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PDB: 198 件

8RQ3
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Cryo-em structure of the rat Multidrug resistance-associated protein 2 (rMrp2) in an autoinhibited state (nucleotide-free)
分子名称: ATP-binding cassette sub-family C member 2
著者Mazza, T, Beis, K.
登録日2024-01-17
公開日2024-02-14
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.
Nat Commun, 15, 2024
8RZX
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BU of 8rzx by Molmil
Solution structure of a parallel stranded G-quadruplex formed in ORAI1 promoter
分子名称: DNA (5'-D(*TP*GP*GP*GP*CP*GP*GP*GP*GP*CP*AP*CP*AP*GP*GP*TP*GP*GP*GP*CP*GP*GP*GP*G)-3')
著者Jana, J, Weisz, K.
登録日2024-02-13
公開日2024-08-21
最終更新日2024-09-11
実験手法SOLUTION NMR
主引用文献Remodeling Ca 2+ dynamics by targeting a promising E-box containing G-quadruplex at ORAI1 promoter in triple-negative breast cancer.
Cell Calcium, 123, 2024
4RSG
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BU of 4rsg by Molmil
Neutron crystal structure of Ras bound to the GTP analogue GppNHp
分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Knihtila, R.R, Holzapfel, G, Weiss, K.L, Meilleur, F, Mattos, C.
登録日2014-11-07
公開日2015-11-04
最終更新日2024-02-28
実験手法NEUTRON DIFFRACTION (1.907 Å)
主引用文献Neutron Crystal Structure of RAS GTPase Puts in Question the Protonation State of the GTP gamma-Phosphate.
J.Biol.Chem., 290, 2015
8R6D
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BU of 8r6d by Molmil
A quadruplex-duplex hybrid with a three-layered hybrid-2 G-quadruplex topology
分子名称: DNA (31-MER)
著者Vianney, Y.M, Weisz, K.
登録日2023-11-22
公開日2024-03-06
最終更新日2024-07-10
実験手法SOLUTION NMR
主引用文献Structural Differences at Quadruplex-Duplex Interfaces Enable Ligand-Induced Topological Transitions.
Adv Sci, 11, 2024
8R6G
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A quadruplex-duplex hybrid with a three-layered chair G-quadruplex topology
分子名称: DNA (33-MER)
著者Vianney, Y.M, Weisz, K.
登録日2023-11-22
公開日2024-03-13
最終更新日2024-07-10
実験手法SOLUTION NMR
主引用文献Structural Differences at Quadruplex-Duplex Interfaces Enable Ligand-Induced Topological Transitions.
Adv Sci, 11, 2024
6DZ1
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BU of 6dz1 by Molmil
Studies of Ion Transport in K+ Channels
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein
著者Langan, P.S, Vandavasi, V.G, Weiss, K.L, Wagner, A, Duman, R, El Omari, K, Afonine, P.V, Coates, L.
登録日2018-07-02
公開日2018-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Anomalous X-ray diffraction studies of ion transport in K+channels.
Nat Commun, 9, 2018
8R6H
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BU of 8r6h by Molmil
A quadruplex-duplex hybrid with a three-layered hybrid-2 G-quadruplex topology complexed with Phen-DC3
分子名称: DNA (34-MER), N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide
著者Vianney, Y.M, Weisz, K.
登録日2023-11-22
公開日2024-03-06
最終更新日2024-07-10
実験手法SOLUTION NMR
主引用文献Structural Differences at Quadruplex-Duplex Interfaces Enable Ligand-Induced Topological Transitions.
Adv Sci, 11, 2024
6CSN
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BU of 6csn by Molmil
Crystal structure of the designed light-gated anion channel iC++ at pH8.5
分子名称: CHLORIDE ION, OLEIC ACID, RETINAL, ...
著者Kato, H.E, Kim, Y, Yamashita, K, Kobilka, B.K, Deisseroth, K.
登録日2018-03-21
公開日2018-09-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural mechanisms of selectivity and gating in anion channelrhodopsins.
Nature, 561, 2018
6CSO
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BU of 6cso by Molmil
Crystal structure of the designed light-gated anion channel iC++ at pH6.5
分子名称: OLEIC ACID, RETINAL, iC++
著者Kato, H.E, Kim, Y, Yamashita, K, Kobilka, B.K, Deisseroth, K.
登録日2018-03-21
公開日2018-09-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural mechanisms of selectivity and gating in anion channelrhodopsins.
Nature, 561, 2018
8PSI
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BU of 8psi by Molmil
G-quadruplex with a 1-nt V-shaped loop from a G-rich sequence with five G-runs
分子名称: DNA (5'-D(*GP*GP*GP*TP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3')
著者Vianney, Y.M, Schroeder, N, Jana, J, Weisz, K.
登録日2023-07-13
公開日2023-09-27
最終更新日2023-10-18
実験手法SOLUTION NMR
主引用文献Showcasing Different G-Quadruplex Folds of a G-Rich Sequence: Between Rule-Based Prediction and Butterfly Effect.
J.Am.Chem.Soc., 145, 2023
8PSC
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BU of 8psc by Molmil
Three-layered basket-type G-quadruplex from a G-rich sequence with five G-runs
分子名称: DNA (5'-D(*AP*GP*(BG)P*GP*TP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*GP*CP*AP*GP*GP*GP*T)-3')
著者Vianney, Y.M, Schroeder, N, Jana, J, Weisz, K.
登録日2023-07-13
公開日2023-09-27
最終更新日2023-10-18
実験手法SOLUTION NMR
主引用文献Showcasing Different G-Quadruplex Folds of a G-Rich Sequence: Between Rule-Based Prediction and Butterfly Effect.
J.Am.Chem.Soc., 145, 2023
8PSB
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BU of 8psb by Molmil
Three-layered parallel G-quadruplex with snapback loop from a G-rich sequence with five G-runs
分子名称: DNA (5'-D(*AP*GP*GP*GP*TP*AP*GP*GP*GP*CP*GP*GP*CP*GP*GP*GP*GP*AP*CP*GP*GP*GP*T)-3')
著者Vianney, Y.M, Schroeder, N, Jana, J, Chojetzki, G, Weisz, K.
登録日2023-07-13
公開日2023-09-27
最終更新日2023-10-25
実験手法SOLUTION NMR
主引用文献Showcasing Different G-Quadruplex Folds of a G-Rich Sequence: Between Rule-Based Prediction and Butterfly Effect.
J.Am.Chem.Soc., 145, 2023
8R4E
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BU of 8r4e by Molmil
Hybrid-1R G-quadruplex with a +(lpp) loop progression
分子名称: DNA (27-MER)
著者Jana, J, Vianney, Y.M, Weisz, K.
登録日2023-11-13
公開日2023-12-27
最終更新日2024-01-31
実験手法SOLUTION NMR
主引用文献Impact of loop length and duplex extensions on the design of hybrid-type G-quadruplexes.
Chem.Commun.(Camb.), 60, 2024
5KSC
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BU of 5ksc by Molmil
E166A/R274N/R276N Toho-1 Beta-lactamase aztreonam acyl-enzyme intermediate
分子名称: 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid, Beta-lactamase Toho-1
著者Vandavasi, V.G, Langan, P.S, Weiss, K, Parks, J.M, Cooper, J.B, Ginell, S.L, Coates, L.
登録日2016-07-08
公開日2016-11-09
最終更新日2024-10-09
実験手法NEUTRON DIFFRACTION (2.1 Å)
主引用文献Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A beta-Lactamase with a Monobactam Substrate.
Antimicrob. Agents Chemother., 61, 2017
7O1H
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BU of 7o1h by Molmil
Hybrid-2R quadruplex-duplex with (-p-p-l) topology and 3 syn residues
分子名称: DNA (31-MER)
著者Mohr, S, Vianney, Y.M, Weisz, K.
登録日2021-03-29
公開日2021-05-19
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Expanding the Topological Landscape by a G-Column Flip of a Parallel G-Quadruplex.
Chemistry, 27, 2021
6CSM
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BU of 6csm by Molmil
Crystal structure of the natural light-gated anion channel GtACR1
分子名称: GtACR1, OLEIC ACID, RETINAL
著者Kato, H.E, Kim, Y, Yamashita, K, Kobilka, B.K, Deisseroth, K.
登録日2018-03-21
公開日2018-09-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural mechanisms of selectivity and gating in anion channelrhodopsins.
Nature, 561, 2018
8QVS
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BU of 8qvs by Molmil
Crystal structure of Ompk36 GD at 3500 eV based on a combination of spherical harmonics and analytical absorption corrections
分子名称: OmpK36, SULFATE ION
著者Duman, R, Wagner, A, Beis, K, Wong, J.
登録日2023-10-18
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Ray-tracing analytical absorption correction for X-ray crystallography based on tomographic reconstructions.
J.Appl.Crystallogr., 57, 2024
8QVV
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BU of 8qvv by Molmil
Crystal structure of Ompk36 GD at 3500 eV based on analytical absorption corrections
分子名称: OmpK36, SULFATE ION
著者Duman, R, Wagner, A, Beis, K, Wong, J.
登録日2023-10-18
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Ray-tracing analytical absorption correction for X-ray crystallography based on tomographic reconstructions.
J.Appl.Crystallogr., 57, 2024
8QUR
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BU of 8qur by Molmil
Crystal structure of Ompk36 GD at 3500 eV with no absorption corrections
分子名称: OmpK36, SULFATE ION
著者Duman, R, Wagner, A, Beis, K, Wong, J.
登録日2023-10-16
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Ray-tracing analytical absorption correction for X-ray crystallography based on tomographic reconstructions.
J.Appl.Crystallogr., 57, 2024
8QUQ
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BU of 8quq by Molmil
Crystal structure of Ompk36 GD at 3500 eV based on spherical harmonics absorption corrections
分子名称: OmpK36, SULFATE ION
著者Duman, R, Wagner, A, Beis, K, Wong, J.
登録日2023-10-16
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Ray-tracing analytical absorption correction for X-ray crystallography based on tomographic reconstructions.
J.Appl.Crystallogr., 57, 2024
7P34
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BU of 7p34 by Molmil
Cryo-EM structure of the proton-dependent antibacterial peptide transporter SbmA-FabS11-1 in nanodiscs
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Peptide antibiotic transporter SbmA
著者Ghilarov, D, Beis, K.
登録日2021-07-07
公開日2021-09-15
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Molecular mechanism of SbmA, a promiscuous transporter exploited by antimicrobial peptides.
Sci Adv, 7, 2021
6R9K
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BU of 6r9k by Molmil
A quadruplex hybrid structure with lpp loop orientation and 3 syn residues
分子名称: DNA (25-MER)
著者Karg, B, Weisz, K.
登録日2019-04-03
公開日2019-07-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Duplex-Guided Refolding into Novel G-Quadruplex (3+1) Hybrid Conformations.
Angew.Chem.Int.Ed.Engl., 58, 2019
6R9L
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BU of 6r9l by Molmil
A quadruplex hybrid structure with lpp loop orientation and 5 syn residues
分子名称: DNA (25-MER)
著者Karg, B, Weisz, K.
登録日2019-04-03
公開日2019-07-03
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Duplex-Guided Refolding into Novel G-Quadruplex (3+1) Hybrid Conformations.
Angew.Chem.Int.Ed.Engl., 58, 2019
5OV2
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BU of 5ov2 by Molmil
2'F-ANA-G modified quadruplex with a flipped tetrad
分子名称: artificial quadruplex with propeller, diagonal, and lateral loop
著者Dickerhoff, J, Weisz, K.
登録日2017-08-27
公開日2017-10-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Nonconventional C-HF Hydrogen Bonds Support a Tetrad Flip in Modified G-Quadruplexes.
J Phys Chem Lett, 8, 2017
8RW2
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BU of 8rw2 by Molmil
Structure of a chair-type antiparallel quadruplex-duplex hybrid at pH 6
分子名称: DNA (33-MER)
著者Vianney, Y.M, Weisz, K.
登録日2024-02-02
公開日2024-03-27
最終更新日2024-06-05
実験手法SOLUTION NMR
主引用文献A pH-Responsive Topological Switch Based on a DNA Quadruplex-Duplex Hybrid.
Chemistry, 30, 2024

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