4B1W
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![BU of 4b1w by Molmil](/molmil-images/mine/4b1w) | Structure of the Phactr1 RPEL-2 domain bound to actin | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Mouilleron, S, Wiezlak, M, O'Reilly, N, Treisman, R, McDonald, N.Q. | Deposit date: | 2012-07-12 | Release date: | 2013-07-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity. Structure, 20, 2012
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4B1Z
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![BU of 4b1z by Molmil](/molmil-images/mine/4b1z) | Structure of the Phactr1 RPEL domain bound to G-actin | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Mouilleron, S, Wiezlak, M, O'Reilly, N, Treisman, R, McDonald, N.Q. | Deposit date: | 2012-07-12 | Release date: | 2012-11-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity. Structure, 20, 2012
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4AMV
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![BU of 4amv by Molmil](/molmil-images/mine/4amv) | |
4B1V
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![BU of 4b1v by Molmil](/molmil-images/mine/4b1v) | Structure of the Phactr1 RPEL-N domain bound to G-actin | Descriptor: | 1,2-ETHANEDIOL, ACTIN, ALPHA SKELETAL MUSCLE, ... | Authors: | Mouilleron, S, Wiezlak, M, O'Reilly, N, Treisman, R, McDonald, N.Q. | Deposit date: | 2012-07-12 | Release date: | 2012-11-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity. Structure, 20, 2012
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2V6U
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![BU of 2v6u by Molmil](/molmil-images/mine/2v6u) | |
2V6S
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![BU of 2v6s by Molmil](/molmil-images/mine/2v6s) | |
2V6T
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![BU of 2v6t by Molmil](/molmil-images/mine/2v6t) | Crystal structure of a complex of pterin-4a-carbinolamine dehydratase from Toxoplasma gondii with 7,8-dihydrobiopterin | Descriptor: | 2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE, PTERIN-4A-CARBINOLAMINE DEHYDRATASE | Authors: | Cameron, S, Fyffe, S.A, Hunter, W.N. | Deposit date: | 2007-07-20 | Release date: | 2008-07-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal Structures of Toxoplasma Gondii Pterin-4A-Carbinolamine Dehydratase and Comparisons with Mammalian and Parasite Orthologues. Mol.Biochem.Parasitol., 158, 2008
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2V51
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![BU of 2v51 by Molmil](/molmil-images/mine/2v51) | Structure of MAL-RPEL1 complexed to actin | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Mouilleron, S, Guettler, S, Langer, C.A, Treisman, R, McDonald, N.Q. | Deposit date: | 2008-10-01 | Release date: | 2008-11-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL. EMBO J., 27, 2008
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4B1X
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![BU of 4b1x by Molmil](/molmil-images/mine/4b1x) | Structure of the Phactr1 RPEL-2 bound to G-actin | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Mouilleron, S, Wiezlak, M, O'Reilly, N, Treisman, R, McDonald, N.Q. | Deposit date: | 2012-07-12 | Release date: | 2013-07-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity. Structure, 20, 2012
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4B1Y
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![BU of 4b1y by Molmil](/molmil-images/mine/4b1y) | Structure of the Phactr1 RPEL-3 bound to G-actin | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Mouilleron, S, Wiezlak, M, O'Reilly, N, Treisman, R, McDonald, N.Q. | Deposit date: | 2012-07-12 | Release date: | 2013-07-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity. Structure, 20, 2012
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4B1U
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![BU of 4b1u by Molmil](/molmil-images/mine/4b1u) | Structure of the Phactr1 RPEL domain and RPEL motif directed assemblies with G-actin reveal the molecular basis for actin binding cooperativity. | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACTIN, ALPHA SKELETAL MUSCLE, ... | Authors: | Mouilleron, S, Wiezlak, M, O'Reilly, N, Treisman, R, McDonald, N.Q. | Deposit date: | 2012-07-12 | Release date: | 2013-07-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity. Structure, 20, 2012
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2V52
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![BU of 2v52 by Molmil](/molmil-images/mine/2v52) | Structure of MAL-RPEL2 complexed to G-actin | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Mouilleron, S, Guettler, S, Langer, C.A, Treisman, R, McDonald, N.Q. | Deposit date: | 2008-10-01 | Release date: | 2008-11-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL. EMBO J., 27, 2008
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2V6I
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![BU of 2v6i by Molmil](/molmil-images/mine/2v6i) | Kokobera Virus Helicase | Descriptor: | PYROPHOSPHATE 2-, RNA HELICASE | Authors: | Speroni, S, De Colibus, L, Coutard, B, Canard, B, Mattevi, A. | Deposit date: | 2007-07-18 | Release date: | 2008-03-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and Biochemical Analysis of Kokobera Virus Helicase Proteins: Struct., Funct., Bioinf., 70, 2008
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2V6J
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![BU of 2v6j by Molmil](/molmil-images/mine/2v6j) | Kokobera Virus Helicase: Mutant Met47Thr | Descriptor: | RNA HELICASE | Authors: | Speroni, S, De Colibus, L, Coutard, B, Canard, B, Mattevi, A. | Deposit date: | 2007-07-18 | Release date: | 2008-03-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and Biochemical Analysis of Kokobera Virus Helicase Proteins: Struct., Funct., Bioinf., 70, 2008
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2VF5
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![BU of 2vf5 by Molmil](/molmil-images/mine/2vf5) | |
2W90
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![BU of 2w90 by Molmil](/molmil-images/mine/2w90) | Geobacillus stearothermophilus 6-phosphogluconate dehydrogenase with bound 6- phosphogluconate | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, ... | Authors: | Cameron, S, Martini, V.P, Iulek, J, Hunter, W.N. | Deposit date: | 2009-01-20 | Release date: | 2009-04-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Geobacillus Stearothermophilus 6-Phosphogluconate Dehydrogenase, Complexed with 6-Phosphogluconate. Acta Crystallogr.,Sect.F, 65, 2009
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2W8Z
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![BU of 2w8z by Molmil](/molmil-images/mine/2w8z) | Geobacillus stearothermophilus 6-phosphogluconate dehydrogenase with bound 6- phosphogluconate | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING, ... | Authors: | Cameron, S, Hunter, W.N. | Deposit date: | 2009-01-20 | Release date: | 2009-04-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Geobacillus Stearothermophilus 6-Phosphogluconate Dehydrogenase, Complexed with 6-Phosphogluconate. Acta Crystallogr.,Sect.F, 65, 2009
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2J6H
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![BU of 2j6h by Molmil](/molmil-images/mine/2j6h) | |
2VF4
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![BU of 2vf4 by Molmil](/molmil-images/mine/2vf4) | E. coli glucosamine-6-P synthase | Descriptor: | GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE | Authors: | Mouilleron, S, Golinelli-Pimpaneau, B. | Deposit date: | 2007-10-30 | Release date: | 2008-03-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Ordering of C-Terminal Loop and Glutaminase Domains of Glucosamine-6-Phosphate Synthase Promotes Sugar Ring Opening and Formation of the Ammonia Channel. J.Mol.Biol., 377, 2008
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5JWP
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![BU of 5jwp by Molmil](/molmil-images/mine/5jwp) | Crystal structure of human FIH D201E variant in complex with Zn, alpha-ketoglutarate, and HIF1 alpha peptide. | Descriptor: | 2-OXOGLUTARIC ACID, GLYCEROL, Hypoxia-inducible factor 1-alpha, ... | Authors: | Taabazuing, C.Y, Garman, S.C, Eron, S, Knapp, M.J. | Deposit date: | 2016-05-12 | Release date: | 2016-11-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The facial triad in the alpha-ketoglutarate dependent oxygenase FIH: A role for sterics in linking substrate binding to O2 activation. J.Inorg.Biochem., 166, 2016
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5JWK
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![BU of 5jwk by Molmil](/molmil-images/mine/5jwk) | Factor Inhibiting HIF D201E in Complex with Fe, and Alpha-Ketoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, DI(HYDROXYETHYL)ETHER, FE (II) ION, ... | Authors: | Taabazuing, C.Y, Garman, S.C, Knapp, M.J, Eron, S. | Deposit date: | 2016-05-12 | Release date: | 2017-05-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Factor Inhibiting HIF D201E in Complex with Fe, and Alpha-Ketoglutarate To Be Published
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5JWL
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![BU of 5jwl by Molmil](/molmil-images/mine/5jwl) | Factor Inhibiting HIF D201E in Complex with Zn, and Alpha-Ketoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, DI(HYDROXYETHYL)ETHER, Hypoxia-inducible factor 1-alpha inhibitor, ... | Authors: | Taabazuing, C.Y, Garman, S.C, Eron, S, Knapp, M.J. | Deposit date: | 2016-05-12 | Release date: | 2017-05-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Factor Inhibiting HIF D201E in Complex with Zn, and Alpha-Ketoglutarate To Be Published
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5UGF
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![BU of 5ugf by Molmil](/molmil-images/mine/5ugf) | Crystal structure of human purine nucleoside phosphorylase (F159Y) mutant complexed with DADMe-ImmG and phosphate | Descriptor: | 2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, PHOSPHATE ION, Purine nucleoside phosphorylase | Authors: | Harijan, R.K, Cameron, S.A, Bonanno, J.B, Almo, S.C, Schramm, V.L. | Deposit date: | 2017-01-08 | Release date: | 2017-06-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Catalytic-site design for inverse heavy-enzyme isotope effects in human purine nucleoside phosphorylase. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5FM3
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![BU of 5fm3 by Molmil](/molmil-images/mine/5fm3) | Crystal structure of hyper-phosphorylated RET kinase domain with (proximal) juxtamembrane segment | Descriptor: | 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET | Authors: | Plaza-Menacho, I, Barnouin, K, Barry, R, Borg, A, Orme, M, Mouilleron, S, Martinez-Torres, R.J, Meier, P, McDonald, N.Q. | Deposit date: | 2015-10-30 | Release date: | 2016-12-28 | Last modified: | 2019-04-24 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements. Cell Rep, 17, 2016
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7AA9
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![BU of 7aa9 by Molmil](/molmil-images/mine/7aa9) | Structure of SCOC pT13/pT15 LIR motif bound to GABARAPL1 | Descriptor: | Gamma-aminobutyric acid receptor-associated protein-like 1, pT13/PT15 SCOC LIR | Authors: | Lee, R, Mouilleron, S, Wirth, M, Zhang, W, O Reilly, N, Dhira, J, Tooze, S. | Deposit date: | 2020-09-03 | Release date: | 2021-06-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity. J.Mol.Biol., 433, 2021
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