4RSG
Neutron crystal structure of Ras bound to the GTP analogue GppNHp
Summary for 4RSG
| Entry DOI | 10.2210/pdb4rsg/pdb |
| Descriptor | GTPase HRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (4 entities in total) |
| Functional Keywords | oncoprotein, nucleotide-binding protein, protein-nucleotide complex, signaling protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell membrane. Isoform 2: Nucleus: P01112 |
| Total number of polymer chains | 1 |
| Total formula weight | 19421.69 |
| Authors | Knihtila, R.R.,Holzapfel, G.,Weiss, K.L.,Meilleur, F.,Mattos, C. (deposition date: 2014-11-07, release date: 2015-11-04, Last modification date: 2024-02-28) |
| Primary citation | Knihtila, R.,Holzapfel, G.,Weiss, K.,Meilleur, F.,Mattos, C. Neutron Crystal Structure of RAS GTPase Puts in Question the Protonation State of the GTP gamma-Phosphate. J.Biol.Chem., 290:31025-31036, 2015 Cited by PubMed: 26515069DOI: 10.1074/jbc.M115.679860 PDB entries with the same primary citation |
| Experimental method | NEUTRON DIFFRACTION (1.907 Å) |
Structure validation
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