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PDB: 42 件
6SAK
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BU of 6sak by Molmil
Structure of the OTULINcat C129A - SNX27 PDZ domain complex.
分子名称: GLYCEROL, SULFATE ION, Sorting nexin-27, ...
著者Elliott, P.R, Komander, D.
登録日2019-07-17
公開日2019-10-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Regulation of the endosomal SNX27-retromer by OTULIN.
Nat Commun, 10, 2019
7OWD
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BU of 7owd by Molmil
Structure of CYLD CAP-Gly3 (467-552) bound to Ub; tetragonal space group
分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase CYLD
著者Elliott, P.R, Komander, D.
登録日2021-06-17
公開日2021-10-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains.
Cell Rep, 37, 2021
7OWC
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BU of 7owc by Molmil
Structure of CYLD CAP-Gly3 (467-565) bound to Ub; orthorhobic space group
分子名称: Deubiquitinating enzyme CYLD, Ubiquitin-60S ribosomal protein L40
著者Elliott, P.R, Komander, D.
登録日2021-06-17
公開日2021-10-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains.
Cell Rep, 37, 2021
5OE7
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BU of 5oe7 by Molmil
Structure of OTULIN bound to the Met1-linked diubiquitin activity probe
分子名称: Polyubiquitin-C, Ubiquitin thioesterase otulin
著者Elliott, P.R, Komander, D.
登録日2017-07-07
公開日2017-09-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.
Cell Chem Biol, 24, 2017
3PV1
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BU of 3pv1 by Molmil
Crystal structure of the USP15 DUSP-UBL domains
分子名称: ACETATE ION, Ubiquitin carboxyl-terminal hydrolase 15
著者Elliott, P.R, Urbe, S, Clague, M.J, Barsukov, I.L.
登録日2010-12-06
公開日2011-11-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural variability of the ubiquitin specific protease DUSP-UBL double domains.
Febs Lett., 585, 2011
5LJM
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BU of 5ljm by Molmil
Structure of SPATA2 PUB domain
分子名称: GLYCEROL, Spermatogenesis-associated protein 2
著者Elliott, P.R, Komander, D.
登録日2016-07-18
公開日2016-08-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.454 Å)
主引用文献SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.
Mol.Cell, 63, 2016
5LJN
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BU of 5ljn by Molmil
Structure of the HOIP PUB domain bound to SPATA2 PIM peptide
分子名称: E3 ubiquitin-protein ligase RNF31, GLYCEROL, SULFATE ION, ...
著者Elliott, P.R, Komander, D.
登録日2016-07-18
公開日2016-08-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.
Mol.Cell, 63, 2016
3IVF
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BU of 3ivf by Molmil
Crystal structure of the talin head FERM domain
分子名称: Talin-1
著者Elliott, P.R, Goult, B.T, Bate, N, Grossmann, J.G, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L.
登録日2009-09-01
公開日2010-08-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献The Structure of the talin head reveals a novel extended conformation of the FERM domain
Structure, 18, 2010
4OYK
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BU of 4oyk by Molmil
Structure of HOIP PUB domain bound to OTULIN PIM
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase RNF31, Ubiquitin thioesterase otulin
著者Elliott, P.R, Komander, D.
登録日2014-02-12
公開日2014-05-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.0001 Å)
主引用文献Molecular Basis and Regulation of OTULIN-LUBAC Interaction.
Mol.Cell, 54, 2014
4OYJ
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BU of 4oyj by Molmil
Structure of the apo HOIP PUB domain
分子名称: E3 ubiquitin-protein ligase RNF31, SULFATE ION
著者Elliott, P.R, Komander, D.
登録日2014-02-12
公開日2014-05-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular Basis and Regulation of OTULIN-LUBAC Interaction.
Mol.Cell, 54, 2014
4A3P
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BU of 4a3p by Molmil
Structure of USP15 DUSP-UBL deletion mutant
分子名称: ACETATE ION, IODIDE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15
著者Elliott, P.R, Liu, H, Pastok, M.W, Grossmann, G.J, Rigden, D.J, Clague, M.J, Urbe, S, Barsukov, I.L.
登録日2011-10-03
公開日2011-11-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains.
FEBS Lett., 585, 2011
4A3O
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BU of 4a3o by Molmil
Crystal structure of the USP15 DUSP-UBL monomer
分子名称: GLYCEROL, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15
著者Elliott, P.R, Liu, H, Pastok, M.W, Grossmann, G.J, Rigden, D.J, Clague, M.J, Urbe, S, Barsukov, I.L.
登録日2011-10-03
公開日2011-11-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Variability of the Ubiquitin Specific Protease Dusp-Ubl Double Domains.
FEBS Lett., 585, 2011
1QLP
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BU of 1qlp by Molmil
2.0 ANGSTROM STRUCTURE OF INTACT ALPHA-1-ANTITRYPSIN: A CANONICAL TEMPLATE FOR ACTIVE SERPINS
分子名称: ALPHA-1-ANTITRYPSIN
著者Elliott, P.R, Pei, X.Y, Dafforn, T, Read, R.J, Carrell, R.W, Lomas, D.A.
登録日1999-09-10
公開日1999-09-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Topography of a 2.0 A structure of alpha1-antitrypsin reveals targets for rational drug design to prevent conformational disease.
Protein Sci., 9, 2000
6YIH
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BU of 6yih by Molmil
Structure of Chromosomal Passenger Complex (CPC) bound to phosphorylated Histone 3 peptide at 2.6 A.
分子名称: Baculoviral IAP repeat-containing protein 5, Borealin, Histone H3.1, ...
著者Serena, M, Elliott, P.R, Barr, F.A.
登録日2020-04-01
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle.
J.Cell Biol., 219, 2020
6YIP
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BU of 6yip by Molmil
Structure of MKLP2 coiled coil
分子名称: ISOPROPYL ALCOHOL, Kinesin-like protein KIF20A
著者Serena, M, Elliott, P.R, Barr, F.A.
登録日2020-04-01
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle.
J.Cell Biol., 219, 2020
8ATM
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BU of 8atm by Molmil
Structure of the giant inhibitor of apoptosis, BIRC6 (composite map)
分子名称: Baculoviral IAP repeat-containing protein 6
著者Dietz, L, Elliott, P.R.
登録日2022-08-23
公開日2023-03-08
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6.
Science, 379, 2023
8ATO
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BU of 8ato by Molmil
Structure of the giant inhibitor of apoptosis, BIRC6 bound to the regulator SMAC
分子名称: Baculoviral IAP repeat-containing protein 6, Diablo IAP-binding mitochondrial protein
著者Dietz, L, Elliott, P.R.
登録日2022-08-23
公開日2023-03-08
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6.
Science, 379, 2023
6I9C
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BU of 6i9c by Molmil
Structure of the OTU domain of OTULIN G281R mutant
分子名称: CHLORIDE ION, GLYCEROL, Ubiquitin thioesterase otulin
著者Damgaard, R.B, Elliott, P.R, Swatek, K.N, Maher, E.R, Stepensky, P, Elpeleg, O, Komander, D, Berkun, Y.
登録日2018-11-22
公開日2019-03-06
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献OTULIN deficiency in ORAS causes cell type-specific LUBAC degradation, dysregulated TNF signalling and cell death.
Embo Mol Med, 11, 2019
8P5P
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BU of 8p5p by Molmil
Structure of TECPR1 N-terminal DysF domain
分子名称: GLYCEROL, Tectonin beta-propeller repeat-containing protein 1
著者Boyle, K.B, Elliott, P.R, Randow, F.
登録日2023-05-24
公開日2023-07-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献TECPR1 conjugates LC3 to damaged endomembranes upon detection of sphingomyelin exposure.
Embo J., 42, 2023
6YIE
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BU of 6yie by Molmil
Structure of a Borealin-INCENP-Survivin complex
分子名称: Baculoviral IAP repeat-containing protein 5, Borealin, Inner centromere protein, ...
著者Serena, M, Elliott, P.R, Barr, F.A.
登録日2020-04-01
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle.
J.Cell Biol., 219, 2020
6YIF
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BU of 6yif by Molmil
Structure of Chromosomal Passenger Complex (CPC) bound to phosphorylated Histone 3 peptide at 1.8 A.
分子名称: Baculoviral IAP repeat-containing protein 5, Borealin, Inner centromere protein, ...
著者Serena, M, Elliott, P.R, Barr, F.A.
登録日2020-04-01
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle.
J.Cell Biol., 219, 2020
5LRV
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BU of 5lrv by Molmil
Structure of Cezanne/OTUD7B OTU domain bound to Lys11-linked diubiquitin
分子名称: GLYCEROL, OTU domain-containing protein 7B, PHOSPHATE ION, ...
著者Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D.
登録日2016-08-22
公開日2016-10-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016
5LRW
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BU of 5lrw by Molmil
Structure of Cezanne/OTUD7B OTU domain bound to ubiquitin
分子名称: GLYCEROL, OTU domain-containing protein 7B, Polyubiquitin-B
著者Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D.
登録日2016-08-22
公開日2016-10-19
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016
5LRX
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BU of 5lrx by Molmil
Structure of A20 OTU domain bound to ubiquitin
分子名称: Polyubiquitin-B, Tumor necrosis factor alpha-induced protein 3
著者Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D.
登録日2016-08-22
公開日2016-10-19
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016
5LRU
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BU of 5lru by Molmil
Structure of Cezanne/OTUD7B OTU domain
分子名称: OTU domain-containing protein 7B
著者Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D.
登録日2016-08-22
公開日2016-10-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.
Nature, 538, 2016

 

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