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PDB: 41042 件

1T39
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HUMAN O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE COVALENTLY CROSSLINKED TO DNA
分子名称: 5'-D(*GP*CP*CP*AP*TP*GP*(E1X)P*CP*TP*AP*GP*TP*A)-3', 5'-D(*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*GP*C)-3', Methylated-DNA--protein-cysteine methyltransferase
著者Daniels, D.S, Woo, T.T, Luu, K.X, Noll, D.M, Clarke, N.D, Pegg, A.E, Tainer, J.A.
登録日2004-04-25
公開日2004-07-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献DNA binding and nucleotide flipping by the human DNA repair protein AGT.
Nat.Struct.Mol.Biol., 11, 2004
2Q4D
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Ensemble refinement of the crystal structure of a lysine decarboxylase-like protein from Arabidopsis thaliana gene At5g11950
分子名称: 1,2-ETHANEDIOL, Lysine decarboxylase-like protein At5g11950, NITRATE ION
著者Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
登録日2007-05-31
公開日2007-06-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.152 Å)
主引用文献Ensemble refinement of protein crystal structures: validation and application.
Structure, 15, 2007
2Q4T
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Ensemble refinement of the protein crystal structure of a cytosolic 5'-nucleotidase III from Mus musculus Mm.158936
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cytosolic 5'-nucleotidase III
著者Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
登録日2007-05-31
公開日2007-06-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Ensemble refinement of protein crystal structures: validation and application.
Structure, 15, 2007
1MU6
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Crystal Structure of Thrombin in Complex with L-378,622
分子名称: 2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-6-PYRIDINYL)METHYL]ACETAMIDE, HIRUDIN IIB, THROMBIN
著者Burgey, C.S, Robinson, K.A, Lyle, T.A, Sanderson, P.E, Lewis, S.D, Lucas, B.J, Krueger, J.A, Singh, R, Miller-Stein, C, White, R.B, Wong, B, Lyle, E.A, Williams, P.D, Coburn, C.A, Dorsey, B.D, Barrow, J.C, Stranieri, M.T, Holahan, M.A, Sitko, G.R, Cook, J.J, McMasters, D.R, McDonough, C.M, Sanders, W.M, Wallace, A.A, Clayton, F.C, Bohn, D, Leonard, Y.M, Detwiler Jr, T.J, Lynch Jr, J.J, Yan, Y, Chen, Z, Kuo, L, Gardell, S.J, Shafer, J.A, Vacca, J.P.J.
登録日2002-09-23
公開日2004-04-06
最終更新日2021-07-21
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines.
J.Med.Chem., 46, 2003
1TM5
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crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59A mutant
分子名称: CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ...
著者Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E.
登録日2004-06-10
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,).
Biochemistry, 43, 2004
1QO1
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Molecular Architecture of the Rotary Motor in ATP Synthase from Yeast Mitochondria
分子名称: ATP SYNTHASE ALPHA CHAIN, ATP SYNTHASE BETA CHAIN, ATP SYNTHASE DELTA CHAIN, ...
著者Stock, D, Leslie, A.G.W, Walker, J.E.
登録日1999-11-01
公開日1999-11-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Molecular Architecture of the Rotary Motor in ATP Synthase
Science, 286, 1999
2PJJ
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E. coli lytic transglycosylase MltA-D308A in apo-1 form
分子名称: Membrane-bound lytic murein transglycosylase A
著者van Straaten, K.E, Dijkstra, B.W, Thunnissen, A.M.W.H.
登録日2007-04-16
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structure of Escherichia coli Lytic transglycosylase MltA with bound chitohexaose: implications for peptidoglycan binding and cleavage
J.Biol.Chem., 282, 2007
4KVB
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Thermus thermophilus HB27 30S ribosomal subunit lacking ribosomal protein S17
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Murphy, E.L, Jogl, G.
登録日2013-05-22
公開日2014-06-04
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (4.198 Å)
主引用文献Structural robustness of the ribosome inferred from the X-ray crystal structure of a 30S ribosomal subunit lacking ribosomal protein S17
To be Published
2JDN
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Mutant (S22A) of Pseudomonas aeruginosa lectin II (PA-IIL) complexed with methyl-a-L-mannopyranoside
分子名称: CALCIUM ION, FUCOSE-BINDING LECTIN PA-IIL, SULFATE ION, ...
著者Adam, J, Pokorna, M, Sabin, C, Mitchell, E.P, Imberty, A, Wimmerova, M.
登録日2007-01-11
公開日2007-06-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Engineering of Pa-Iil Lectin from Pseudomonas Aeruginosa - Unravelling the Role of the Specificity Loop for Sugar Preference.
Bmc Struct.Biol., 7, 2007
2JDU
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Mutant (G24N) of Pseudomonas aeruginosa lectin II (PA-IIL) complexed with methyl-a-L-fucopyranoside
分子名称: CALCIUM ION, FUCOSE-BINDING LECTIN PA-IIL, GLYCEROL, ...
著者Adam, J, Pokorna, M, Sabin, C, Mitchell, E.P, Imberty, A, Wimmerova, M.
登録日2007-01-12
公開日2007-06-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Engineering of Pa-Iil Lectin from Pseudomonas Aeruginosa - Unravelling the Role of the Specificity Loop for Sugar Preference.
Bmc Struct.Biol., 7, 2007
1QL6
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THE CATALYTIC MECHANISM OF PHOSPHORYLASE KINASE PROBED BY MUTATIONAL STUDIES
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PHOSPHORYLASE KINASE, ...
著者Skamnaki, V.T, Owen, D.J, Noble, M.E.M, Lowe, E.D, Oikonomakos, N.G, Johnson, L.N.
登録日1999-08-24
公開日1999-12-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Catalytic Mechanism of Phosphorylase Kinase Probed by Mutational Studies.
Biochemistry, 38, 1999
2FI4
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Crystal structure of a BPTI variant (Cys14->Ser) in complex with trypsin
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ...
著者Zakharova, E, Horvath, M.P, Goldenberg, D.P.
登録日2005-12-27
公開日2006-01-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor.
J.Mol.Biol., 382, 2008
2JDY
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Mutant (G24N) of Pseudomonas aeruginosa lectin II (PA-IIL) complexed with methyl-b-D-mannoyranoside
分子名称: CALCIUM ION, FUCOSE-BINDING LECTIN PA-IIL, methyl alpha-D-mannopyranoside
著者Adam, J, Pokorna, M, Sabin, C, Mitchell, E.P, Imberty, A, Wimmerova, M.
登録日2007-01-12
公開日2007-06-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Engineering of Pa-Iil Lectin from Pseudomonas Aeruginosa - Unravelling the Role of the Specificity Loop for Sugar Preference.
Bmc Struct.Biol., 7, 2007
1LFG
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Structure of diferric human lactoferrin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
著者Baker, E.N, Anderson, B.F, Haridas, M.
登録日1992-02-05
公開日1994-01-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of human diferric lactoferrin refined at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 51, 1995
1IRS
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IRS-1 PTB DOMAIN COMPLEXED WITH A IL-4 RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: IL-4 RECEPTOR PHOSPHOPEPTIDE, IRS-1
著者Zhou, M.-M, Huang, B, Olejniczak, E.T, Meadows, R.P, Shuker, S.B, Miyazaki, M, Trub, T, Shoelson, S.E, Feisk, S.W.
登録日1996-03-22
公開日1997-05-15
最終更新日2024-10-09
実験手法SOLUTION NMR
主引用文献Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain.
Nat.Struct.Biol., 3, 1996
2JDP
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Mutant (S23A) of Pseudomonas aeruginosa lectin II (PA-IIL) complexed with methyl-a-L-fucopyranoside
分子名称: CALCIUM ION, FUCOSE-BINDING LECTIN PA-IIL, methyl alpha-L-fucopyranoside
著者Adam, J, Pokorna, M, Sabin, C, Mitchell, E.P, Imberty, A, Wimmerova, M.
登録日2007-01-11
公開日2007-06-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Engineering of Pa-Iil Lectin from Pseudomonas Aeruginosa - Unravelling the Role of the Specificity Loop for Sugar Preference.
Bmc Struct.Biol., 7, 2007
2D69
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Crystal structure of the complex of sulfate ion and octameric ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) from Pyrococcus horikoshii OT3 (form-2 crystal)
分子名称: Ribulose bisphosphate carboxylase, SULFATE ION
著者Mizohata, E, Mishima, C, Akasaka, R, Uda, H, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-11-10
公開日2006-05-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the complex of sulfate ion and octameric ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) from Pyrococcus horikoshii OT3 (form-2 crystal)
To be Published
4M84
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Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1455
分子名称: 5-amino-1-tert-butyl-3-(quinolin-2-yl)-1H-pyrazole-4-carboxamide, Calmodulin-domain protein kinase 1
著者Merritt, E.A.
登録日2013-08-12
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Potent and selective inhibitors of CDPK1 from T. gondii and C. parvum based on a 5-aminopyrazole-4-carboxamide scaffold.
ACS Med Chem Lett, 5, 2014
1QB5
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ESCHERICHIA COLI HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER
分子名称: PROTEIN (HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER)
著者Merritt, E.A, Hol, W.G.J.
登録日1999-04-30
公開日2003-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of the B-Pentamer from E. coli Enterotoxin LT-IIb
To be Published
1URB
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ALKALINE PHOSPHATASE (N51MG)
分子名称: ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Tibbitts, T.T, Murphy, J.E, Kantrowitz, E.R.
登録日1996-02-03
公開日1996-07-11
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Kinetic and structural consequences of replacing the aspartate bridge by asparagine in the catalytic metal triad of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 257, 1996
2Q17
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Formylglycine Generating Enzyme from Streptomyces coelicolor
分子名称: CALCIUM ION, formylglycine generating enzyme
著者Carlson, B.L, Ballister, E.R, Skordalakes, E, King, D.S, Breidenbach, M.A, Gilmore, S.A, Berger, J.M, Bertozzi, C.R.
登録日2007-05-23
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Function and structure of a prokaryotic formylglycine-generating enzyme.
J.Biol.Chem., 283, 2008
2Q3T
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Ensemble refinement of the protein crystal structure of gene product from Arabidopsis thaliana At3g22680
分子名称: 1,2-ETHANEDIOL, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Protein At3g22680, ...
著者Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
登録日2007-05-30
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Ensemble refinement of protein crystal structures: validation and application.
Structure, 15, 2007
2PIU
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Androgen receptor LBD with small molecule
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID
著者Estebanez-Perpina, E, Arnold, A.A, Baxter, J.D, Webb, P, Guy, R.K, Fletterick, K.R.
登録日2007-04-13
公開日2007-09-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献A surface on the androgen receptor that allosterically regulates coactivator binding.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2GUI
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Structure and Function of Cyclized Versions of the Proofreading Exonuclease Subunit of E. coli DNA Polymerase III
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA polymerase III epsilon subunit, ...
著者Park, A.Y, Carr, P.D, Ollis, D.L, Dixon, N.E.
登録日2006-04-30
公開日2007-03-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure and Function of Cyclized Versions of the Proofreading Exonuclease Subunit E. coli DNA Polymerase III
To be Published
1LP9
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Xenoreactive complex AHIII 12.2 TCR bound to p1049/HLA-A2.1
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Buslepp, J, Wang, H, Biddison, W.E, Appella, E, Collins, E.J.
登録日2002-05-07
公開日2003-11-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A correlation between TCR Valpha docking on MHC and CD8 dependence: implications for T cell selection.
Immunity, 19, 2003

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