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PDB: 14 件

4JFX
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Structure of phosphotyrosine (pTyr) scaffold bound to pTyr peptide
分子名称: Fab heavy chain, Fab light chain, Phosphopeptide, ...
著者Koerber, J.T, Thomsen, N.D, Hannigan, B.T, Degrado, W.F, Wells, J.A.
登録日2013-02-28
公開日2013-09-25
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Nature-inspired design of motif-specific antibody scaffolds.
Nat.Biotechnol., 31, 2013
4JFZ
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BU of 4jfz by Molmil
Structure of phosphoserine (pSAb) scaffold bound to pSer peptide
分子名称: Fab heavy chain, Fab light chain, PROPANOIC ACID, ...
著者Koerber, J.T, Thomsen, N.D, Hannigan, B.T, Degrado, W.F, Wells, J.A.
登録日2013-02-28
公開日2013-08-28
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Nature-inspired design of motif-specific antibody scaffolds.
Nat.Biotechnol., 31, 2013
4JG1
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Structure of phosphoserine/threonine (pSTAb) scaffold bound to pThr peptide
分子名称: Fab heavy chain, Fab light chain, PROPANOIC ACID, ...
著者Koerber, J.T, Thomsen, N.D, Hannigan, B.T, Degrado, W.F, Wells, J.A.
登録日2013-02-28
公開日2013-08-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Nature-inspired design of motif-specific antibody scaffolds.
Nat.Biotechnol., 31, 2013
4JFY
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Apo structure of phosphotyrosine (pYAb) scaffold
分子名称: Fab heavy chain, Fab light chain, TETRAETHYLENE GLYCOL
著者Koerber, J.T, Thomsen, N.D, Hannigan, B.T, Degrado, W.F, Wells, J.A.
登録日2013-02-28
公開日2013-08-28
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Nature-inspired design of motif-specific antibody scaffolds.
Nat.Biotechnol., 31, 2013
4JG0
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BU of 4jg0 by Molmil
Structure of phosphoserine/threonine (pSTAb) scaffold bound to pSer peptide
分子名称: Fab heavy chain, Fab light chain, PROPANOIC ACID, ...
著者Koerber, J.T, Thomsen, N.D, Hannigan, B.T, Degrado, W.F, Wells, J.A.
登録日2013-02-28
公開日2013-08-28
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Nature-inspired design of motif-specific antibody scaffolds.
Nat.Biotechnol., 31, 2013
6ESQ
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Structure of the acetoacetyl-CoA thiolase/HMG-CoA synthase complex from Methanothermococcus thermolithotrophicus soaked with acetyl-CoA
分子名称: CHLORIDE ION, COENZYME A, HydroxyMethylGlutaryl-CoA synthase, ...
著者Voegeli, B, Engilberge, S, Girard, E, Riobe, F, Maury, O, Erb, J.T, Shima, S, Wagner, T.
登録日2017-10-24
公開日2018-03-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Archaeal acetoacetyl-CoA thiolase/HMG-CoA synthase complex channels the intermediate via a fused CoA-binding site.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1HSK
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CRYSTAL STRUCTURE OF S. AUREUS MURB
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUCTASE
著者Benson, T.E, Harris, M.S, Choi, G.H, Cialdella, J.I, Herberg, J.T, Martin Jr, J.P, Baldwin, E.T.
登録日2000-12-27
公開日2001-03-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A structural variation for MurB: X-ray crystal structure of Staphylococcus aureus UDP-N-acetylenolpyruvylglucosamine reductase (MurB).
Biochemistry, 40, 2001
8EW6
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Anti-human CD8 VHH complex with CD8 alpha
分子名称: Anti-CD8 alpha VHH, T-cell surface glycoprotein CD8 alpha chain
著者Kiefer, J.R, Williams, S, Davies, C.W, Koerber, J.T, Sriraman, S.K, Yin, Y.P.
登録日2022-10-21
公開日2022-11-23
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.904 Å)
主引用文献Development of an 18 F-labeled anti-human CD8 VHH for same-day immunoPET imaging.
Eur J Nucl Med Mol Imaging, 50, 2023
7UVF
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Crystal structure of ZED8 Fab complex with CD8 alpha
分子名称: CHLORIDE ION, GLYCEROL, Immunoglobulin heavy chain, ...
著者Yu, C, Davies, C, Koerber, J.T, Williams, S.
登録日2022-05-01
公開日2022-10-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Preclinical development of ZED8, an 89 Zr immuno-PET reagent for monitoring tumor CD8 status in patients undergoing cancer immunotherapy.
Eur J Nucl Med Mol Imaging, 50, 2023
7U8G
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Cryo-EM structure of the core human NADPH oxidase NOX2
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7G5 - heavy chain, ...
著者Noreng, S, Ota, N, Sun, Y, Masureel, M, Payandeh, J, Yi, T, Koerber, J.T.
登録日2022-03-08
公開日2022-10-26
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of the core human NADPH oxidase NOX2.
Nat Commun, 13, 2022
6VVU
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Anti-Tryptase fab E104.v1 bound to tryptase
分子名称: CALCIUM ION, Fab E104.v1 heavy chain, Fab E104.v1 light chain, ...
著者Ultsch, M, Koerber, J.T.
登録日2020-02-18
公開日2020-12-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Bivalent antibody pliers inhibit beta-tryptase by an allosteric mechanism dependent on the IgG hinge.
Nat Commun, 11, 2020
2I8C
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Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies
分子名称: ADENOSINE-5'-DIPHOSPHATE, D-alanine-D-alanine ligase, MAGNESIUM ION, ...
著者Liu, S, Chang, J.S, Herberg, J.T, Horng, M, Tomich, P.K, Lin, A.H, Marotti, K.R.
登録日2006-09-01
公開日2006-09-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2I80
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Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies
分子名称: 3-CHLORO-2,2-DIMETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE, D-alanine-D-alanine ligase
著者Liu, S, Chang, J.S, Herberg, J.T, Horng, M.-M, Tomich, P.K, Lin, A.H, Marotti, K.R.
登録日2006-08-31
公開日2006-09-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2I87
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BU of 2i87 by Molmil
Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies
分子名称: D-alanine-D-alanine ligase, SULFATE ION
著者Liu, S, Chang, J.S, Herberg, J.T, Horng, M, Tomich, P.K, Lin, A.H, Marotti, K.R.
登録日2006-09-01
公開日2006-10-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Allosteric inhibition of Staphylococcus aureus D-alanine:D-alanine ligase revealed by crystallographic studies.
Proc.Natl.Acad.Sci.Usa, 103, 2006

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