5HGE
| Filamentous Assembly of Green Fluorescent Protein Supported by a C-terminal fusion of 18-residues, viewed in space group P212121 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Green fluorescent protein | Authors: | Sawaya, M.R, Heller, D.M, McPartland, L, Hochschild, A, Eisenberg, D.S. | Deposit date: | 2016-01-08 | Release date: | 2017-01-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.863 Å) | Cite: | Green Fluorescent Protein Fusion that Self Assembles as Polar Filaments to be published
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6N37
| SegA-sym, conformation of TDP-43 low complexity domain segment A sym | Descriptor: | TAR DNA-binding protein 43 | Authors: | Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2018-11-14 | Release date: | 2019-06-26 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nat.Struct.Mol.Biol., 26, 2019
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6N3C
| SegB, conformation of TDP-43 low complexity domain segment A | Descriptor: | TAR DNA-binding protein 43 | Authors: | Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2018-11-14 | Release date: | 2019-06-26 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nat.Struct.Mol.Biol., 26, 2019
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5HW9
| Filamentous Assembly of Green Fluorescent Protein Supported by a C-terminal fusion of 18-residues, viewed in space group P21 | Descriptor: | Green fluorescent protein | Authors: | Sawaya, M.R, Heller, D.M, McPartland, L, Hochschild, A, Eisenberg, D.S. | Deposit date: | 2016-01-29 | Release date: | 2017-02-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Green Fluorescent Protein Fusion that Self Assembles as Polar Filaments to be published
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5HBD
| Filamentous Assembly of Green Fluorescent Protein Supported by a C-terminal fusion of 18-residues, viewed in space group C2 | Descriptor: | Green fluorescent protein | Authors: | Sawaya, M.R, Hochschild, A, Heller, D.M, McPartland, L, Eisenberg, D.S. | Deposit date: | 2015-12-31 | Release date: | 2017-01-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Green Fluorescent Protein Fusion that Self Assembles as Polar Filaments to be published
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6N3B
| SegA-asym, conformation of TDP-43 low complexity domain segment A asym | Descriptor: | TAR DNA-binding protein 43 | Authors: | Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | Deposit date: | 2018-11-14 | Release date: | 2019-06-26 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nat.Struct.Mol.Biol., 26, 2019
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1HTO
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3LOZ
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4M5T
| Disulfide trapped human alphaB crystallin core domain in complex with C-terminal peptide | Descriptor: | Alpha-crystallin B chain, SULFATE ION | Authors: | Laganowsky, A, Cascio, D, Hochberg, G, Sawaya, M.R, Benesch, J.L.P, Robinson, C.V, Eisenberg, D. | Deposit date: | 2013-08-08 | Release date: | 2014-04-09 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity. Proc.Natl.Acad.Sci.USA, 111, 2014
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2APQ
| Crystal Structure of an Active Site Mutant of Bovine Pancreatic Ribonuclease A (H119A-RNase A) with a 10-Glutamine expansion in the C-terminal hinge-loop. | Descriptor: | PHOSPHATE ION, Ribonuclease | Authors: | Sambashivan, S, Liu, Y, Sawaya, M.R, Gingery, M, Eisenberg, D. | Deposit date: | 2005-08-16 | Release date: | 2005-09-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure. Nature, 437, 2005
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3DMK
| Crystal structure of Down Syndrome Cell Adhesion Molecule (DSCAM) isoform 1.30.30, N-terminal eight Ig domains | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Down Syndrome Cell Adhesion Molecule (DSCAM) isoform 1.30.30, ... | Authors: | Sawaya, M.R, Wojtowicz, W.M, Eisenberg, D, Zipursky, S.L. | Deposit date: | 2008-07-01 | Release date: | 2008-10-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (4.19 Å) | Cite: | A double S shape provides the structural basis for the extraordinary binding specificity of Dscam isoforms. Cell(Cambridge,Mass.), 134, 2008
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1U5H
| Structure of Citrate Lyase beta subunit from Mycobacterium tuberculosis | Descriptor: | FORMIC ACID, citE | Authors: | Goulding, C.W, Lekin, T, Kim, C.Y, Segelke, B, Terwilliger, T.C, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2004-07-27 | Release date: | 2004-10-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function. J.Mol.Biol., 365, 2007
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4M5S
| Human alphaB crystallin core domain in complex with C-terminal peptide | Descriptor: | Alpha-crystallin B chain, SUCCINIC ACID | Authors: | Laganowsky, A, Cascio, D, Sawaya, M.R, Eisenberg, D. | Deposit date: | 2013-08-08 | Release date: | 2014-04-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity. Proc.Natl.Acad.Sci.USA, 111, 2014
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5E5X
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5E5Z
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4MJH
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1G6U
| CRYSTAL STRUCTURE OF A DOMAIN SWAPPED DIMER | Descriptor: | DOMAIN SWAPPED DIMER, SULFATE ION, trifluoroacetic acid | Authors: | Ogihara, N.L, Ghirlanda, G, Bryson, J.W, Gingery, M, DeGrado, W.F, Eisenberg, D. | Deposit date: | 2000-11-07 | Release date: | 2001-02-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Design of three-dimensional domain-swapped dimers and fibrous oligomers. Proc.Natl.Acad.Sci.USA, 98, 2001
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4ONK
| [Leu-5]-Enkephalin mutant - YVVFL | Descriptor: | [Leu-5]-Enkephalin mutant - YVVFL | Authors: | Sangwan, S, Eisenberg, D, Sawaya, M.R, Do, T.D, Bowers, M.T, Lapointe, N.E, Teplow, D.B, Feinstein, S.C. | Deposit date: | 2014-01-28 | Release date: | 2014-07-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Factors that drive Peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants. J.Phys.Chem.B, 118, 2014
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4OLR
| [Leu-5]-Enkephalin mutant - YVVFV | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, [Leu-5]-Enkephalin mutant - YVVFV | Authors: | Sangwan, S, Eisenberg, D, Sawaya, M.R, Do, T.D, Bowers, M.T, Lapointe, N.E, Teplow, D.B, Feinstein, S.C. | Deposit date: | 2014-01-24 | Release date: | 2014-07-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Factors that drive Peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants. J.Phys.Chem.B, 118, 2014
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3LOW
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1YJO
| Structure of NNQQNY from yeast prion Sup35 with zinc acetate | Descriptor: | ACETIC ACID, Eukaryotic peptide chain release factor GTP-binding subunit, ZINC ION | Authors: | Nelson, R, Sawaya, M.R, Balbirnie, M, Madsen, A.O, Riekel, C, Grothe, R, Eisenberg, D. | Deposit date: | 2005-01-15 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure of the cross-beta spine of amyloid-like fibrils. Nature, 435, 2005
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1YJP
| Structure of GNNQQNY from yeast prion Sup35 | Descriptor: | Eukaryotic peptide chain release factor GTP-binding subunit | Authors: | Nelson, R, Sawaya, M.R, Balbirnie, M, Madsen, A.O, Riekel, C, Grothe, R, Eisenberg, D. | Deposit date: | 2005-01-15 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the cross-beta spine of amyloid-like fibrils. Nature, 435, 2005
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1YKW
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3G7W
| Islet Amyloid Polypeptide (IAPP or Amylin) Residues 1 to 22 fused to Maltose Binding Protein | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein, Islet amyloid polypeptide fusion protein, ... | Authors: | Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D. | Deposit date: | 2009-02-11 | Release date: | 2009-06-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process Protein Sci., 18, 2009
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1Z6K
| Citrate lyase beta subunit complexed with oxaloacetate and magnesium from M. tuberculosis | Descriptor: | Citrate Lyase beta subunit, MAGNESIUM ION, OXALOACETATE ION | Authors: | Goulding, C.W, Bowers, P.M, Segelke, B, Lekin, T, Kim, C.Y, Terwilliger, T.C, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2005-03-22 | Release date: | 2005-05-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function. J.Mol.Biol., 365, 2007
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