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3SD8

Crystal structure of Ara-FHNA decamer DNA

Summary for 3SD8
Entry DOI10.2210/pdb3sd8/pdb
Descriptor5'-D(*GP*CP*GP*TP*AP*(F4H)P*AP*CP*GP*C)-3', STRONTIUM ION (3 entities in total)
Functional Keywordsa-form dna, ara-3'-fluoro hexitol nucleic acid, ara-fhna, antisense oligonucleotides, dna
Total number of polymer chains2
Total formula weight6241.67
Authors
Egli, M.,Pallan, P.S. (deposition date: 2011-06-08, release date: 2012-08-29, Last modification date: 2023-09-13)
Primary citationEgli, M.,Pallan, P.S.,Allerson, C.R.,Prakash, T.P.,Berdeja, A.,Yu, J.,Bhat, B.,Swayze, E.E.,Seth, P.
Structural Origins of Opposite Effects on Stability by Axial and Equatorial 3'-Fluoro Modifications of Hexitol Nucleic Acid (HNA)
To be Published,
Experimental method
X-RAY DIFFRACTION (1.67 Å)
Structure validation

218853

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