4H4D

IspH in complex with (E)-4-amino-3-methylbut-2-enyl diphosphate

Summary for 4H4D

• Entry DOI: 10.2210/pdb4h4d/pdb
• Related: 3DNF 3F7T 3KE8 4H4C 4H4E
• Descriptor: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER, (2E)-4-amino-3-methylbut-2-en-1-yl trihydrogen diphosphate, ... (4 entities in total)
• Functional Keywords: iron-sulfur protein, reductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 72576.35

Authors

Span, I.,Eisenreich, W.,Jauch, J.,Bacher, A.,Groll, M. (deposition date: 2012-09-17, release date: 2013-01-23, Last modification date: 2023-09-20)

• Primary citation: Span, I.,Wang, K.,Wang, W.,Jauch, J.,Eisenreich, W.,Bacher, A.,Oldfield, E.,Groll, M.; Structures of Fluoro, Amino, and Thiol Inhibitors Bound to the [Fe(4) S(4) ] Protein IspH.; Angew.Chem.Int.Ed.Engl., 52:2118-2121, 2013; PubMed: 23307751; DOI: 10.1002/anie.201208469

Experimental method

X-RAY DIFFRACTION (1.35 Å)