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PDB: 358 件

1F0V
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Crystal structure of an Rnase A dimer displaying a new type of 3D domain swapping
分子名称: 5'-D(*CP*G)-3', GLYCEROL, PHOSPHATE ION, ...
著者Liu, Y.S, Gotte, G, Libonati, M, Eisenberg, D.S.
登録日2000-05-17
公開日2001-02-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A domain-swapped RNase A dimer with implications for amyloid formation
Nat.Struct.Biol., 8, 2001
2A88
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Crystal structure of A Pantothenate synthetase, apo enzyme in C2 space group
分子名称: GLYCEROL, Pantoate--beta-alanine ligase, SULFATE ION
著者Wang, S, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2005-07-07
公開日2006-02-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of the Pantothenate Synthetase from Mycobacterium tuberculosis, Snapshots of the Enzyme in Action.
Biochemistry, 45, 2006
1AL1
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CRYSTAL STRUCTURE OF ALPHA1: IMPLICATIONS FOR PROTEIN DESIGN
分子名称: ALPHA HELIX PEPTIDE: ELLKKLLEELKG, SULFATE ION
著者Hill, C.P, Anderson, D.H, Wesson, L, Degrado, W.F, Eisenberg, D.
登録日1990-07-02
公開日1991-10-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of alpha 1: implications for protein design.
Science, 249, 1990
1DFN
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BU of 1dfn by Molmil
CRYSTAL STRUCTURE OF DEFENSIN HNP-3, AN AMPHIPHILIC DIMER: MECHANISMS OF MEMBRANE PERMEABILIZATION
分子名称: DEFENSIN HNP-3
著者Hill, C.P, Yee, J, Selsted, M.E, Eisenberg, D.
登録日1991-01-18
公開日1992-07-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization.
Science, 251, 1991
3PPD
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GGVLVN segment from Human Prostatic Acid Phosphatase Residues 260-265, involved in Semen-Derived Enhancer of Viral Infection
分子名称: ACETIC ACID, GGVLVN peptide, amyloid forming segment, ...
著者Zhao, A, Sawaya, M.R, Eisenberg, D.
登録日2010-11-24
公開日2011-06-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation.
Nature, 475, 2011
3NI3
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54-Membered ring macrocyclic beta-sheet peptide
分子名称: 54-membered ring macrocyclic beta-sheet peptide, ISOPROPYL ALCOHOL
著者Sawaya, M.R, Eisenberg, D, Nowick, J.S, Korman, T.P, Khakshoor, O.
登録日2010-06-15
公開日2010-09-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献X-ray crystallographic structure of an artificial beta-sheet dimer.
J.Am.Chem.Soc., 132, 2010
2OMM
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GNNQQNY peptide corresponding to residues 7-13 of yeast prion sup35
分子名称: GNNQQNY peptide corresponding to residues 7-13 of yeast prion sup35
著者Sawaya, M.R, Nelson, R, Eisenberg, D.
登録日2007-01-22
公開日2007-01-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Atomic structures of amyloid cross-beta spines reveal varied steric zippers.
Nature, 447, 2007
1S4Q
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Crystal Structure of Guanylate Kinase from Mycobacterium tuberculosis (Rv1389)
分子名称: CHLORIDE ION, FORMIC ACID, Guanylate kinase
著者Chan, S, Sawaya, M.R, Perry, L.J, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2004-01-16
公開日2004-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Crystal Structure of Guanylate Kinase from Mycobacterium tuberculosis
To be Published
2QYG
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Crystal Structure of a RuBisCO-like Protein rlp2 from Rhodopseudomonas palustris
分子名称: Ribulose bisphosphate carboxylase-like protein 2
著者Li, H, Chan, S, Tabita, F.R, Eisenberg, D.
登録日2007-08-14
公開日2007-09-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Function, structure, and evolution of the RubisCO-like proteins and their RubisCO homologs.
Microbiol.Mol.Biol.Rev., 71, 2007
3T4G
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AIIGLMV segment from Alzheimer's Amyloid-Beta displayed on 54-membered macrocycle scaffold
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide (ORN)AIIGLMV(ORN)KF(HAO)(4BF)K
著者Zhao, M, Liu, C, Cheng, P.N, Eisenberg, D, Nowick, J.S.
登録日2011-07-26
公開日2012-10-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Amyloid beta-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity.
Nat Chem, 4, 2012
1JBM
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Heptameric crystal structure of Mth649, an Sm-like archaeal protein from Methanobacterium thermautotrophicum
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, PUTATIVE SNRNP SM-LIKE PROTEIN
著者Mura, C, Eisenberg, D.
登録日2001-06-06
公開日2003-03-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)
Protein Sci., 12, 2003
4R0P
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Ifqins, an amyloid forming segment from human lysozyme spanning residues 56-61
分子名称: Lysozyme C
著者Sievers, S, Eisenberg, D.S, Sawaya, M.R.
登録日2014-08-01
公開日2014-12-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Structure-based design of functional amyloid materials.
J.Am.Chem.Soc., 136, 2014
1YJP
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Structure of GNNQQNY from yeast prion Sup35
分子名称: Eukaryotic peptide chain release factor GTP-binding subunit
著者Nelson, R, Sawaya, M.R, Balbirnie, M, Madsen, A.O, Riekel, C, Grothe, R, Eisenberg, D.
登録日2005-01-15
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the cross-beta spine of amyloid-like fibrils.
Nature, 435, 2005
3Q9G
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VQIVY segment from Alzheimer's tau displayed on 42-membered macrocycle scaffold
分子名称: ACETIC ACID, Cyclic pseudo-peptide VQIV(4BF)(ORN)(HAO)KL(ORN), GLYCEROL
著者Liu, C, Sawaya, M.R, Eisenberg, D, Nowick, J.S, Cheng, P, Zheng, J.
登録日2011-01-07
公開日2011-06-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics.
J.Am.Chem.Soc., 133, 2011
3NVF
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IIHFGS segment 138-143 from human prion
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2010-07-08
公開日2011-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3NVG
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MIHFGN segment 137-142 from mouse prion
分子名称: Major prion protein
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2010-07-08
公開日2011-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
1LU4
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BU of 1lu4 by Molmil
1.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A SECRETED MYCOBACTERIUM TUBERCULOSIS DISULFIDE OXIDOREDUCTASE HOMOLOGOUS TO E. COLI DSBE: IMPLICATIONS FOR FUNCTIONS
分子名称: SOLUBLE SECRETED ANTIGEN MPT53
著者Goulding, C.W, Apostol, M.I, Gleiter, S, Parseghian, A, Bardwell, J, Gennaro, M, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2002-05-21
公開日2003-10-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Gram-positive DsbE Proteins Function Differently from Gram-negative DsbE Homologs: A STRUCTURE TO FUNCTION ANALYSIS OF DsbE FROM MYCOBACTERIUM TUBERCULOSIS.
J.Biol.Chem., 279, 2004
1F1G
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Crystal structure of yeast cuznsod exposed to nitric oxide
分子名称: COPPER (II) ION, COPPER-ZINC SUPEROXIDE DISMUTASE, PHOSPHATE ION, ...
著者Hart, P.J, Ogihara, N.L, Liu, H, Nersissian, A.M, Valentine, J.S, Eisenberg, D.
登録日2000-05-18
公開日2002-12-12
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A structure-based mechanism for copper-zinc superoxide dismutase.
Biochemistry, 38, 1999
1HTQ
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BU of 1htq by Molmil
Multicopy crystallographic structure of a relaxed glutamine synthetase from Mycobacterium tuberculosis
分子名称: ADENOSINE MONOPHOSPHATE, CITRIC ACID, MANGANESE (II) ION, ...
著者Gill, H.S, Pfluegl, G.M, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2001-01-01
公開日2002-07-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Multicopy crystallographic refinement of a relaxed glutamine synthetase from Mycobacterium tuberculosis highlights flexible loops in the enzymatic mechanism and its regulation.
Biochemistry, 41, 2002
3NVH
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MIHFGND segment 137-143 from mouse prion
分子名称: Major prion protein, trifluoroacetic acid
著者Apostol, M.I, Sawaya, M.R, Eisenberg, D.
登録日2010-07-08
公開日2011-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3OVL
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BU of 3ovl by Molmil
Structure of an amyloid forming peptide VQIVYK from the TAU protein in complex with orange G
分子名称: 7-hydroxy-8-[(E)-phenyldiazenyl]naphthalene-1,3-disulfonic acid, ACETIC ACID, Microtubule-associated protein, ...
著者Landau, M, Eisenberg, D.
登録日2010-09-16
公開日2011-07-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Towards a pharmacophore for amyloid.
Plos Biol., 9, 2011
1JRI
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The Crystal Structure of an Sm-like Archaeal Protein with Two Heptamers in the Asymmetric Unit.
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Sm-like Archaeal Protein 1 (SmAP1)
著者Mura, C, Eisenberg, D.
登録日2001-08-13
公開日2002-02-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)
Protein Sci., 12, 2003
1EWF
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THE 1.7 ANGSTROM CRYSTAL STRUCTURE OF BPI
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN
著者Kleiger, G, Beamer, L.J, Grothe, R, Mallick, P, Eisenberg, D.
登録日2000-04-25
公開日2000-06-21
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The 1.7 A crystal structure of BPI: a study of how two dissimilar amino acid sequences can adopt the same fold.
J.Mol.Biol., 299, 2000
1G6U
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CRYSTAL STRUCTURE OF A DOMAIN SWAPPED DIMER
分子名称: DOMAIN SWAPPED DIMER, SULFATE ION, trifluoroacetic acid
著者Ogihara, N.L, Ghirlanda, G, Bryson, J.W, Gingery, M, DeGrado, W.F, Eisenberg, D.
登録日2000-11-07
公開日2001-02-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Design of three-dimensional domain-swapped dimers and fibrous oligomers.
Proc.Natl.Acad.Sci.USA, 98, 2001
1JS0
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Crystal Structure of 3D Domain-swapped RNase A Minor Trimer
分子名称: RIBONUCLEASE A, SULFATE ION
著者Liu, Y, Gotte, G, Libonati, M, Eisenberg, D.
登録日2001-08-15
公開日2002-03-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of the two 3D domain-swapped RNase A trimers.
Protein Sci., 11, 2002

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