3UTD
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![BU of 3utd by Molmil](/molmil-images/mine/3utd) | Ec_IspH in complex with 4-oxopentyl diphosphate | 分子名称: | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4-oxopentyl trihydrogen diphosphate, FE3-S4 CLUSTER | 著者 | Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Schulz, C, Oldfield, E, Groll, M. | 登録日 | 2011-11-25 | 公開日 | 2012-09-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of acetylene hydratase activity of the iron-sulphur protein IspH. Nat Commun, 3, 2012
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3UV7
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![BU of 3uv7 by Molmil](/molmil-images/mine/3uv7) | Ec_IspH in complex with buta-2,3-dienyl diphosphate (1300) | 分子名称: | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER, buta-2,3-dien-1-yl trihydrogen diphosphate | 著者 | Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Schulz, C, Oldfield, E, Groll, M. | 登録日 | 2011-11-29 | 公開日 | 2012-09-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Discovery of acetylene hydratase activity of the iron-sulphur protein IspH. Nat Commun, 3, 2012
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3UV3
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![BU of 3uv3 by Molmil](/molmil-images/mine/3uv3) | Ec_IspH in complex with but-2-ynyl diphosphate (1086) | 分子名称: | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER, but-2-yn-1-yl trihydrogen diphosphate | 著者 | Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Schulz, C, Oldfield, E, Groll, M. | 登録日 | 2011-11-29 | 公開日 | 2012-09-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Discovery of acetylene hydratase activity of the iron-sulphur protein IspH. Nat Commun, 3, 2012
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3URK
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![BU of 3urk by Molmil](/molmil-images/mine/3urk) | IspH in complex with propynyl diphosphate (1061) | 分子名称: | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER, prop-2-yn-1-yl trihydrogen diphosphate | 著者 | Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Schulz, C, Oldfield, E, Groll, M. | 登録日 | 2011-11-22 | 公開日 | 2012-09-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Discovery of acetylene hydratase activity of the iron-sulphur protein IspH. Nat Commun, 3, 2012
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3UTC
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![BU of 3utc by Molmil](/molmil-images/mine/3utc) | Ec_IspH in complex with (E)-4-hydroxybut-3-enyl diphosphate | 分子名称: | (3E)-4-hydroxybut-3-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER | 著者 | Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Li, K, Schulz, C, Oldfield, E, Groll, M. | 登録日 | 2011-11-25 | 公開日 | 2012-09-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of acetylene hydratase activity of the iron-sulphur protein IspH. Nat Commun, 3, 2012
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1W77
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![BU of 1w77 by Molmil](/molmil-images/mine/1w77) | 2C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD) from Arabidopsis thaliana | 分子名称: | 2C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CADMIUM ION, COPPER (II) ION, ... | 著者 | Gabrielsen, M, Kaiser, J, Rohdich, F, Eisenreich, W, Bacher, A, Bond, C.S, Hunter, W.N. | 登録日 | 2004-08-30 | 公開日 | 2006-02-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Crystal Structure of a Plant 2C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase Exhibits a Distinct Quaternary Structure Compared to Bacterial Homologues and a Possible Role in Feedback Regulation for Cytidine Monophosphate. FEBS J., 273, 2006
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3UV6
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![BU of 3uv6 by Molmil](/molmil-images/mine/3uv6) | Ec_IspH in complex with 4-hydroxybutyl diphosphate (1301) | 分子名称: | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4-hydroxybutyl trihydrogen diphosphate, IRON/SULFUR CLUSTER | 著者 | Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Schulz, C, Oldfield, E, Groll, M. | 登録日 | 2011-11-29 | 公開日 | 2012-09-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of acetylene hydratase activity of the iron-sulphur protein IspH. Nat Commun, 3, 2012
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3UWM
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![BU of 3uwm by Molmil](/molmil-images/mine/3uwm) | Ec_IspH in complex with 4-oxobutyl diphosphate (1302) | 分子名称: | (3E)-4-hydroxybut-3-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4-oxobutyl trihydrogen diphosphate, ... | 著者 | Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Schulz, C, Oldfield, E, Groll, M. | 登録日 | 2011-12-02 | 公開日 | 2012-09-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of acetylene hydratase activity of the iron-sulphur protein IspH. Nat Commun, 3, 2012
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3F7T
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![BU of 3f7t by Molmil](/molmil-images/mine/3f7t) | Structure of active IspH shows a novel fold with a [3Fe-4S] cluster in the catalytic centre | 分子名称: | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, FE3-S4 CLUSTER, PHOSPHATE ION, ... | 著者 | Graewert, T, Eppinger, J, Rohdich, F, Bacher, A, Eisenreich, W, Groll, M. | 登録日 | 2008-11-10 | 公開日 | 2009-07-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of active IspH enzyme from Escherichia coli provides mechanistic insights into substrate reduction. Angew.Chem.Int.Ed.Engl., 48, 2009
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4H4E
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![BU of 4h4e by Molmil](/molmil-images/mine/4h4e) | IspH in complex with (E)-4-mercapto-3-methylbut-2-enyl diphosphate | 分子名称: | (2E)-3-methyl-4-sulfanylbut-2-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER | 著者 | Span, I, Eisenreich, W, Jauch, J, Bacher, A, Groll, M. | 登録日 | 2012-09-17 | 公開日 | 2013-01-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structures of Fluoro, Amino, and Thiol Inhibitors Bound to the [Fe(4) S(4) ] Protein IspH. Angew.Chem.Int.Ed.Engl., 52, 2013
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1JY8
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![BU of 1jy8 by Molmil](/molmil-images/mine/1jy8) | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) | 分子名称: | 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, CYTIDINE-5'-MONOPHOSPHATE, ... | 著者 | Steinbacher, S, Kaiser, J, Wungsintaweekul, J, Hecht, S, Eisenreich, W, Gerhardt, S, Bacher, A, Rohdich, F. | 登録日 | 2001-09-11 | 公開日 | 2002-01-30 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids. J.Mol.Biol., 316, 2002
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4H4D
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![BU of 4h4d by Molmil](/molmil-images/mine/4h4d) | IspH in complex with (E)-4-amino-3-methylbut-2-enyl diphosphate | 分子名称: | (2E)-4-amino-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER | 著者 | Span, I, Eisenreich, W, Jauch, J, Bacher, A, Groll, M. | 登録日 | 2012-09-17 | 公開日 | 2013-01-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structures of Fluoro, Amino, and Thiol Inhibitors Bound to the [Fe(4) S(4) ] Protein IspH. Angew.Chem.Int.Ed.Engl., 52, 2013
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4H4C
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![BU of 4h4c by Molmil](/molmil-images/mine/4h4c) | IspH in complex with (E)-4-fluoro-3-methylbut-2-enyl diphosphate | 分子名称: | (2E)-4-fluoro-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER | 著者 | Span, I, Eisenreich, W, Jauch, J, Bacher, A, Groll, M. | 登録日 | 2012-09-17 | 公開日 | 2013-01-23 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structures of Fluoro, Amino, and Thiol Inhibitors Bound to the [Fe(4) S(4) ] Protein IspH. Angew.Chem.Int.Ed.Engl., 52, 2013
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1KZL
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![BU of 1kzl by Molmil](/molmil-images/mine/1kzl) | Riboflavin Synthase from S.pombe bound to Carboxyethyllumazine | 分子名称: | 3-[8-((2S,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL)-2,4,7-TRIOXO-1,3,8-TRIHYDROPTERIDIN-6-YL]PROPANOIC ACID, MERCURY (II) ION, Riboflavin Synthase | 著者 | Gerhardt, S, Schott, A.K, Kairies, N, Cushman, M, Illarionov, B, Eisenreich, W, Bacher, A, Huber, R, Steinbacher, S, Fischer, M. | 登録日 | 2002-02-07 | 公開日 | 2002-11-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Studies on the Reaction Mechanism of Riboflavin Synthase; X-Ray Crystal Structure of a Complex with 6-Carboxyethyl-7-Oxo-8-Ribityllumazine STRUCTURE, 10, 2002
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2B99
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![BU of 2b99 by Molmil](/molmil-images/mine/2b99) | Crystal Structure of an archaeal pentameric riboflavin synthase Complex with a Substrate analog inhibitor | 分子名称: | 6,7-DIOXO-5H-8-RIBITYLAMINOLUMAZINE, Riboflavin synthase | 著者 | Ramsperger, A, Augustin, M, Schott, A.K, Gerhardt, S, Krojer, T, Eisenreich, W, Illarionov, B, Cushman, M, Bacher, A, Huber, R, Fischer, M. | 登録日 | 2005-10-11 | 公開日 | 2005-11-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Crystal Structure of an Archaeal Pentameric Riboflavin Synthase in Complex with a Substrate Analog Inhibitor: stereochemical implications J.Biol.Chem., 281, 2006
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2B98
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![BU of 2b98 by Molmil](/molmil-images/mine/2b98) | Crystal Structure of an archaeal pentameric riboflavin synthase | 分子名称: | Riboflavin synthase | 著者 | Ramsperger, A, Augustin, M, Schott, A.K, Gerhardt, S, Krojer, T, Eisenreich, W, Illarionov, B, Cushman, M, Bacher, A, Huber, R, Fischer, M. | 登録日 | 2005-10-11 | 公開日 | 2005-11-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of an Archaeal Pentameric Riboflavin Synthase in Complex with a Substrate Analog Inhibitor: stereochemical implications J.Biol.Chem., 281, 2006
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3KEF
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![BU of 3kef by Molmil](/molmil-images/mine/3kef) | Crystal structure of IspH:DMAPP-complex | 分子名称: | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, DIMETHYLALLYL DIPHOSPHATE, FE3-S4 CLUSTER | 著者 | Groll, M, Graewert, T, Span, I, Eisenreich, W, Bacher, A. | 登録日 | 2009-10-26 | 公開日 | 2010-01-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Probing the reaction mechanism of IspH protein by x-ray structure analysis. Proc.Natl.Acad.Sci.USA, 107, 2010
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3KEM
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![BU of 3kem by Molmil](/molmil-images/mine/3kem) | Crystal structure of IspH:IPP complex | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, FE3-S4 CLUSTER | 著者 | Groll, M, Graewert, T, Span, I, Eisenreich, W, Bacher, A. | 登録日 | 2009-10-26 | 公開日 | 2010-01-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Probing the reaction mechanism of IspH protein by x-ray structure analysis. Proc.Natl.Acad.Sci.USA, 107, 2010
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3KE9
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![BU of 3ke9 by Molmil](/molmil-images/mine/3ke9) | Crystal structure of IspH:Intermediate-complex | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER | 著者 | Groll, M, Graewert, T, Span, I, Eisenreich, W, Bacher, A. | 登録日 | 2009-10-24 | 公開日 | 2010-01-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Probing the reaction mechanism of IspH protein by x-ray structure analysis. Proc.Natl.Acad.Sci.USA, 107, 2010
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3KEL
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![BU of 3kel by Molmil](/molmil-images/mine/3kel) | Crystal Structure of IspH:PP complex | 分子名称: | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, FE3-S4 CLUSTER, PYROPHOSPHATE 2- | 著者 | Groll, M, Graewert, T, Span, I, Eisenreich, W, Bacher, A. | 登録日 | 2009-10-26 | 公開日 | 2010-01-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Probing the reaction mechanism of IspH protein by x-ray structure analysis. Proc.Natl.Acad.Sci.USA, 107, 2010
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3KE8
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![BU of 3ke8 by Molmil](/molmil-images/mine/3ke8) | Crystal structure of IspH:HMBPP-complex | 分子名称: | 4-HYDROXY-3-METHYL BUTYL DIPHOSPHATE, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER | 著者 | Groll, M, Graewert, T, Span, I, Eisenreich, W, Bacher, A. | 登録日 | 2009-10-24 | 公開日 | 2010-01-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Probing the reaction mechanism of IspH protein by x-ray structure analysis. Proc.Natl.Acad.Sci.USA, 107, 2010
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1U43
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![BU of 1u43 by Molmil](/molmil-images/mine/1u43) | IspF with 4-diphosphocytidyl-2c-methyl-D-erythritol 2-phosphate | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL 2-PHOSPHATE | 著者 | Steinbacher, S, Kaiser, J, Wungsintaweekul, J, Hecht, S, Eisenreich, W, Gerhardt, S, Bacher, A, Rohdich, F. | 登録日 | 2004-07-23 | 公開日 | 2004-08-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase Involved in Mevalonate Independent Biosynthesis of Isoprenoids J.Mol.Biol., 316, 2002
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1U3P
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![BU of 1u3p by Molmil](/molmil-images/mine/1u3p) | IspF native | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION | 著者 | Steinbacher, S, Kaiser, J, Wungsintaweekul, J, Hecht, S, Eisenreich, W, Gerhardt, S, Bacher, A, Rohdich, F. | 登録日 | 2004-07-22 | 公開日 | 2004-08-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structure of 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase Involved in Mevalonate Independent Biosynthesis of Isoprenoids J.Mol.Biol., 316, 2002
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1U40
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![BU of 1u40 by Molmil](/molmil-images/mine/1u40) | IspF with 4-diphosphocytidyl-2C-methyl-D-erythritol | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, ZINC ION | 著者 | Steinbacher, S, Kaiser, J, Wungsintaweekul, J, Hecht, S, Eisenreich, W, Gerhardt, S, Bacher, A, Rohdich, F. | 登録日 | 2004-07-23 | 公開日 | 2004-08-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase Involved in Mevalonate Independent Biosynthesis of Isoprenoids J.Mol.Biol., 316, 2002
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1U3L
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![BU of 1u3l by Molmil](/molmil-images/mine/1u3l) | IspF with Mg and CDP | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Steinbacher, S, Kaiser, J, Wungsintaweekul, J, Hechst, S, Eisenreich, W, Gerhardt, S, Bacher, A, Rohdich, F. | 登録日 | 2004-07-22 | 公開日 | 2004-08-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase Involved in Mevalonate Independent Biosynthesis of Isoprenoids J.Mol.Biol., 316, 2002
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