5AMT
| Intracellular growth locus protein E | Descriptor: | 1,2-ETHANEDIOL, BROMIDE ION, IGLE | Authors: | Robb, C.S, Nano, F.E, Boraston, A.B. | Deposit date: | 2015-09-01 | Release date: | 2016-10-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Cloning, Expression, Purification, Crystallization and Preliminary X-Ray Diffraction Analysis of Intracellular Growth Locus E (Igle) Protein from Francisella Tularensis Subsp. Novicida. Acta Crystallogr.,Sect.F, 66, 2010
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6HQO
| Crystal structure of GcoA F169S bound to guaiacol | Descriptor: | Cytochrome P450, Guaiacol, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Mallinson, S.J.B, Hinchen, D.J, Allen, M.D, Johnson, C.W, Beckham, G.T, McGeehan, J.E. | Deposit date: | 2018-09-25 | Release date: | 2019-07-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Enabling microbial syringol conversion through structure-guided protein engineering. Proc.Natl.Acad.Sci.USA, 116, 2019
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7LS0
| Structure of the Human ALK GRD bound to AUG | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor fused with ALK and LTK ligand 2, CITRIC ACID | Authors: | Stayrook, S, Li, T, Klein, D.E. | Deposit date: | 2021-02-17 | Release date: | 2021-11-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural basis for ligand reception by anaplastic lymphoma kinase. Nature, 600, 2021
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6HP9
| Structure of the kinase domain of human DDR1 in complex with a 2-Amino-2,3-Dihydro-1H-Indene-5-Carboxamide-based inhibitor | Descriptor: | (2~{R})-~{N}-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-2-(pyrimidin-5-ylamino)-2,3-dihydro-1~{H}-indene-5-carboxamide, Epithelial discoidin domain-containing receptor 1 | Authors: | Pinkas, D.M, Fox, A.E, Kupinska, K, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N, Structural Genomics Consortium (SGC) | Deposit date: | 2018-09-19 | Release date: | 2019-01-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | 2-Amino-2,3-dihydro-1H-indene-5-carboxamide-Based Discoidin Domain Receptor 1 (DDR1) Inhibitors: Design, Synthesis, and in Vivo Antipancreatic Cancer Efficacy. J.Med.Chem., 62, 2019
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6HQL
| Crystal structure of GcoA F169H bound to guaiacol | Descriptor: | Cytochrome P450, Guaiacol, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Mallinson, S.J.B, Hinchen, D.J, Allen, M.D, Johnson, C.W, Beckham, G.T, McGeehan, J.E. | Deposit date: | 2018-09-25 | Release date: | 2019-07-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Enabling microbial syringol conversion through structure-guided protein engineering. Proc.Natl.Acad.Sci.USA, 116, 2019
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6HQT
| Crystal structure of GcoA F169V bound to syringol | Descriptor: | 2,6-dimethoxyphenol, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Mallinson, S.J.B, Hinchen, D.J, Allen, M.D, Johnson, C.W, Beckham, G.T, McGeehan, J.E. | Deposit date: | 2018-09-25 | Release date: | 2019-07-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Enabling microbial syringol conversion through structure-guided protein engineering. Proc.Natl.Acad.Sci.USA, 116, 2019
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1Q3C
| Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli: The E2A mutant at 2.3 resolution. | Descriptor: | Endonuclease VIII, GLYCEROL, MAGNESIUM ION, ... | Authors: | Golan, G, Zharkov, D.O, Feinberg, H, Fernandes, A.S, Zaika, E.I, Kycia, J.H, Grollman, A.P, Shoham, G. | Deposit date: | 2003-07-29 | Release date: | 2004-08-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility. Nucleic Acids Res., 33, 2005
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5VWZ
| Bak in complex with Bim-h3Pc | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, AMMONIUM ION, Bcl-2 homologous antagonist/killer, ... | Authors: | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | Deposit date: | 2017-05-23 | Release date: | 2017-11-15 | Last modified: | 2020-01-08 | Method: | X-RAY DIFFRACTION (1.622 Å) | Cite: | Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
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1UTG
| REFINEMENT OF THE C2221 CRYSTAL FORM OF OXIDIZED UTEROGLOBIN AT 1.34 ANGSTROMS RESOLUTION | Descriptor: | UTEROGLOBIN | Authors: | Morize, I, Surcouf, E, Vaney, M.C, Buehner, M, Mornon, J.P. | Deposit date: | 1989-04-03 | Release date: | 1989-10-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Refinement of the C222(1) crystal form of oxidized uteroglobin at 1.34 A resolution. J.Mol.Biol., 194, 1987
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4HTI
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2VYC
| Crystal Structure of Acid Induced Arginine Decarboxylase from E. coli | Descriptor: | BIODEGRADATIVE ARGININE DECARBOXYLASE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Andrell, J, Hicks, M.G, Palmer, T, Carpenter, E.P, Iwata, S, Maher, M.J. | Deposit date: | 2008-07-22 | Release date: | 2009-03-31 | Last modified: | 2015-12-02 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of the Acid Induced Arginine Decarboxylase from Escherichia Coli: Reversible Decamer Assembly Controls Enzyme Activity. Biochemistry, 48, 2009
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4LF8
| Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | Descriptor: | 16S rRNA, MAGNESIUM ION, PAROMOMYCIN, ... | Authors: | Demirci, H, Belardinelli, R, Carr, J, Murphy IV, F, Jogl, G, Dahlberg, A.E, Gregory, S.T. | Deposit date: | 2013-06-26 | Release date: | 2014-07-02 | Method: | X-RAY DIFFRACTION (3.1484 Å) | Cite: | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus to be published, 2013
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1Q5Z
| Crystal Structure of the C-terminal Actin Binding Domain of Salmonella Invasion Protein A (SipA) | Descriptor: | SipA | Authors: | Stebbins, C.E, Lilic, M, Galkin, V.E, Orlova, A, VanLoock, M.S, Egelman, E.H. | Deposit date: | 2003-08-11 | Release date: | 2003-10-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Salmonella SipA polymerizes actin by stapling filaments with nonglobular protein arms. Science, 301, 2003
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2PII
| PII, GLNB PRODUCT | Descriptor: | PII | Authors: | Carr, P.D, Cheah, E, Suffolk, P.M, Ollis, D.L. | Deposit date: | 1995-05-02 | Release date: | 1996-06-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray structure of the signal transduction protein from Escherichia coli at 1.9 A. Acta Crystallogr.,Sect.D, 52, 1996
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1TM3
| crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59k mutant | Descriptor: | CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ... | Authors: | Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2004-06-10 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,). Biochemistry, 43, 2004
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5V91
| Crystal structure of fosfomycin resistance protein from Klebsiella pneumoniae | Descriptor: | Fosfomycin resistance protein, ZINC ION | Authors: | Klontz, E, Guenther, S, Silverstein, Z, Sundberg, E. | Deposit date: | 2017-03-22 | Release date: | 2017-08-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure and Dynamics of FosA-Mediated Fosfomycin Resistance in Klebsiella pneumoniae and Escherichia coli. Antimicrob. Agents Chemother., 61, 2017
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4HLW
| Targeting the Binding Function 3 (BF3) Site of the Human Androgen Receptor Through Virtual Screening. 2. Development of 2-((2-phenoxyethyl) thio)-1H-benzoimidazole derivatives. | Descriptor: | 2-[(2-phenoxyethyl)sulfanyl]-1H-benzimidazole, Androgen receptor, GLYCEROL, ... | Authors: | Ravi, S.N.M, Leblanc, E, Axerio-Cilies, P, Labriere, C, Frewin, K, Hassona, M.D.H, Lack, N.A, Han, F.Q, Guns, E.S, Young, R, Ban, F, Rennie, P.S, Cherkasov, A. | Deposit date: | 2012-10-17 | Release date: | 2013-01-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Targeting the Binding Function 3 (BF3) Site of the Androgen Receptor Through Virtual Screening. 2. Development of 2-((2-phenoxyethyl) thio)-1H-benzimidazole Derivatives. J.Med.Chem., 56, 2013
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2PKV
| D-(GGTATACC) ambient pressure | Descriptor: | 5'-D(*GP*GP*TP*AP*TP*AP*CP*C)-3' | Authors: | Girard, E, Prange, T, Kahn, R, Fourme, R. | Deposit date: | 2007-04-18 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Adaptation of the base-paired double-helix molecular architecture to extreme pressure. Nucleic Acids Res., 35, 2007
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1YTS
| A LIGAND-INDUCED CONFORMATIONAL CHANGE IN THE YERSINIA PROTEIN TYROSINE PHOSPHATASE | Descriptor: | SULFATE ION, YERSINIA PROTEIN TYROSINE PHOSPHATASE | Authors: | Schubert, H.L, Stuckey, J.A, Fauman, E.B, Dixon, J.E, Saper, M.A. | Deposit date: | 1995-04-07 | Release date: | 1995-07-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase. Protein Sci., 4, 1995
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1JWN
| Crystal Structure of Scapharca inaequivalvis HbI, I114F Mutant Ligated to Carbon Monoxide. | Descriptor: | CARBON MONOXIDE, Globin I - Ark Shell, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Knapp, J.E, Gibson, Q.H, Cushing, L, Royer Jr, W.E. | Deposit date: | 2001-09-04 | Release date: | 2001-12-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Restricting the ligand-linked heme movement in Scapharca dimeric hemoglobin reveals tight coupling between distal and proximal contributions to cooperativity. Biochemistry, 40, 2001
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5E69
| Glucocorticoid receptor DNA binding domain - IL8 NF-kB response element complex | Descriptor: | DNA (5'-D(*AP*TP*CP*GP*TP*GP*GP*AP*AP*TP*TP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*AP*AP*TP*TP*CP*CP*AP*CP*GP*AP*T)-3'), Glucocorticoid receptor, ... | Authors: | Hudson, W.H, Rye, E.A, Herbst, A.G, Ortlund, E.A. | Deposit date: | 2015-10-09 | Release date: | 2017-02-08 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Cryptic glucocorticoid receptor-binding sites pervade genomic NF-kappa B response elements. Nat Commun, 9, 2018
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5E6D
| Glucocorticoid receptor DNA binding domain - ICAM1 NF-kB response element complex | Descriptor: | DNA (5'-D(*GP*CP*TP*CP*CP*GP*GP*AP*AP*TP*TP*TP*CP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*GP*GP*AP*GP*C)-3'), Glucocorticoid receptor, ... | Authors: | Hudson, W.H, Rye, E.A, Herbst, A.G, Ortlund, E.A. | Deposit date: | 2015-10-09 | Release date: | 2017-02-08 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Cryptic glucocorticoid receptor-binding sites pervade genomic NF-kappa B response elements. Nat Commun, 9, 2018
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4HQI
| Structure of O6-Benzyl-2'-deoxyguanosine opposite perimidinone-derived synthetic nucleoside in DNA duplex | Descriptor: | SPERMINE, STRONTIUM ION, Short modified nucleic acids | Authors: | Kowal, E.A, Lad, R, Pallan, P.S, Muffly, E, Wawrzak, Z, Egli, M, Sturla, S.J, Stone, M.P. | Deposit date: | 2012-10-25 | Release date: | 2013-07-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Recognition of O6-benzyl-2'-deoxyguanosine by a perimidinone-derived synthetic nucleoside: a DNA interstrand stacking interaction. Nucleic Acids Res., 41, 2013
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1JEM
| NMR STRUCTURE OF HISTIDINE PHOSPHORYLATED FORM OF THE PHOSPHOCARRIER HISTIDINE CONTAINING PROTEIN FROM BACILLUS SUBTILIS, NMR, 25 STRUCTURES | Descriptor: | HISTIDINE CONTAINING PROTEIN | Authors: | Jones, B.E, Rajagopal, P, Klevit, R.E. | Deposit date: | 1997-04-01 | Release date: | 1997-07-23 | Last modified: | 2021-11-03 | Method: | SOLUTION NMR | Cite: | Phosphorylation on histidine is accompanied by localized structural changes in the phosphocarrier protein, HPr from Bacillus subtilis. Protein Sci., 6, 1997
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7WTM
| Cryo-EM structure of a yeast pre-40S ribosomal subunit - State Dis-E | Descriptor: | 18S rRNA, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ... | Authors: | Cheng, J, La Venuta, G, Lau, B, Berninghausen, O, Beckmann, R, Hurt, E. | Deposit date: | 2022-02-05 | Release date: | 2022-10-19 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | In vitro structural maturation of an early stage pre-40S particle coupled with U3 snoRNA release and central pseudoknot formation. Nucleic Acids Res., 50, 2022
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