8V0Y
| |
6VMG
| Chloroplast ATP synthase (O3, CF1FO) | 分子名称: | ATP synthase delta chain, chloroplastic, ATP synthase epsilon chain, ... | 著者 | Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L. | 登録日 | 2020-01-27 | 公開日 | 2020-09-09 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (6.46 Å) | 主引用文献 | Structural basis of redox modulation on chloroplast ATP synthase. Commun Biol, 3, 2020
|
|
6T2W
| Crystal structure of the CSF1R kinase domain with a dihydropurinone inhibitor (compound 4) | 分子名称: | 2-[(4-methoxy-2-methyl-phenyl)amino]-7-methyl-9-(4-oxidanylcyclohexyl)purin-8-one, Macrophage colony-stimulating factor 1 receptor, SULFATE ION | 著者 | Schimpl, M, Goldberg, F.W, Finlay, M.R.V, Ting, A.K.T, Beattie, D, Lamont, G.M, Fallan, C, Wrigley, G.L, Howard, M.R, Williamson, B, Davies, B.R, Cadogan, E.B, Ramos-Montoya, A, Dean, E. | 登録日 | 2019-10-09 | 公開日 | 2020-01-01 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Discovery of 7-Methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one (AZD7648), a Potent and Selective DNA-Dependent Protein Kinase (DNA-PK) Inhibitor. J.Med.Chem., 63, 2020
|
|
8UZX
| |
1K7H
| CRYSTAL STRUCTURE OF SHRIMP ALKALINE PHOSPHATASE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALKALINE PHOSPHATASE, MALEIC ACID, ... | 著者 | De Backer, M.E, Mc Sweeney, S, Rasmussen, H.B, Riise, B.W, Lindley, P, Hough, E. | 登録日 | 2001-10-19 | 公開日 | 2002-07-31 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | The 1.9 A Crystal Structure of Heat-Labile Shrimp Alkaline Phosphatase J.Mol.Biol., 318, 2002
|
|
4U5D
| Crystal structure of GluA2, con-ikot-ikot snail toxin, partial agonist KA and postitive modulator (R,R)-2b complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Con-ikot-ikot, ... | 著者 | Chen, L, Gouaux, E. | 登録日 | 2014-07-25 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.5757 Å) | 主引用文献 | X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism. Science, 345, 2014
|
|
4U5H
| |
4FEW
| Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor pyrazolopyrimidine PP2 | 分子名称: | 1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, ACETATE ION, Aminoglycoside 3'-phosphotransferase AphA1-IAB, ... | 著者 | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Minasov, G, Egorova, O, Di Leo, R, Shakya, T, Spanogiannopoulos, P, Wright, G.D, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-05-30 | 公開日 | 2012-06-20 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Biochem.J., 454, 2013
|
|
4KTG
| |
4FJW
| |
4ZV9
| 2.00 Angstrom resolution crystal structure of an uncharacterized protein from Escherichia coli O157:H7 str. Sakai | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, PHOSPHATE ION, ... | 著者 | Halavaty, A.S, Wawrzak, Z, Filippova, E.V, Kiryukhina, O, Endres, M, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-05-18 | 公開日 | 2015-06-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 2.00 Angstrom resolution crystal structure of an uncharacterized protein from Escherichia coli O157:H7 str. Sakai To Be Published
|
|
6C05
| Mycobacterium tuberculosis RNAP Holo/RbpA in relaxed state | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M. | 登録日 | 2017-12-27 | 公開日 | 2018-03-28 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (5.15 Å) | 主引用文献 | Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7, 2018
|
|
4TX4
| Crystal Structure of a Single-Domain Cysteine Protease Inhibitor from Cowpea (Vigna unguiculata) | 分子名称: | Cysteine proteinase inhibitor, SULFATE ION | 著者 | Pereira, H.M, Valadares, N, Monteiro-Junior, J.E, Carvalho, C.P.S, Grangeiro, T.B. | 登録日 | 2014-07-02 | 公開日 | 2015-10-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Expression in Escherichia coli of cysteine protease inhibitors from cowpea (Vigna unguiculata): The crystal structure of a single-domain cystatin gives insights on its thermal and pH stability. Int. J. Biol. Macromol., 102, 2017
|
|
2VAE
| Fast maturing red fluorescent protein, DsRed.T4 | 分子名称: | 1,2-ETHANEDIOL, RED FLUORESCENT PROTEIN | 著者 | Strongin, D.E, Bevis, B, Khuong, N, Downing, M.E, Strack, R.L, Sundaram, K, Glick, B.S, Keenan, R.J. | 登録日 | 2007-08-31 | 公開日 | 2007-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Structural Rearrangements Near the Chromophore Influence the Maturation Speed and Brightness of Dsred Variants. Protein Eng.Des.Sel., 20, 2007
|
|
4U21
| GluA2flip sLBD complexed with FW and (R,R)-2b crystal form E | 分子名称: | 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide | 著者 | Chen, L, Gouaux, E. | 登録日 | 2014-07-16 | 公開日 | 2014-08-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.3908 Å) | 主引用文献 | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States. Cell, 158, 2014
|
|
1Z62
| Indirubin-3'-aminooxy-acetate inhibits glycogen phosphorylase by binding at the inhibitor and the allosteric site. Broad specificities of the two sites | 分子名称: | ({[(3E)-2'-OXO-2',7'-DIHYDRO-2,3'-BIINDOL-3(7H)-YLIDENE]AMINO}OXY)ACETIC ACID, Glycogen phosphorylase, muscle form, ... | 著者 | Kosmopoulou, M.N, Leonidas, D.D, Chrysina, E.D, Eisenbrand, G, Oikonomakos, N.G. | 登録日 | 2005-03-21 | 公開日 | 2006-03-07 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Indirubin-3'-Aminooxy-Acetate Inhibits Glycogen Phosphorylase by Binding at the Inhibitor and the Allosteric Site. Broad Specificities of the Two Sites LETT.DRUG DES.DISCOVERY, 2, 2005
|
|
5US1
| Crystal structure of aminoglycoside acetyltransferase AAC(2')-Ia in complex with N2'-acetylgentamicin C1A and coenzyme A | 分子名称: | (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-(acetylamino)-6-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranoside, ACETYL COENZYME *A, Aminoglycoside 2'-N-acetyltransferase, ... | 著者 | Stogios, P.J, Evdokimova, E, Xu, Z, Wawrzak, Z, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-02-13 | 公開日 | 2017-03-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes. ACS Infect Dis, 4, 2018
|
|
8PZQ
| Model for focused reconstruction of influenza A RNP-like particle | 分子名称: | Nucleoprotein, RNA (5'P-(UC)6-FAM3') | 著者 | Chenavier, F, Estrozi, L.F, Zarkadas, E, Ruigrok, R.W.H, Schoehn, G, Ballandras-Colas, A, Crepin, T. | 登録日 | 2023-07-27 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | 主引用文献 | Cryo-EM structure of influenza helical nucleocapsid reveals NP-NP and NP-RNA interactions as a model for the genome encapsidation. Sci Adv, 9, 2023
|
|
8V5C
| IpaD (122-321) Bound to Deoxycholate | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GLYCEROL, Invasin IpaD | 著者 | Barker, S.A, Dickenson, N.E, Johnson, S.J. | 登録日 | 2023-11-30 | 公開日 | 2024-08-21 | 最終更新日 | 2024-09-18 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structural and functional characterization of the IpaD pi-helix reveals critical roles in DOC interaction, T3SS apparatus maturation, and Shigella virulence. J.Biol.Chem., 300, 2024
|
|
6WQ2
| Cryo-EM of the S. islandicus filamentous virus, SIFV | 分子名称: | A-DNA, Structural protein MCP1, Structural protein MCP2 | 著者 | Wang, F, Baquero, D.P, Su, Z, Zheng, W, Prangishvili, D, Krupovic, M, Egelman, E.H. | 登録日 | 2020-04-28 | 公開日 | 2020-07-29 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of filamentous viruses infecting hyperthermophilic archaea explain DNA stabilization in extreme environments. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
5DFS
| Crystal structure of Spider Monkey Cytochrome C at 1.15 Angstrom | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Cytochrome c, ... | 著者 | MOU, T.C, McClelland, L.J, Jeakins-Cooley, M.E, Goldes, M.E, SPRANG, S.R, BOWLER, B.E. | 登録日 | 2015-08-27 | 公開日 | 2016-03-02 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Disruption of a hydrogen bond network in human versus spider monkey cytochrome c affects heme crevice stability. J.Inorg.Biochem., 158, 2016
|
|
4H2E
| Crystal structure of an MMP twin inhibitor complexing two MMP-9 catalytic domains | 分子名称: | ACETATE ION, BICINE, CALCIUM ION, ... | 著者 | Stura, E.A, Vera, L, Cassar-Lajeunesse, E, Nuti, E, Catalani, M.P, Dive, V, Rossello, A. | 登録日 | 2012-09-12 | 公開日 | 2013-04-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.902 Å) | 主引用文献 | Crystallization of bi-functional ligand protein complexes. J.Struct.Biol., 182, 2013
|
|
5KR1
| Protease PR5-DRV | 分子名称: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease PR5-DRV | 著者 | Liu, Z, Poole, K.M, Mahon, B.P, McKenna, R, Fanucci, G.E. | 登録日 | 2016-07-06 | 公開日 | 2016-09-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Effects of Hinge-region Natural Polymorphisms on Human Immunodeficiency Virus-Type 1 Protease Structure, Dynamics, and Drug Pressure Evolution. J.Biol.Chem., 291, 2016
|
|
2OHJ
| Crystal Structure of coenzyme F420H2 oxidase (FprA), a diiron flavoprotein, inactive oxidized state | 分子名称: | CHLORIDE ION, FE (III) ION, FLAVIN MONONUCLEOTIDE, ... | 著者 | Seedorf, H, Warkentin, E, Ermler, U. | 登録日 | 2007-01-10 | 公開日 | 2007-05-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Structure of coenzyme F420H2 oxidase (FprA), a di-iron flavoprotein from methanogenic Archaea catalyzing the reduction of O2 to H2O. Febs J., 274, 2007
|
|
6BRW
| JAK2 JH2 in complex with XMU-MP-1 | 分子名称: | 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide, ACETATE ION, GLYCEROL, ... | 著者 | Puleo, D.E, Schlessinger, J. | 登録日 | 2017-12-01 | 公開日 | 2018-08-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.031 Å) | 主引用文献 | JAK2 JH2 Binders To Be Published
|
|