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PDB: 41042 件

1GES
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ANATOMY OF AN ENGINEERED NAD-BINDING SITE
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE
著者Mittl, P.R.E, Schulz, G.E.
登録日1994-01-18
公開日1994-11-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Anatomy of an engineered NAD-binding site.
Protein Sci., 3, 1994
6R7F
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BU of 6r7f by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
著者Faull, S.V, Lau, A.M.C, Martens, C, Ahdash, Z, Yebenes, H, Schmidt, C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A.
登録日2019-03-28
公開日2019-08-28
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (8.2 Å)
主引用文献Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
3UJL
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Crystal structure of abscisic acid bound PYL2 in complex with type 2C protein phosphatase ABI2
分子名称: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Abscisic acid receptor PYL2, MAGNESIUM ION, ...
著者Zhou, X.E, Soon, F.-F, Ng, L.-M, Kovach, A, Tan, M.H.E, Suino-Powell, K.M, He, Y, Xu, Y, Brunzelle, J.S, Li, J, Melcher, K, Xu, H.E.
登録日2011-11-07
公開日2012-02-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases.
Science, 335, 2012
6E28
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The CARD9 CARD domain-swapped dimer
分子名称: Caspase recruitment domain-containing protein 9
著者Holliday, M.J, Ferrao, R, Boenig, G, Deuber, E.C, Fairbrother, W.J.
登録日2018-07-10
公開日2018-09-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9.
J. Biol. Chem., 293, 2018
6R8T
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Crystal structure of aIF2gamma subunit I181T from archaeon Sulfolobus solfataricus complexed with GDPCP
分子名称: FORMIC ACID, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Kravchenko, O, Arkhipova, V, Gabdulkhakov, A, Stolboushkina, E, Nikonov, O, Garber, M, Nikonov, S.
登録日2019-04-02
公開日2020-05-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of aIF2gamma subunit I181T from archaeon Sulfolobus solfataricus complexed with GDPCP
To Be Published
6TT1
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Crystal structure of 'Res_S2 mutant human Angiotensin-1 converting enzyme N-domain in complex with 33RE.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Cozier, G.E, Acharya, K.R.
登録日2019-12-23
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献ACE-domain selectivity extends beyond direct interacting residues at the active site.
Biochem.J., 477, 2020
2UY7
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Crystal structure of the P pilus rod subunit PapA
分子名称: PAP FIMBRIAL MAJOR PILIN PROTEIN, PERIPLASMID CHAPERONE PAPD PROTEIN, SULFATE ION
著者Verger, D, Bullitt, E, Hultgren, S.J, Waksman, G.
登録日2007-04-02
公開日2007-05-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the P Pilus Rod Subunit Papa.
Plos Pathog., 3, 2007
5DW7
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Crystal structure of the unliganded geosmin synthase N-terminal domain from Streptomyces coelicolor
分子名称: Germacradienol/geosmin synthase
著者Lombardi, P.M, Harris, G.G, Pemberton, T.A, Matsui, T, Weiss, T.M, Cole, K.E, Koksal, M, Murphy, F.V, Vedula, L.S, Chou, W.K, Cane, D.E, Christianson, D.W.
登録日2015-09-22
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.202 Å)
主引用文献Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with alpha alpha Domain Architecture That Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence.
Biochemistry, 54, 2015
4GT0
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Structure of dengue virus serotype 1 sE containing stem to residue 421
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, CHLORIDE ION, ...
著者Klein, D.E, Choi, J.L, Harrison, S.C.
登録日2012-08-28
公開日2012-12-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structure of a dengue virus envelope protein late-stage fusion intermediate.
J.Virol., 87, 2013
6E9R
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DHF46 filament
分子名称: DHF46 filament
著者Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D.
登録日2018-08-01
公開日2018-11-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献De novo design of self-assembling helical protein filaments.
Science, 362, 2018
2UW1
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Ivy Desaturase Structure
分子名称: (3R)-3-HYDROXY-5,5-DIMETHYLHEXANOIC ACID, FE (III) ION, PLASTID DELTA4 MULTIFUNCTIONAL ACYL-ACYL CARRIER PROTEIN DESATURASE, ...
著者Guy, J.E, Whittle, E, Kumaran, D, Lindqvist, Y, Shanklin, J.
登録日2007-03-15
公開日2007-05-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Crystal Structure of the Ivy {Delta}4-16:0-Acp Desaturase Reveals Structural Details of the Oxidized Active Site and Potential Determinants of Regioselectivity.
J.Biol.Chem., 282, 2007
1OJX
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Crystal structure of an Archaeal fructose 1,6-bisphosphate aldolase
分子名称: FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS I
著者Lorentzen, E, Zwart, P, Stark, A, Hensel, R, Siebers, B, Pohl, E.
登録日2003-07-16
公開日2003-09-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of an archaeal class I aldolase and the evolution of (betaalpha)8 barrel proteins.
J. Biol. Chem., 278, 2003
6R2N
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BU of 6r2n by Molmil
Crystal structure of KlGlk1 glucokinase from Kluyveromyces lactis
分子名称: 1,2-ETHANEDIOL, BROMIDE ION, Glucokinase-1
著者Zak, K, Wator, E, Grudnik, P.
登録日2019-03-18
公開日2019-10-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.596 Å)
主引用文献Crystal Structure of Kluyveromyces lactis Glucokinase ( Kl Glk1).
Int J Mol Sci, 20, 2019
6ZRQ
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two-protofilament amyloid structure of S20G variant of human amylin (IAPP - islet amyloid polypeptide)
分子名称: Islet amyloid polypeptide
著者Gallardo, R.U, Iadanza, M.G, Ranson, N.A, Radford, S.E.
登録日2020-07-14
公開日2020-09-30
最終更新日2020-11-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly.
Nat.Struct.Mol.Biol., 27, 2020
4GQK
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BU of 4gqk by Molmil
Structure of Native VgrG1-ACD with ADP (no cations)
分子名称: ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, VgrG protein
著者Nguyen, V.S, Spinelli, S, Derrez, E, Durand, E, Cambillau, C.
登録日2012-08-23
公開日2013-09-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structure of Native VgrG1-ACD with ADP (no cations)
To be Published
6GMO
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Plant glutamate cysteine ligase (GCL) in complex with non-reducing GSH (GSM)
分子名称: ACETATE ION, GLYCEROL, Glutamate--cysteine ligase, ...
著者Lenherr, E.D.
登録日2018-05-27
公開日2019-06-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Plant glutathione biosynthesis revisited: redox-mediated activation of glutamylcysteine ligase does not require homo-dimerization.
Biochem.J., 476, 2019
3UJG
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Crystal structure of SnRK2.6 in complex with HAB1
分子名称: MAGNESIUM ION, Protein phosphatase 2C 16, SULFATE ION, ...
著者Zhou, X.E, Soon, F.-F, Ng, L.-M, Kovach, A, Tan, M.H.E, Suino-Powell, K.M, He, Y, Xu, Y, Brunzelle, J.S, Li, J, Melcher, K, Xu, H.E.
登録日2011-11-07
公開日2012-02-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases.
Science, 335, 2012
4GR0
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Crystal structure of the catalytic domain of Human MMP12 in complex with selective phosphinic inhibitor RXP470B
分子名称: CALCIUM ION, Macrophage metalloelastase, N-[(2S)-3-[(R)-(4-bromophenyl)(hydroxy)phosphoryl]-2-{[3-(3'-chlorobiphenyl-4-yl)-1,2-oxazol-5-yl]methyl}propanoyl]-L-a lanyl-L-alaninamide, ...
著者Stura, E.A, Vera, L, Beau, F, Devel, L, Cassar-Lajeunesse, E, Dive, V.
登録日2012-08-24
公開日2013-02-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.497 Å)
主引用文献Molecular determinants of a selective matrix metalloprotease-12 inhibitor: insights from crystallography and thermodynamic studies.
J.Med.Chem., 56, 2013
8QDJ
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Ntaya virus methyltransferase in complex wih Sinefungin
分子名称: Ntaya virus methyltransferase, SINEFUNGIN, SULFATE ION
著者Krejcova, K, Boura, E, Klima, M.
登録日2023-08-29
公開日2024-09-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and functional insights in flavivirus NS5 proteins gained by the structure of Ntaya virus polymerase and methyltransferase.
Structure, 32, 2024
6ZQA
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Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state A (Poly-Ala)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
著者Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R.
登録日2020-07-09
公開日2020-09-23
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献90 S pre-ribosome transformation into the primordial 40 S subunit.
Science, 369, 2020
6BQG
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Crystal structure of 5-HT2C in complex with ergotamine
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 5-hydroxytryptamine receptor 2C,Soluble cytochrome b562, Ergotamine
著者Peng, Y, McCorvy, J.D, Harpsoe, K, Lansu, K, Yuan, S, Popov, P, Qu, L, Pu, M, Che, T, Nikolajse, L.F, Huang, X.P, Wu, Y, Shen, L, Bjorn-Yoshimoto, W.E, Ding, K, Wacker, D, Han, G.W, Cheng, J, Katritch, V, Jensen, A.A, Hanson, M.A, Zhao, S, Gloriam, D.E, Roth, B.L, Stevens, R.C, Liu, Z.
登録日2017-11-27
公開日2018-02-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.
Cell, 172, 2018
6ZRZ
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Crystal structure of 5-dimethylallyl tryptophan synthase from Streptomyces coelicolor in complex with DMASPP and Trp
分子名称: DMATS type aromatic prenyltransferase, S-(3-methylbut-2-en-1-yl) trihydrogen thiodiphosphate, TRYPTOPHAN
著者Ostertag, E, Broger, K, Stehle, T, Zocher, G.
登録日2020-07-15
公開日2020-12-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.696 Å)
主引用文献Reprogramming Substrate and Catalytic Promiscuity of Tryptophan Prenyltransferases.
J.Mol.Biol., 433, 2020
4F28
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The Crystal Structure of a Human MitoNEET mutant with Met 62 Replaced by a Gly
分子名称: CDGSH iron-sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER
著者Baxter, E.L, Zuris, J.A, Wang, C, Axelrod, H.L, Cohen, A.E, Paddock, M.L, Nechushtai, R, Onuchic, J.N, Jennings, P.A.
登録日2012-05-07
公開日2012-12-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Allosteric control in a metalloprotein dramatically alters function.
Proc.Natl.Acad.Sci.USA, 110, 2013
2P4M
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High pH structure of Rtms5 H146S variant
分子名称: GFP-like non-fluorescent chromoprotein, IODIDE ION
著者Battad, J.M, Wilmann, P.G, Olsen, S, Byres, E, Smith, S.C, Dove, S.G, Turcic, K.N, Devenish, R.J, Rossjohn, J, Prescott, M.
登録日2007-03-12
公開日2007-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structural basis for the pH-dependent increase in fluorescence efficiency of chromoproteins
J.Mol.Biol., 368, 2007
2P6X
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Crystal structure of human tyrosine phosphatase PTPN22
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Tyrosine-protein phosphatase non-receptor type 22
著者Ugochukwu, E, Salah, E, Barr, A, Shrestha, L, Alfano, I, Burgess-Brown, N, King, O, Umeano, C, Papagrigoriou, E, Pike, A.C.W, Bunkoczi, G, Turnbull, A, Uppenberg, J, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC)
登録日2007-03-19
公開日2007-04-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Cell(Cambridge,Mass.), 136, 2009

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