4UWA
 
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4UWE
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3POU
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3M9S
 | | Crystal structure of respiratory complex I from Thermus thermophilus | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | | Authors: | Efremov, R.G, Baradaran, R, Sazanov, L.A. | | Deposit date: | 2010-03-22 | | Release date: | 2010-05-26 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | The architecture of respiratory complex I
Nature, 465, 2010
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3M9C
 | | Crystal structure of the membrane domain of respiratory complex I from Escherichia coli | | Descriptor: | NADH-quinone oxidoreductase subunit NuoL, NADH-quinone oxidoreductase subunit NuoM, NADH-quinone oxidoreductase subunit NuoN, ... | | Authors: | Efremov, R.G, Baradaran, R, Sazanov, L.A. | | Deposit date: | 2010-03-22 | | Release date: | 2010-05-26 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.9 Å) | | Cite: | The architecture of respiratory complex I
Nature, 465, 2010
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3POQ
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3POX
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3RKO
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1IH9
 | | NMR Structure of Zervamicin IIB (peptaibol antibiotic) Bound to DPC Micelles | | Descriptor: | ZERVAMICIN IIB | | Authors: | Shenkarev, Z.O, Balasheva, T.A, Efremov, R.G, Yakimenko, Z.A, Ovchinnikova, T.V, Raap, J, Arseniev, A.S. | | Deposit date: | 2001-04-19 | | Release date: | 2002-02-13 | | Last modified: | 2012-12-12 | | Method: | SOLUTION NMR | | Cite: | Spatial Structure of Zervamicin Iib Bound to Dpc Micelles: Implications for Voltage-Gating.
Biophys.J., 82, 2002
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5LUE
 | | Minor form of the recombinant cytotoxin-1 from N. oxiana | | Descriptor: | VC-1=CYTOTOXIN | | Authors: | Dubovskii, P.V, Dubinnyi, M.A, Shulepko, M.A, Lyukmanova, E.N, Dolgikh, D.A, Kirpichnikov, M.P, Efremov, R.G. | | Deposit date: | 2016-09-08 | | Release date: | 2017-09-20 | | Last modified: | 2019-05-08 | | Method: | SOLUTION NMR | | Cite: | Structural and Dynamic "Portraits" of Recombinant and Native Cytotoxin I from Naja oxiana: How Close Are They?
Biochemistry, 56, 2017
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2F93
 | | K Intermediate Structure of Sensory Rhodopsin II/Transducer Complex in Combination with the Ground State Structure | | Descriptor: | RETINAL, Sensory rhodopsin II, Sensory rhodopsin II transducer, ... | | Authors: | Moukhametzianov, R.I, Klare, J.P, Efremov, R.G, Baecken, C, Goeppner, A, Labahn, J, Engelhard, M, Bueldt, G, Gordeliy, V.I. | | Deposit date: | 2005-12-05 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Development of the signal in sensory rhodopsin and its transfer to the cognate transducer.
Nature, 440, 2006
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2F95
 | | M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure | | Descriptor: | RETINAL, Sensory rhodopsin II, Sensory rhodopsin II transducer, ... | | Authors: | Moukhametzianov, R.I, Klare, J.P, Efremov, R.G, Baecken, C, Goeppner, A, Labahn, J, Engelhard, M, Bueldt, G, Gordeliy, V.I. | | Deposit date: | 2005-12-05 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Development of the signal in sensory rhodopsin and its transfer to the cognate transducer.
Nature, 440, 2006
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8OQY
 | | Structure of apo form of human gamma-secretase PSEN1 APH-1B isoform reconstituted into lipid nanodisc | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Odorcic, I, Chavez Gutierrez, L, Efremov, R.G. | | Deposit date: | 2023-04-12 | | Release date: | 2024-04-24 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Apo and A beta 46-bound gamma-secretase structures provide insights into amyloid-beta processing by the APH-1B isoform.
Nat Commun, 15, 2024
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8OQZ
 | | Structure of human gamma-secretase PSEN1 APH-1B isoform reconstituted into lipid nanodisc in complex with Ab46 | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Odorcic, I, Chavez Gutierrez, L, Efremov, R.G. | | Deposit date: | 2023-04-12 | | Release date: | 2024-04-24 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Apo and A beta 46-bound gamma-secretase structures provide insights into amyloid-beta processing by the APH-1B isoform.
Nat Commun, 15, 2024
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1H2S
 | | Molecular basis of transmenbrane signalling by sensory rhodopsin II-transducer complex | | Descriptor: | RETINAL, SENSORY RHODOPSIN II, SENSORY RHODOPSIN II TRANSDUCER, ... | | Authors: | Gordeliy, V.I, Labahn, J, Moukhametzianov, R, Efremov, R, Granzin, J, Schlesinger, R, Bueldt, G, Savopol, T, Scheidig, A, Klare, J.P, Engelhard, M. | | Deposit date: | 2002-08-15 | | Release date: | 2002-10-10 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Molecular Basis of Transmembrane Signalling by Sensory Rhodopsin II-Transducer Complex
Nature, 419, 2002
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5T8A
 | | Recombinant cytotoxin-I from the venom of cobra N. oxiana | | Descriptor: | Cytotoxin 1 | | Authors: | Dubovskii, P.V, Dubinnyi, M.A, Shulepko, M.A, Lyukmanova, E.N, Dolgikh, D.A, Kirpichnikov, M.P, Efremov, R.G. | | Deposit date: | 2016-09-07 | | Release date: | 2017-09-20 | | Last modified: | 2019-05-08 | | Method: | SOLUTION NMR | | Cite: | Structural and Dynamic "Portraits" of Recombinant and Native Cytotoxin I from Naja oxiana: How Close Are They?
Biochemistry, 56, 2017
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1ZAD
 | | Structure of cytotoxin I (CTI) from Naja Oxiana in complex with DPC micelle | | Descriptor: | Cytotoxin 1 | | Authors: | Dubinnyi, M.A, Pustovalova, Y.E, Dubovskii, P.V, Utkin, Y.N, Konshina, A.G, Efremov, R.G, Arseniev, A.S. | | Deposit date: | 2005-04-06 | | Release date: | 2006-06-20 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Interaction of three-finger toxins with phospholipid membranes: comparison of S- and P-type cytotoxins
Biochem.J., 387, 2005
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4O9Y
 | | Crystal Structure of TcdA1 | | Descriptor: | TcdA1 | | Authors: | Meusch, D, Gatsogiannis, C, Efremov, R.G, Lang, A.E, Hofnagel, O, Vetter, I.R, Aktories, K, Raunser, S. | | Deposit date: | 2014-01-03 | | Release date: | 2014-02-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.502 Å) | | Cite: | Mechanism of Tc toxin action revealed in molecular detail.
Nature, 508, 2014
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4O9X
 | | Crystal Structure of TcdB2-TccC3 | | Descriptor: | MERCURY (II) ION, TcdB2, TccC3 | | Authors: | Meusch, D, Gatsogiannis, C, Efremov, R.G, Lang, A.E, Hofnagel, O, Vetter, I.R, Aktories, K, Raunser, S. | | Deposit date: | 2014-01-03 | | Release date: | 2014-02-26 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Mechanism of Tc toxin action revealed in molecular detail.
Nature, 508, 2014
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1DXZ
 | | M2 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 20 STRUCTURES | | Descriptor: | ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA CHAIN | | Authors: | Pashkov, V.S, Maslennikov, I.V, Tchikin, L.D, Efremov, R.G, Ivanov, V.T, Arseniev, A.S. | | Deposit date: | 2000-01-20 | | Release date: | 2000-02-02 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Spatial Structure of the M2 Transmembrane Segment of the Nicotinic Acetylcholine Receptor Alpha-Subunit
FEBS Lett., 457, 1999
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5NQ4
 | | Cytotoxin-1 in DPC-micelle | | Descriptor: | Cytotoxin 1 | | Authors: | Dubovskii, P.V, Dubinnyi, M.A, Volynsky, P.E, Pustovalova, Y.E, Konshina, A.G, Utkin, Y.N, Efremov, R.G, Arseniev, A.S. | | Deposit date: | 2017-04-19 | | Release date: | 2017-12-13 | | Last modified: | 2019-05-08 | | Method: | SOLUTION NMR | | Cite: | Impact of membrane partitioning on the spatial structure of an S-type cobra cytotoxin.
J. Biomol. Struct. Dyn., 36, 2018
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7QD8
 | | Cryo-EM structure of Tn4430 TnpA transposase from Tn3 family in apo state | | Descriptor: | Transposase for transposon Tn4430 | | Authors: | Shkumatov, A.V, Oger, C.A, Aryanpour, N, Hallet, B.F, Efremov, R.G. | | Deposit date: | 2021-11-26 | | Release date: | 2022-10-26 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural insight into Tn3 family transposition mechanism.
Nat Commun, 13, 2022
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7QD4
 | | Cryo-EM structure of Tn4430 TnpA transposase from Tn3 family in complex with 100 bp long transposon end DNA | | Descriptor: | IR100 DNA substrate, none transferred strand, transferred strand, ... | | Authors: | Shkumatov, A.V, Oger, C.A, Aryanpour, N, Hallet, B.F, Efremov, R.G. | | Deposit date: | 2021-11-26 | | Release date: | 2022-10-26 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural insight into Tn3 family transposition mechanism.
Nat Commun, 13, 2022
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7QD6
 | | Cryo-EM structure of Tn4430 TnpA transposase from Tn3 family in complex with strand-transfer like DNA product | | Descriptor: | IR71st non transferred strand, IR71st transferred strand, Transposase for transposon Tn4430 | | Authors: | Shkumatov, A.V, Oger, C.A, Aryanpour, N, Hallet, B.F, Efremov, R.G. | | Deposit date: | 2021-11-26 | | Release date: | 2022-10-26 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insight into Tn3 family transposition mechanism.
Nat Commun, 13, 2022
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7QD5
 | | Cryo-EM structure of Tn4430 TnpA transposase from Tn3 family in complex with 48 bp long transposon end DNA | | Descriptor: | IR48 DNA substrate, non transferred strand, IR48 transferred strand, ... | | Authors: | Shkumatov, A.V, Oger, C.A, Aryanpour, N, Hallet, B.F, Efremov, R.G. | | Deposit date: | 2021-11-26 | | Release date: | 2022-10-26 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insight into Tn3 family transposition mechanism.
Nat Commun, 13, 2022
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