主引用文献A Rationally Designed Agonist Defines Subfamily IIIA Abscisic Acid Receptors As Critical Targets for Manipulating Transpiration.
ACS Chem. Biol., 12, 2017
5UR5
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BU of 5ur5 by Molmil
PYR1 bound to the rationally designed agonist 4m
分子名称: Abscisic acid receptor PYR1, GLYCEROL, N-(4-cyano-3-ethyl-5-methylphenyl)-1-(4-methylphenyl)methanesulfonamide, ...
著者Peterson, F.C, Vaidya, A, Jensen, D.R, Volkman, B.F, Cutler, S.R.
登録日2017-02-09
公開日2017-11-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A Rationally Designed Agonist Defines Subfamily IIIA Abscisic Acid Receptors As Critical Targets for Manipulating Transpiration.
ACS Chem. Biol., 12, 2017
5US5
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BU of 5us5 by Molmil
Solution structure of the IreB homodimer
分子名称: UPF0297 protein EF_1202
著者Lytle, B.L, Peterson, F.C, Volkman, B.F, Kristich, C.J, Center for Eukaryotic Structural Genomics (CESG)
登録日2017-02-13
公開日2017-06-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and Dimerization of IreB, a Negative Regulator of Cephalosporin Resistance in Enterococcus faecalis.
J. Mol. Biol., 429, 2017
5UR4
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1.5 A Crystal structure of PYR1 bound to Pyrabactin
分子名称: 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYR1, GLYCEROL
著者Peterson, F.C, Jensen, D.R, Volkman, B.F, Cutler, S.R.
登録日2017-02-09
公開日2018-01-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献1.5 A Crystal structure of PYR1 bound to Pyrabactin
To Be Published
5UR7
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Crystal structure of engineered CCL20 disulfide locked dimer
分子名称: ACETATE ION, C-C motif chemokine 20, ISOPROPYL ALCOHOL
著者Getschman, A.E, Peterson, F.C, Volkman, B.F.
登録日2017-02-09
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.0004 Å)
主引用文献Protein engineering of the chemokine CCL20 prevents psoriasiform dermatitis in an IL-23-dependent murine model.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

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件を2024-10-16に公開中

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