2WDR
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![BU of 2wdr by Molmil](/molmil-images/mine/2wdr) | E. coli succinate:quinone oxidoreductase (SQR) with pentachlorophenol bound | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Ruprecht, J, Yankovskaya, V, Maklashina, E, Iwata, S, Cecchini, G. | 登録日 | 2009-03-25 | 公開日 | 2009-08-25 | 最終更新日 | 2015-02-04 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of Escherichia Coli Succinate:Quinone Oxidoreductase with an Occupied and Empty Quinone- Binding Site. J.Biol.Chem., 284, 2009
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5WHU
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![BU of 5whu by Molmil](/molmil-images/mine/5whu) | Crystal structure of 3'SL bound ArtB | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ArtB protein, ... | 著者 | Gao, X, Galan, J.E. | 登録日 | 2017-07-18 | 公開日 | 2017-10-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Evolution of host adaptation in the Salmonella typhoid toxin. Nat Microbiol, 2, 2017
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5WJW
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![BU of 5wjw by Molmil](/molmil-images/mine/5wjw) | Cryo-EM structure of B. subtilis flagellar filaments H84R | 分子名称: | Flagellin | 著者 | Wang, F, Burrage, A.M, Orlova, A, Kearns, D.B, Egelman, E.H. | 登録日 | 2017-07-24 | 公開日 | 2017-10-25 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
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6GOD
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![BU of 6god by Molmil](/molmil-images/mine/6god) | KRAS full length wild-type GPPNHP | 分子名称: | GLYCEROL, GTPase KRas, MAGNESIUM ION, ... | 著者 | Cruz-Migoni, A, Quevedo, C.E, Carr, S.B, Ehebauer, M.T, Phillips, S.V.E, Rabbitts, T.H. | 登録日 | 2018-06-01 | 公開日 | 2019-02-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5K4W
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![BU of 5k4w by Molmil](/molmil-images/mine/5k4w) | Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei bound to NADH and L-threonine refined to 1.72 angstroms | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, L-threonine 3-dehydrogenase, ... | 著者 | Adjogatse, E.A, Erskine, P.T, Cooper, J.B. | 登録日 | 2016-05-22 | 公開日 | 2018-01-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta Crystallogr D Struct Biol, 74, 2018
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6BOK
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![BU of 6bok by Molmil](/molmil-images/mine/6bok) | |
5NG2
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![BU of 5ng2 by Molmil](/molmil-images/mine/5ng2) | |
6FQQ
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6BOY
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![BU of 6boy by Molmil](/molmil-images/mine/6boy) | Crystal structure of DDB1-CRBN-BRD4(BD1) complex bound to dBET6 PROTAC. | 分子名称: | 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-(8-{[({2-[(3S)-2,6-dioxopiperidin-3-yl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}oxy)acetyl]amino}octyl)acetamide, Bromodomain-containing protein 4, DNA damage-binding protein 1, ... | 著者 | Nowak, R.P, DeAngelo, S.L, Buckley, D, Bradner, J.E, Fischer, E.S. | 登録日 | 2017-11-21 | 公開日 | 2018-05-30 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | 主引用文献 | Plasticity in binding confers selectivity in ligand-induced protein degradation. Nat. Chem. Biol., 14, 2018
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5NNK
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6WF3
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![BU of 6wf3 by Molmil](/molmil-images/mine/6wf3) | Crystal structure of human Naa50 in complex with a cofactor derived inhibitor (compound 1) | 分子名称: | ACE-MET-LEU-GLY-PRO-NH2, COENZYME A, N-alpha-acetyltransferase 50 | 著者 | Greasley, S.E, Feng, J, Deng, Y.-L, Stewart, A.E. | 登録日 | 2020-04-03 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.291 Å) | 主引用文献 | Characterization of SpecificN-alpha-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library. Acs Med.Chem.Lett., 11, 2020
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6FMS
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![BU of 6fms by Molmil](/molmil-images/mine/6fms) | IMISX-EP of Se-LspA | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Globomycin, Lipoprotein signal peptidase | 著者 | Huang, C.-Y, Olieric, V, Howe, N, Warshamanage, R, Weinert, T, Panepucci, E, Vogeley, L, Basu, S, Diederichs, K, Caffrey, M, Wang, M. | 登録日 | 2018-02-02 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | In situ serial crystallography for rapid de novo membrane protein structure determination. Commun Biol, 1, 2018
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6HZU
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![BU of 6hzu by Molmil](/molmil-images/mine/6hzu) | HUMAN JAK1 IN COMPLEX WITH LASW1393 | 分子名称: | 2-[4-[8-oxidanylidene-2-[(~{E})-(2-oxidanylidenepyridin-3-ylidene)amino]-7~{H}-purin-9-yl]cyclohexyl]ethanenitrile, Tyrosine-protein kinase JAK1 | 著者 | Lozoya, E, Segarra, V, Bach, J, Jestel, A, Lammens, A, Blaesse, M. | 登録日 | 2018-10-24 | 公開日 | 2019-10-23 | 最終更新日 | 2019-11-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Identification of 2-Imidazopyridine and 2-Aminopyridone Purinones as Potent Pan-Janus Kinase (JAK) Inhibitors for the Inhaled Treatment of Respiratory Diseases. J.Med.Chem., 62, 2019
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5FU7
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![BU of 5fu7 by Molmil](/molmil-images/mine/5fu7) | drosophila nanos NBR peptide bound to the NOT module of the human CCR4-NOT complex | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3, ... | 著者 | Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E. | 登録日 | 2016-01-21 | 公開日 | 2016-03-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos Embo J., 35, 2016
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8ADU
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![BU of 8adu by Molmil](/molmil-images/mine/8adu) | Lipidic alpha-synuclein fibril - polymorph L1A | 分子名称: | Alpha-synuclein | 著者 | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | 登録日 | 2022-07-11 | 公開日 | 2022-10-12 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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6X25
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![BU of 6x25 by Molmil](/molmil-images/mine/6x25) | CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 1-PHOSPHATASE INPP1 IN COMPLEX GADOLINIUM AFTER ADDITION OF INOSITOL 1,3,4-TRISPHOSPHATE AND LITHIUM AT 3.2 ANGSTROM RESOLUTION | 分子名称: | GADOLINIUM ATOM, Inositol polyphosphate 1-phosphatase, SULFATE ION | 著者 | Dollins, D.E, Endo-Streeter, S, Ren, Y, York, J.D. | 登録日 | 2020-05-20 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | A structural basis for lithium and substrate binding of an inositide phosphatase. J.Biol.Chem., 296, 2020
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6GXZ
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![BU of 6gxz by Molmil](/molmil-images/mine/6gxz) | Crystal structure of the human RPAP3(TPR2)-PIH1D1(CS) complex | 分子名称: | CALCIUM ION, PIH1 domain-containing protein 1, RNA polymerase II-associated protein 3 | 著者 | Henri, J, Quinternet, M, Manival, X, Chagot, M.-E, Charpentier, B, Meyer, P. | 登録日 | 2018-06-27 | 公開日 | 2018-08-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.965 Å) | 主引用文献 | Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex. Structure, 26, 2018
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5WHT
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![BU of 5wht by Molmil](/molmil-images/mine/5wht) | Crystal structure of 3'SL bound PltB | 分子名称: | ACETATE ION, DI(HYDROXYETHYL)ETHER, N-acetyl-alpha-neuraminic acid, ... | 著者 | Gao, X, Galan, J.E. | 登録日 | 2017-07-18 | 公開日 | 2017-10-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.932 Å) | 主引用文献 | Evolution of host adaptation in the Salmonella typhoid toxin. Nat Microbiol, 2, 2017
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4YB7
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![BU of 4yb7 by Molmil](/molmil-images/mine/4yb7) | Adenosine triphosphate phosphoribosyltransferase from Campylobacter jejuni in complex with ATP | 分子名称: | ACETIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ATP phosphoribosyltransferase, ... | 著者 | Mittelstaedt, G, Moggre, G.-J, Parker, E.J. | 登録日 | 2015-02-18 | 公開日 | 2016-03-09 | 最終更新日 | 2018-09-05 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Campylobacter jejuni adenosine triphosphate phosphoribosyltransferase is an active hexamer that is allosterically controlled by the twisting of a regulatory tail. Protein Sci., 25, 2016
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8ADS
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![BU of 8ads by Molmil](/molmil-images/mine/8ads) | Lipidic alpha-synuclein fibril - polymorph L2B | 分子名称: | Alpha-synuclein | 著者 | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | 登録日 | 2022-07-11 | 公開日 | 2022-10-12 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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5NG0
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![BU of 5ng0 by Molmil](/molmil-images/mine/5ng0) | Structure of RIP2K(L294F) with bound AMPPCP | 分子名称: | COBALT (II) ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | 著者 | Pellegrini, E, Cusack, S. | 登録日 | 2017-03-16 | 公開日 | 2017-06-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation. PLoS ONE, 12, 2017
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8POB
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![BU of 8pob by Molmil](/molmil-images/mine/8pob) | Crystal structure of Hen Egg White Lysozyme co-crystallized with 10 mM TbXo4-SO3 | 分子名称: | 6-[[4-[(6-carboxypyridin-2-yl)methyl]-7-(3-sulfopropyl)-1,4,7-triazonan-1-yl]methyl]pyridine-2-carboxylic acid, CHLORIDE ION, Lysozyme C, ... | 著者 | Alsalman, Z, Girard, E. | 登録日 | 2023-07-04 | 公開日 | 2024-07-10 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Influence of Chemical Modifications of the Crystallophore on Protein Nucleating Properties and Supramolecular Interactions Network. Chemistry, 30, 2024
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5NG3
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![BU of 5ng3 by Molmil](/molmil-images/mine/5ng3) | Structure of inactive kinase RIP2K(K47R) | 分子名称: | Receptor-interacting serine/threonine-protein kinase 2, SULFATE ION | 著者 | Pellegrini, E, Cusack, S. | 登録日 | 2017-03-16 | 公開日 | 2017-06-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation. PLoS ONE, 12, 2017
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8J3S
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![BU of 8j3s by Molmil](/molmil-images/mine/8j3s) | Complex structure of human cytomegalovirus protease and a macrocyclic peptide ligand | 分子名称: | Assemblin, PHE-ILE-THR-GLY-HIS-TYR-TRP-VAL-ARG-PHE-LEU-PRO-CYS-GLY | 著者 | Yoshida, S, Sako, Y, Nikaido, E, Ueda, T, Kozono, I, Ichihashi, Y, Nakahashi, A, Onishi, M, Yamatsu, Y, Kato, T, Nishikawa, J, Tachibana, Y. | 登録日 | 2023-04-18 | 公開日 | 2023-11-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of beta-Herpesvirus Proteases. Acs Med.Chem.Lett., 14, 2023
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2O72
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![BU of 2o72 by Molmil](/molmil-images/mine/2o72) | |