1Y8V
 
 | | Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-propyl Thymidine (T*) | | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*(P2T)P*AP*CP*GP*C)-3' | | 著者 | Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M. | | 登録日 | 2004-12-13 | | 公開日 | 2005-06-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
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1Y9S
 | | Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-propargyl Thymidine (T*) | | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*(2GT)P*AP*CP*GP*C)-3') | | 著者 | Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M. | | 登録日 | 2004-12-16 | | 公開日 | 2005-06-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
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1YBC
 | | Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(benzyloxy)ethyl] Thymidine (T*) | | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*(BOE)P*AP*CP*GP*C)-3'), STRONTIUM ION | | 著者 | Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M. | | 登録日 | 2004-12-20 | | 公開日 | 2005-06-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
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1Y7F
 | | Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-[hydroxy(methyleneamino)oxy]ethyl] Thymidine (T*) | | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*(2NT)P*AP*CP*GP*C)-3'), BARIUM ION | | 著者 | Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M. | | 登録日 | 2004-12-08 | | 公開日 | 2005-06-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
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1YB9
 | | Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(N,N-dimethylaminooxy)ethyl] Thymidine (T*) | | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*(2OT)P*AP*CP*GP*C)-3'), SPERMINE | | 著者 | Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M. | | 登録日 | 2004-12-20 | | 公開日 | 2005-06-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
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1D17
 | | DNA-NOGALAMYCIN INTERACTIONS | | 分子名称: | DNA (5'-D(*(5CM)P*GP*TP*AP*(5CM)P*G)-3'), NOGALAMYCIN | | 著者 | Egli, M, Williams, L.D, Frederick, C.A, Rich, A. | | 登録日 | 1990-08-08 | | 公開日 | 1991-07-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | DNA-nogalamycin interactions.
Biochemistry, 30, 1991
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4DUG
 | | Crystal Structure of Circadian Clock Protein KaiC E318A Mutant | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase kaiC, MAGNESIUM ION, ... | | 著者 | Egli, M, Mori, T, Pattanayek, R, Xu, Y, Qin, X, Johnson, C.H. | | 登録日 | 2012-02-21 | | 公開日 | 2012-03-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.292 Å) | | 主引用文献 | Dephosphorylation of the Core Clock Protein KaiC in the Cyanobacterial KaiABC Circadian Oscillator Proceeds via an ATP Synthase Mechanism.
Biochemistry, 51, 2012
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3SD8
 | | Crystal structure of Ara-FHNA decamer DNA | | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*(F4H)P*AP*CP*GP*C)-3', STRONTIUM ION | | 著者 | Egli, M, Pallan, P.S. | | 登録日 | 2011-06-08 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Structural Origins of Opposite Effects on Stability by Axial and Equatorial 3'-Fluoro Modifications of Hexitol Nucleic Acid (HNA)
To be Published
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4DKZ
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1I5W
 | | A-DNA DECAMER GCGTA(TLN)ACGC | | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*(TLN)P*AP*CP*GP*C)-3' | | 著者 | Egli, M, Minasov, G, Teplova, M, Kumar, R, Wengel, J. | | 登録日 | 2001-03-01 | | 公開日 | 2001-04-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | X-ray crystal structure of a locked nucleic acid (LNA) duplex composed of a palindromic 10-mer DNA strand containing one LNA thymine monomer
J.Chem.Soc.,Chem.Commun., 2001
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1D48
 | | STRUCTURE OF THE PURE-SPERMINE FORM OF Z-DNA (MAGNESIUM FREE) AT 1 ANGSTROM RESOLUTION | | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), SPERMINE | | 著者 | Egli, M, Williams, L.D, Gao, Q, Rich, A. | | 登録日 | 1991-09-11 | | 公開日 | 1992-04-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Structure of the pure-spermine form of Z-DNA (magnesium free) at 1-A resolution.
Biochemistry, 30, 1991
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1L3D
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1L2X
 | | Atomic Resolution Crystal Structure of a Viral RNA Pseudoknot | | 分子名称: | MAGNESIUM ION, POTASSIUM ION, RNA pseudoknot, ... | | 著者 | Egli, M, Minasov, G, Su, L, Rich, A. | | 登録日 | 2002-02-25 | | 公開日 | 2002-03-22 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Metal ions and flexibility in a viral RNA pseudoknot at atomic resolution.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1MLX
 | | Crystal Structure Analysis of a 2'-O-[2-(Methylthio)-ethyl]-Modified Oligodeoxynucleotide Duplex | | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*SMTP*AP*CP*GP*C)-3' | | 著者 | Prakash, T.P, Manoharan, M, Kawasaki, A.M, Fraser, A.S, Lesnik, E.A, Sioufi, N, Leeds, J.M, Teplova, M, Egli, M. | | 登録日 | 2002-08-31 | | 公開日 | 2002-12-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | 2'-O-[2-(Methylthio)ethyl]-Modified Oligonucleotide: An Analogue of 2'-O-[2-(Methoxy)-ethyl]-Modified
Oligonucleotide with Improved Protein Binding Properties and High Binding Affinity to Target RNA
Biochemistry, 41, 2002
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1EH4
 | | BINARY COMPLEX OF CASEIN KINASE-1 FROM S. POMBE WITH AN ATP COMPETITIVE INHIBITOR, IC261 | | 分子名称: | 3-[(2,4,6-TRIMETHOXY-PHENYL)-METHYLENE]-INDOLIN-2-ONE, CASEIN KINASE-1, SULFATE ION | | 著者 | Mashhoon, N, Demaggio, A.J, Tereshko, V, Bergmeier, S.C, Egli, M, Hoekstra, M.F, Kuret, J. | | 登録日 | 2000-02-18 | | 公開日 | 2001-09-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of a Conformation-Selective Casein Kinase-1 Inhibitor
J.Biol.Chem., 275, 2000
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3CJZ
 | | Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m22G:A pairs | | 分子名称: | RNA (5'-R(*GP*GP*AP*CP*GP*(M2G)P*AP*CP*GP*UP*CP*CP*U)-3') | | 著者 | Pallan, P.S, Kreutz, C, Bosio, S, Micura, R, Egli, M. | | 登録日 | 2008-03-14 | | 公開日 | 2008-10-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs.
Rna, 14, 2008
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1EI4
 | | B-DNA DODECAMER CGCGAAT(TLC)CGCG WITH INCORPORATED [3.3.0]BICYCLO-ARABINO-THYMINE-5'-PHOSPHATE | | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TLC)P*(TLC)P*CP*GP*CP*G)-3'), MAGNESIUM ION, SPERMINE | | 著者 | Minasov, G, Teplova, M, Nielsen, P, Wengel, J, Egli, M. | | 登録日 | 2000-02-24 | | 公開日 | 2000-03-27 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Structural basis of cleavage by RNase H of hybrids of arabinonucleic acids and RNA.
Biochemistry, 39, 2000
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6XHC
 | | Structure of glycinyl 5'-O-adenosine phosphoramidate | | 分子名称: | 2-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]amino]ethanoic acid, Ribonuclease pancreatic | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2020-06-18 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid.
Angew.Chem.Int.Ed.Engl., 59, 2020
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1N1O
 | | Crystal Structure of a B-form DNA Duplex Containing (L)-alpha-threofuranosyl (3'-2') Nucleosides: A Four-Carbon Sugar is Easily Accommodated into the Backbone of DNA | | 分子名称: | 5'-D(*CP*GP*CP*GP*AP*AP*(TFT)P*TP*CP*GP*CP*G)-3', MAGNESIUM ION | | 著者 | Wilds, C.J, Wawrzak, Z, Krishnamurthy, R, Eschenmoser, A, Egli, M. | | 登録日 | 2002-10-18 | | 公開日 | 2002-11-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Crystal Structure of a B-Form DNA Duplex Containing (L)-alpha-Threofuranosyl (3'-->2') Nucleosides: A
Four-Carbon Sugar Is Easily Accommodated into the Backbone of DNA
J.Am.Chem.Soc., 124, 2002
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2R8I
 | | Selectivity of Nucleoside Triphosphate Incorporation Opposite 1,N2-Propanodeoxyguanosine (PdG) by the Sulfolobus solfataricus DNA Polymerase Dpo4 Polymerase | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*DGP*DGP*DGP*DGP*DGP*DAP*DAP*DGP*DGP*DAP*DTP*DTP*DC)-3'), ... | | 著者 | Wang, Y, Saleh, S, Marnette, L.J, Egli, M, Stone, M.P. | | 登録日 | 2007-09-10 | | 公開日 | 2008-07-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV
Biochemistry, 47, 2008
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2R8H
 | | Selectivity of Nucleoside Triphosphate Incorporation Opposite 1,N2-Propanodeoxyguanosine (PdG) by the Sulfolobus solfataricus DNA Polymerase Dpo4 Polymerase | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*DGP*DGP*DGP*DGP*DGP*DAP*DAP*DGP*DGP*DAP*DTP*DTP*DC)-3'), ... | | 著者 | Wang, Y, Saleh, S, Marnette, L.J, Egli, M, Stone, M.P. | | 登録日 | 2007-09-10 | | 公開日 | 2008-07-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV
Biochemistry, 47, 2008
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2R8G
 | | Selectivity of Nucleoside Triphosphate Incorporation Opposite 1,N2-Propanodeoxyguanosine (PdG) by the Sulfolobus solfataricus DNA Polymerase Dpo4 Polymerase | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*DGP*DGP*DGP*DGP*DGP*DAP*DAP*DGP*DGP*DAP*DTP*DTP*DT)-3', 5'-D(*DTP*DCP*DAP*DCP*(P)P*DGP*DAP*DAP*DAP*DTP*DCP*DCP*DTP*DTP*DCP*DCP*DCP*DCP*DC)-3', ... | | 著者 | Wang, Y, Saleh, S, Marnette, L.J, Egli, M, Stone, M.P. | | 登録日 | 2007-09-10 | | 公開日 | 2008-07-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV
Biochemistry, 47, 2008
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2GBL
 | | Crystal Structure of Full Length Circadian Clock Protein KaiC with Phosphorylation Sites | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase kaiC, MAGNESIUM ION | | 著者 | Pattanayek, R, Williams, D.R, Pattanayek, S, Xu, Y, Mori, T, Johnson, C.H, Stewart, P.L, Egli, M. | | 登録日 | 2006-03-10 | | 公開日 | 2007-01-23 | | 最終更新日 | 2021-07-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Analysis of KaiA-KaiC protein interactions in the cyano-bacterial circadian clock using hybrid structural methods.
Embo J., 25, 2006
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5W1Z
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8FTJ
 | | Crystal structure of human NEIL1 (P2G (242K) C(delta)100) glycosylase bound to DNA duplex containing urea | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*TP*CP*CP*AP*UDV*GP*TP*CP*TP*AP*CP)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*AP*TP*GP*GP*AP*CP*GP*G)-3'), ... | | 著者 | Tomar, R, Sharma, P, Harp, J.M, Egli, M, Stone, M.P. | | 登録日 | 2023-01-12 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Base excision repair of the N-(2-deoxy-d-erythro-pentofuranosyl)-urea lesion by the hNEIL1 glycosylase.
Nucleic Acids Res., 51, 2023
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