2EBI
 
 | | Arabidopsis GT-1 DNA-binding domain with T133D phosphomimetic mutation | | Descriptor: | DNA binding protein GT-1 | | Authors: | Nagata, T, Noto, K, Niyada, E, Ikeda, Y, Yamamoto, Y, Uesugi, S, Murata, J, Hiratsuka, K, Katahira, M. | | Deposit date: | 2007-02-08 | | Release date: | 2008-02-19 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the trihelix DNA-binding domains of the wild-type and a phosphomimetic mutant of Arabidopsis GT-1: mechanism for an increase in DNA-binding affinity through phosphorylation.
Proteins, 78, 2010
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5W60
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5W52
 | | MicroED structure of the segment, DLIIKGISVHI, from the RRM2 of TDP-43, residues 247-257 | | Descriptor: | TAR DNA-binding protein 43 | | Authors: | Guenther, E.L, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | | Deposit date: | 2017-06-13 | | Release date: | 2018-02-21 | | Last modified: | 2024-04-03 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.4 Å) | | Cite: | Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.
Nat. Struct. Mol. Biol., 25, 2018
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5W61
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8QUC
 | | Cryo-EM Structure of Human Kv3.1 in Complex with Modulator AUT1 | | Descriptor: | (5R)-5-ethyl-3-[6-(3-methoxy-4-methyl-phenoxy)pyridin-3-yl]imidazolidine-2,4-dione, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Chi, G, Mckinley, G, Marsden, B, Pike, A.C.W, Ye, M, Brooke, L.M, Bakshi, S, Pilati, N, Marasco, A, Gunthorpe, M, Alvaro, G, Large, C, Lakshminaraya, B, Williams, E, Sauer, D.B. | | Deposit date: | 2023-10-16 | | Release date: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | The binding and mechanism of a positive allosteric modulator of Kv3 channels.
Nat Commun, 15, 2024
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5VR5
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5VWL
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8S03
 | | NMR solution structure of the CysD2 domain of MUC2 | | Descriptor: | CALCIUM ION, Mucin-2 | | Authors: | Recktenwald, C, Karlsson, B.G, Garcia-Bonnete, M.-J, Katona, G, Jensen, M, Lymer, R, Baeckstroem, M, Johansson, M.E.V, Hansson, G.C, Trillo-Muyo, S. | | Deposit date: | 2024-02-13 | | Release date: | 2024-04-17 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based cross-linking.
Cell Rep, 43, 2024
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2E1X
 | | NMR structure of the HIV-2 nucleocapsid protein | | Descriptor: | Gag-Pol polyprotein (Pr160Gag-Pol), ZINC ION | | Authors: | Matsui, T, Kodera, Y, Miyauchi, E, Tanaka, H, Endoh, H, Komatsu, H, Tanaka, T, Kohno, T, Maeda, T. | | Deposit date: | 2006-11-03 | | Release date: | 2007-06-05 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | Structural role of the secondary active domain of HIV-2 NCp8 in multi-functionality
Biochem.Biophys.Res.Commun., 358, 2007
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1A15
 | | SDF-1ALPHA | | Descriptor: | STROMAL DERIVED FACTOR-1ALPHA, SULFATE ION | | Authors: | Dealwis, C.G, Fernandez, E.J, Lolis, E. | | Deposit date: | 1997-12-22 | | Release date: | 1998-08-12 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of chemically synthesized [N33A] stromal cell-derived factor 1alpha, a potent ligand for the HIV-1 "fusin" coreceptor.
Proc.Natl.Acad.Sci.USA, 95, 1998
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4U9M
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199L
 | | THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME | | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME | | Authors: | Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W. | | Deposit date: | 1995-11-06 | | Release date: | 1996-03-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme.
J.Mol.Biol., 259, 1996
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1A1Q
 | | HEPATITIS C VIRUS NS3 PROTEINASE | | Descriptor: | NS3 PROTEINASE, ZINC ION | | Authors: | Love, R.A, Parge, H.E, Wickersham, J.A, Hostomsky, Z, Habuka, N, Moomaw, E.W, Adachi, T, Hostomska, Z. | | Deposit date: | 1997-12-12 | | Release date: | 1998-03-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site.
Cell(Cambridge,Mass.), 87, 1996
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195L
 | | THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME | | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME | | Authors: | Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W. | | Deposit date: | 1995-11-06 | | Release date: | 1996-03-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme.
J.Mol.Biol., 259, 1996
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2EC7
 | | Solution Structure of Human Immunodificiency Virus Type-2 Nucleocapsid Protein | | Descriptor: | Gag polyprotein (Pr55Gag), ZINC ION | | Authors: | Matsui, T, Kodera, Y, Tanaka, T, Endoh, H, Tanaka, H, Miyauchi, E, Komatsu, H, Kohno, T, Maeda, T. | | Deposit date: | 2007-02-10 | | Release date: | 2008-02-19 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The RNA recognition mechanism of human immunodeficiency virus (HIV) type 2 NCp8 is different from that of HIV-1 NCp7
Biochemistry, 48, 2009
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2ERC
 | | CRYSTAL STRUCTURE OF ERMC' A RRNA-METHYL TRANSFERASE | | Descriptor: | RRNA METHYL TRANSFERASE | | Authors: | Bussiere, D.E, Muchmore, S.W, Dealwis, C.G, Schluckebier, G, Abad-Zapatero, C. | | Deposit date: | 1998-03-13 | | Release date: | 1999-03-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.03 Å) | | Cite: | Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria.
Biochemistry, 37, 1998
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2ESY
 | | Structure and influence on stability and activity of the N-terminal propetide part of lung surfactant protein C | | Descriptor: | lung surfactant protein C | | Authors: | Li, J, Liepinsh, E, Almlen, A, Thyberg, J, Curstedt, T, Jornvall, H, Johansson, J. | | Deposit date: | 2005-10-27 | | Release date: | 2005-11-15 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | Structure and influence on stability and activity of the N-terminal propeptide part of lung surfactant protein C
Febs J., 273, 2006
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2ESK
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2EUN
 | | Cytochrome c peroxidase (CCP) in complex with 2,4-diaminopyrimidine | | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, PYRIMIDINE-2,4-DIAMINE, cytochrome c peroxidase | | Authors: | Brenk, R, Vetter, S.W, Boyce, S.E, Goodin, D.B, Shoichet, B.K. | | Deposit date: | 2005-10-29 | | Release date: | 2006-04-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Probing molecular docking in a charged model binding site.
J.Mol.Biol., 357, 2006
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196L
 | | THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME | | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME | | Authors: | Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W. | | Deposit date: | 1995-11-06 | | Release date: | 1996-03-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme.
J.Mol.Biol., 259, 1996
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4UIF
 | | Cryo-EM structure of Dengue virus serotype 2 in complex with antigen-binding fragments of human antibody 2D22 | | Descriptor: | ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - LIGHT CHAIN, DENGUE VIRUS SEROTYPE 2 STRAIN PVP94 07 - ENVELOPE PROTEIN, ... | | Authors: | Fibriansah, G, Ibarra, K.D, Ng, T.-S, Smith, S.A, Tan, J.L, Lim, X.-N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe Junior, J.E, Lok, S.-M. | | Deposit date: | 2015-03-30 | | Release date: | 2015-07-15 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6.5 Å) | | Cite: | Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers.
Science, 349, 2015
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1AXS
 | | MATURE OXY-COPE CATALYTIC ANTIBODY WITH HAPTEN | | Descriptor: | (1S,2S,5S)2-(4-GLUTARIDYLBENZYL)-5-PHENYL-1-CYCLOHEXANOL, CADMIUM ION, OXY-COPE CATALYTIC ANTIBODY | | Authors: | Mundorff, E.C, Ulrich, H.D, Stevens, R.C. | | Deposit date: | 1997-10-20 | | Release date: | 1998-02-04 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The interplay between binding energy and catalysis in the evolution of a catalytic antibody.
Nature, 389, 1997
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5HP0
 | | Solution Structure of TAZ2-p53AD2 | | Descriptor: | CREB-binding protein,Cellular tumor antigen p53 fusion protein, ZINC ION | | Authors: | Krois, A.S, Ferreon, J.C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | | Deposit date: | 2016-01-19 | | Release date: | 2016-03-16 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
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4EER
 | | Crystal structure of LOV2 domain of Arabidopsis thaliana phototropin 2 C426A mutant | | Descriptor: | FLAVIN MONONUCLEOTIDE, Phototropin-2 | | Authors: | Hitomi, K, Christie, J.M, Arvai, A.S, Hartfield, K.A, Pratt, A.J, Tainer, J.A, Getzoff, E.D. | | Deposit date: | 2012-03-28 | | Release date: | 2012-05-16 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.753 Å) | | Cite: | Structural Tuning of the Fluorescent Protein iLOV for Improved Photostability.
J.Biol.Chem., 287, 2012
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4TNV
 | | C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab in a non-conducting conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, CHLORIDE ION, ... | | Authors: | Althoff, T, Hibbs, R.E, Banerjee, S, Gouaux, E. | | Deposit date: | 2014-06-05 | | Release date: | 2014-08-13 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.
Nature, 512, 2014
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