4H4C
IspH in complex with (E)-4-fluoro-3-methylbut-2-enyl diphosphate
Summary for 4H4C
Entry DOI | 10.2210/pdb4h4c/pdb |
Related | 3DNF 3F7T 3KE8 4H4D 4H4E |
Descriptor | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER, (2E)-4-fluoro-3-methylbut-2-en-1-yl trihydrogen diphosphate, ... (4 entities in total) |
Functional Keywords | iron-sulfur protein, reductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 72582.30 |
Authors | Span, I.,Eisenreich, W.,Jauch, J.,Bacher, A.,Groll, M. (deposition date: 2012-09-17, release date: 2013-01-23, Last modification date: 2023-09-20) |
Primary citation | Span, I.,Wang, K.,Wang, W.,Jauch, J.,Eisenreich, W.,Bacher, A.,Oldfield, E.,Groll, M. Structures of Fluoro, Amino, and Thiol Inhibitors Bound to the [Fe(4) S(4) ] Protein IspH. Angew.Chem.Int.Ed.Engl., 52:2118-2121, 2013 Cited by PubMed: 23307751DOI: 10.1002/anie.201208469 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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