6BRW
JAK2 JH2 in complex with XMU-MP-1
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue 5BS A 901 |
| Chain | Residue |
| A | LEU551 |
| A | SER633 |
| A | LYS677 |
| A | ASN678 |
| A | LEU680 |
| A | SER698 |
| A | LEU579 |
| A | LYS581 |
| A | GLN626 |
| A | GLU627 |
| A | PHE628 |
| A | VAL629 |
| A | LYS630 |
| A | GLY632 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 902 |
| Chain | Residue |
| A | ILE682 |
| A | ARG683 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 903 |
| Chain | Residue |
| A | ASN673 |
| A | ARG715 |
| A | TRP718 |
| A | HOH1060 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Site: {"description":"Breakpoint for translocation to form PCM1-JAK2 fusion protein"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
