8J3S
Complex structure of human cytomegalovirus protease and a macrocyclic peptide ligand
Summary for 8J3S
| Entry DOI | 10.2210/pdb8j3s/pdb |
| Descriptor | Assemblin, PHE-ILE-THR-GLY-HIS-TYR-TRP-VAL-ARG-PHE-LEU-PRO-CYS-GLY (3 entities in total) |
| Functional Keywords | protease, hydrolase |
| Biological source | Human betaherpesvirus 5 More |
| Total number of polymer chains | 7 |
| Total formula weight | 121619.69 |
| Authors | Yoshida, S.,Sako, Y.,Nikaido, E.,Ueda, T.,Kozono, I.,Ichihashi, Y.,Nakahashi, A.,Onishi, M.,Yamatsu, Y.,Kato, T.,Nishikawa, J.,Tachibana, Y. (deposition date: 2023-04-18, release date: 2023-11-08, Last modification date: 2023-11-29) |
| Primary citation | Yoshida, S.,Sako, Y.,Nikaido, E.,Ueda, T.,Kozono, I.,Ichihashi, Y.,Nakahashi, A.,Onishi, M.,Yamatsu, Y.,Kato, T.,Nishikawa, J.,Tachibana, Y. Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of beta-Herpesvirus Proteases. Acs Med.Chem.Lett., 14:1558-1566, 2023 Cited by PubMed: 37974946DOI: 10.1021/acsmedchemlett.3c00359 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.09 Å) |
Structure validation
Download full validation report
