Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 112 results

1BS7
DownloadVisualize
BU of 1bs7 by Molmil
PEPTIDE DEFORMYLASE AS NI2+ CONTAINING FORM
Descriptor: NICKEL (II) ION, PROTEIN (PEPTIDE DEFORMYLASE), SULFATE ION
Authors:Becker, A, Schlichting, I, Kabsch, W, Groche, D, Schultz, S, Wagner, A.F.V.
Deposit date:1998-09-01
Release date:1999-08-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of peptide deformylase and identification of the substrate binding site.
J.Biol.Chem., 273, 1998
1CM5
DownloadVisualize
BU of 1cm5 by Molmil
CRYSTAL STRUCTURE OF C418A,C419A MUTANT OF PFL FROM E.COLI
Descriptor: CARBONATE ION, PROTEIN (PYRUVATE FORMATE-LYASE), SODIUM ION
Authors:Becker, A, Fritz-Wolf, K, Kabsch, W, Knappe, J, Schultz, S, Wagner, A.F.V.
Deposit date:1999-05-14
Release date:1999-12-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and mechanism of the glycyl radical enzyme pyruvate formate-lyase.
Nat.Struct.Biol., 6, 1999
4TLW
DownloadVisualize
BU of 4tlw by Molmil
CARDS TOXIN, FULL-LENGTH
Descriptor: ADP-ribosylating toxin CARDS
Authors:Becker, A, GALALELDEEN, A, Taylor, A.B, Hart, P.J.
Deposit date:2014-05-30
Release date:2015-04-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of CARDS toxin, a unique ADP-ribosylating and vacuolating cytotoxin from Mycoplasma pneumoniae.
Proc.Natl.Acad.Sci.USA, 112, 2015
3PFL
DownloadVisualize
BU of 3pfl by Molmil
CRYSTAL STRUCTURE OF PFL FROM E.COLI IN COMPLEX WITH SUBSTRATE ANALOGUE OXAMATE
Descriptor: OXAMIC ACID, PROTEIN (FORMATE ACETYLTRANSFERASE 1)
Authors:Becker, A, Fritz-Wolf, K, Kabsch, W, Knappe, J, Schultz, S, Wagner, A.F.V.
Deposit date:1999-05-14
Release date:2000-05-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and mechanism of the glycyl radical enzyme pyruvate formate-lyase.
Nat.Struct.Biol., 6, 1999
2VWB
DownloadVisualize
BU of 2vwb by Molmil
Structure of the archaeal Kae1-Bud32 fusion protein MJ1130: a model for the eukaryotic EKC-KEOPS subcomplex involved in transcription and telomere homeostasis.
Descriptor: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE
Authors:Hecker, A, Lopreiato, R, Graille, M, Collinet, B, Forterre, P, Domenico, L, van Tilbeurgh, H.
Deposit date:2008-06-20
Release date:2008-08-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure of the Archaeal Kae1/Bud32 Fusion Protein Mj1130: A Model for the Eukaryotic Ekc/Keops Subcomplex
Embo J., 27, 2008
1BS5
DownloadVisualize
BU of 1bs5 by Molmil
PEPTIDE DEFORMYLASE AS ZN2+ CONTAINING FORM
Descriptor: PROTEIN (PEPTIDE DEFORMYLASE), SULFATE ION, ZINC ION
Authors:Becker, A, Schlichting, I, Kabsch, W, Groche, D, Schultz, S, Wagner, A.F.V.
Deposit date:1998-09-01
Release date:1999-08-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Iron center, substrate recognition and mechanism of peptide deformylase.
Nat.Struct.Biol., 5, 1998
1BS8
DownloadVisualize
BU of 1bs8 by Molmil
PEPTIDE DEFORMYLASE AS ZN2+ CONTAINING FORM IN COMPLEX WITH TRIPEPTIDE MET-ALA-SER
Descriptor: PROTEIN (MET-ALA-SER), PROTEIN (PEPTIDE DEFORMYLASE), SULFATE ION, ...
Authors:Becker, A, Schlichting, I, Kabsch, W, Groche, D, Schultz, S, Wagner, A.F.V.
Deposit date:1998-09-01
Release date:1999-08-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Iron center, substrate recognition and mechanism of peptide deformylase.
Nat.Struct.Biol., 5, 1998
1BS6
DownloadVisualize
BU of 1bs6 by Molmil
PEPTIDE DEFORMYLASE AS NI2+ CONTAINING FORM IN COMPLEX WITH TRIPEPTIDE MET-ALA-SER
Descriptor: NICKEL (II) ION, PROTEIN (MET-ALA-SER), PROTEIN (PEPTIDE DEFORMYLASE), ...
Authors:Becker, A, Schlichting, I, Kabsch, W, Groche, D, Schultz, S, Wagner, A.F.V.
Deposit date:1998-09-01
Release date:1999-08-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Iron center, substrate recognition and mechanism of peptide deformylase.
Nat.Struct.Biol., 5, 1998
1BS4
DownloadVisualize
BU of 1bs4 by Molmil
PEPTIDE DEFORMYLASE AS ZN2+ CONTAINING FORM (NATIVE) IN COMPLEX WITH INHIBITOR POLYETHYLENE GLYCOL
Descriptor: NONAETHYLENE GLYCOL, PROTEIN (PEPTIDE DEFORMYLASE), SULFATE ION, ...
Authors:Becker, A, Schlichting, I, Kabsch, W, Groche, D, Schultz, S, Wagner, A.F.V.
Deposit date:1998-09-01
Release date:1999-08-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Iron center, substrate recognition and mechanism of peptide deformylase.
Nat.Struct.Biol., 5, 1998
1BSZ
DownloadVisualize
BU of 1bsz by Molmil
PEPTIDE DEFORMYLASE AS FE2+ CONTAINING FORM (NATIVE) IN COMPLEX WITH INHIBITOR POLYETHYLENE GLYCOL
Descriptor: FE (III) ION, NONAETHYLENE GLYCOL, PROTEIN (PEPTIDE DEFORMYLASE), ...
Authors:Becker, A, Schlichting, I, Kabsch, W, Groche, D, Schultz, S, Wagner, A.F.V.
Deposit date:1998-09-01
Release date:1999-08-26
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Iron center, substrate recognition and mechanism of peptide deformylase.
Nat.Struct.Biol., 5, 1998
1H18
DownloadVisualize
BU of 1h18 by Molmil
Pyruvate Formate-Lyase (E.coli) in complex with Pyruvate
Descriptor: FORMATE ACETYLTRANSFERASE 1, L-TREITOL, PYRUVIC ACID, ...
Authors:Becker, A, Kabsch, W.
Deposit date:2002-07-04
Release date:2002-11-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-Ray Structure of Pyruvate Formate-Lyase in Complex with Pyruvate and Coa.How the Enzyme Uses the Cys-418 Thiyl Radical for Pyruvate Cleavage
J.Biol.Chem., 277, 2002
1ICJ
DownloadVisualize
BU of 1icj by Molmil
PDF PROTEIN IS CRYSTALLIZED AS NI2+ CONTAINING FORM, COCRYSTALLIZED WITH INHIBITOR POLYETHYLENE GLYCOL (PEG)
Descriptor: NICKEL (II) ION, NONAETHYLENE GLYCOL, PEPTIDE DEFORMYLASE, ...
Authors:Becker, A, Schlichting, I, Kabsch, W, Schultz, S, Wagner, A.F.V.
Deposit date:1998-03-12
Release date:1999-03-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of peptide deformylase and identification of the substrate binding site.
J.Biol.Chem., 273, 1998
2IVP
DownloadVisualize
BU of 2ivp by Molmil
Structure of UP1 protein
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, FE (II) ION, O-SIALOGLYCOPROTEIN ENDOPEPTIDASE
Authors:Hecker, A, Leulliot, N, Graille, M, Dorlet, P, Quevillon-Cheruel, S, Ulryck, N, Van Tilbeurgh, H, Forterre, P.
Deposit date:2006-06-14
Release date:2007-07-31
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An Archaeal Orthologue of the Universal Protein Kae1 is an Iron Metalloprotein which Exhibits Atypical DNA-Binding Properties and Apurinic-Endonuclease Activity in Vitro.
Nucleic Acids Res., 35, 2007
2IVN
DownloadVisualize
BU of 2ivn by Molmil
Structure of UP1 protein
Descriptor: GLYCEROL, MAGNESIUM ION, O-SIALOGLYCOPROTEIN ENDOPEPTIDASE, ...
Authors:Hecker, A, Leulliot, N, Graille, M, Dorlet, P, Quevillon-Cheruel, S, Ulryck, N, Van Tilbeurgh, H, Forterre, P.
Deposit date:2006-06-14
Release date:2007-07-31
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:An Archaeal Orthologue of the Universal Protein Kae1 is an Iron Metalloprotein which Exhibits Atypical DNA-Binding Properties and Apurinic-Endonuclease Activity in Vitro.
Nucleic Acids Res., 35, 2007
2IVO
DownloadVisualize
BU of 2ivo by Molmil
Structure of UP1 protein
Descriptor: TUNGSTATE(VI)ION, UP1
Authors:Hecker, A, Leulliot, N, Graille, M, Dorlet, P, Quevillon-Cheruel, S, Ulryck, N, Van Tilbeurgh, H, Forterre, P.
Deposit date:2006-06-14
Release date:2007-07-31
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:An Archaeal Orthologue of the Universal Protein Kae1 is an Iron Metalloprotein which Exhibits Atypical DNA-Binding Properties and Apurinic-Endonuclease Activity in Vitro.
Nucleic Acids Res., 35, 2007
1H16
DownloadVisualize
BU of 1h16 by Molmil
Pyruvate Formate-Lyase (E.coli) in complex with Pyruvate and CoA
Descriptor: COENZYME A, FORMATE ACETYLTRANSFERASE 1, L-TREITOL, ...
Authors:Becker, A, Kabsch, W.
Deposit date:2002-07-03
Release date:2002-11-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:X-Ray Structure of Pyruvate Formate-Lyase in Complex with Pyruvate and Coa.How the Enzyme Uses the Cys-418 Thiyl Radical for Pyruvate Cleavage
J.Biol.Chem., 277, 2002
1H17
DownloadVisualize
BU of 1h17 by Molmil
Pyruvate Formate-Lyase (E.coli) in complex with CoA and the substrate analog oxamate
Descriptor: COENZYME A, FORMATE ACETYLTRANSFERASE 1, L-TREITOL, ...
Authors:Becker, A, Kabsch, W.
Deposit date:2002-07-03
Release date:2002-11-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:X-Ray Structure of Pyruvate Formate-Lyase in Complex with Pyruvate and Coa.How the Enzyme Uses the Cys-418 Thiyl Radical for Pyruvate Cleavage
J.Biol.Chem., 277, 2002
2PFL
DownloadVisualize
BU of 2pfl by Molmil
CRYSTAL STRUCTURE OF PFL FROM E.COLI
Descriptor: CHLORIDE ION, PROTEIN (PYRUVATE FORMATE-LYASE), SODIUM ION
Authors:Becker, A, Fritz-Wolf, K, Kabsch, W, Knappe, J, Schultz, S, Wagner, A.F.V.
Deposit date:1999-05-26
Release date:1999-12-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and mechanism of the glycyl radical enzyme pyruvate formate-lyase.
Nat.Struct.Biol., 6, 1999
8CX5
DownloadVisualize
BU of 8cx5 by Molmil
Crystal Structure of small molecule alpha,beta-ketoamide 4 covalently bound to K-Ras(G12R)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAGNESIUM ION, ...
Authors:Zhang, Z, Morstein, J, Ecker, A, Guiley, K.Z, Shokat, K.M.
Deposit date:2022-05-19
Release date:2022-08-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Chemoselective Covalent Modification of K-Ras(G12R) with a Small Molecule Electrophile.
J.Am.Chem.Soc., 144, 2022
4GCJ
DownloadVisualize
BU of 4gcj by Molmil
CDK2 in complex with inhibitor RC-3-89
Descriptor: 1,2-ETHANEDIOL, 4-{[4-amino-5-(2-nitrobenzoyl)-1,3-thiazol-2-yl]amino}benzenesulfonamide, Cyclin-dependent kinase 2
Authors:Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E.
Deposit date:2012-07-30
Release date:2012-10-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases.
J.Med.Chem., 56, 2013
3R8L
DownloadVisualize
BU of 3r8l by Molmil
CDK2 in complex with inhibitor L3-4
Descriptor: (5R)-5-tert-butyl-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide, Cyclin-dependent kinase 2
Authors:Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E.
Deposit date:2011-03-24
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening
To be Published
3QZF
DownloadVisualize
BU of 3qzf by Molmil
CDK2 in complex with inhibitor JWS-6-52
Descriptor: 2-(4,6-diamino-1,3,5-triazin-2-yl)benzene-1,4-diol, Cyclin-dependent kinase 2
Authors:Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E.
Deposit date:2011-03-06
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening
To be Published
3R8P
DownloadVisualize
BU of 3r8p by Molmil
CDK2 in complex with inhibitor NSK-MC1-6
Descriptor: (5R)-5-propyl-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide, Cyclin-dependent kinase 2
Authors:Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E.
Deposit date:2011-03-24
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening
To be Published
3QQL
DownloadVisualize
BU of 3qql by Molmil
CDK2 in complex with inhibitor L3
Descriptor: (5R)-5-(2-methylbutan-2-yl)-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide, Cyclin-dependent kinase 2
Authors:Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E.
Deposit date:2011-02-15
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening
To be Published
3RM6
DownloadVisualize
BU of 3rm6 by Molmil
CDK2 in complex with inhibitor KVR-2-80
Descriptor: 1,2-ETHANEDIOL, 2-{[(2-aminopyrimidin-5-yl)methyl]amino}-5-nitro-4-{[2-(piperazin-1-yl)ethyl]amino}benzamide, Cyclin-dependent kinase 2
Authors:Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E.
Deposit date:2011-04-20
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening
To be Published

227344

数据于2024-11-13公开中

PDB statisticsPDBj update infoContact PDBjnumon