Crystal structure of IspH:HMBPP-complex

Summary for 3KE8

Related3F7T 3DNF 3KE9 3KEF 3KEL 3KEM
Descriptor4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER, 4-HYDROXY-3-METHYL BUTYL DIPHOSPHATE, ... (4 entities in total)
Functional Keywordsinduced fit mechanism, fs4-iron-sulfure-cluster, iron, iron-sulfur, isoprene biosynthesis, metal-binding, nadp, oxidoreductase
Biological sourceEscherichia coli
Total number of polymer chains2
Total molecular weight73389.3
Groll, M.,Graewert, T.,Span, I.,Eisenreich, W.,Bacher, A. (deposition date: 2009-10-24, release date: 2010-01-12, Last modification date: 2013-12-04)
Primary citation
Grawert, T.,Span, I.,Eisenreich, W.,Rohdich, F.,Eppinger, J.,Bacher, A.,Groll, M.
Probing the reaction mechanism of IspH protein by x-ray structure analysis.
Proc.Natl.Acad.Sci.USA, 107:1077-1081, 2010
PubMed: 20080550 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.0913045107
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2371604.1%7.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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