6BRW

JAK2 JH2 in complex with XMU-MP-1

Summary for 6BRW

• Entry DOI: 10.2210/pdb6brw/pdb
• Descriptor: Tyrosine-protein kinase JAK2, 4-[(5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide, GLYCEROL, ... (5 entities in total)
• Functional Keywords: pseudokinase domain, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 33688.58

Authors

Puleo, D.E.,Schlessinger, J. (deposition date: 2017-12-01, release date: 2018-08-15, Last modification date: 2023-10-04)

• Primary citation: Puleo, D.E.,Schlessinger, J.; JAK2 JH2 Binders; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.031 Å)