6OUV
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5FAY
| Y208F mutant of choline TMA-lyase | 分子名称: | CHOLINE ION, Choline trimethylamine-lyase, MALONATE ION, ... | 著者 | Funk, M.A, Drennan, C.L. | 登録日 | 2015-12-12 | 公開日 | 2016-09-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase. Cell Chem Biol, 23, 2016
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5FAU
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5FAW
| T502A mutant of choline TMA-lyase | 分子名称: | CHOLINE ION, Choline trimethylamine-lyase, MALONATE ION, ... | 著者 | Funk, M.A, Drennan, C.L. | 登録日 | 2015-12-12 | 公開日 | 2016-09-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.852 Å) | 主引用文献 | Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase. Cell Chem Biol, 23, 2016
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5FAV
| E491Q mutant of choline TMA-lyase | 分子名称: | Choline trimethylamine-lyase, MALONATE ION, SODIUM ION | 著者 | Funk, M.A, Drennan, C.L. | 登録日 | 2015-12-12 | 公開日 | 2016-09-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase. Cell Chem Biol, 23, 2016
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1L1L
| CRYSTAL STRUCTURE OF B-12 DEPENDENT (CLASS II) RIBONUCLEOTIDE REDUCTASE | 分子名称: | RIBONUCLEOSIDE TRIPHOSPHATE REDUCTASE | 著者 | Sintchak, M.D, Arjara, G, Kellogg, B.A, Stubbe, J, Drennan, C.L. | 登録日 | 2002-02-18 | 公開日 | 2002-04-10 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The crystal structure of class II ribonucleotide reductase reveals how an allosterically regulated monomer mimics a dimer. Nat.Struct.Biol., 9, 2002
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4DJD
| Crystal structure of folate-free corrinoid iron-sulfur protein (CFeSP) in complex with its methyltransferase (MeTr) | 分子名称: | 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase, CALCIUM ION, COBALAMIN, ... | 著者 | Kung, Y, Doukov, T.I, Blasiak, L.C, Drennan, C.L. | 登録日 | 2012-02-01 | 公開日 | 2012-03-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Visualizing molecular juggling within a B12-dependent methyltransferase complex. Nature, 484, 2012
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4DJF
| Crystal structure of folate-bound corrinoid iron-sulfur protein (CFeSP) in complex with its methyltransferase (MeTr), co-crystallized with folate and Ti(III) citrate reductant | 分子名称: | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase, CALCIUM ION, ... | 著者 | Kung, Y, Drennan, C.L. | 登録日 | 2012-02-01 | 公開日 | 2012-03-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | Visualizing molecular juggling within a B12-dependent methyltransferase complex. Nature, 484, 2012
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8V9I
| 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Deinococcus radiodurans with D-phenylalanine-derived triazole acetylphosphonate (D-PheTrAP) bound | 分子名称: | 1-deoxy-D-xylulose-5-phosphate synthase, 2-HYDROXY BUTANE-1,4-DIOL, 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(1S)-1-[(S)-(2-{1-[(1R)-1-carboxy-2-phenylethyl]-1H-1,2,3-triazol-4-yl}ethoxy)(hydroxy)phosphoryl]-1-hydroxyethyl}-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, ... | 著者 | Chen, P.Y.-T, Drennan, C.L. | 登録日 | 2023-12-08 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | 主引用文献 | Potent Inhibition of E. coli DXP Synthase by a gem -Diaryl Bisubstrate Analog. Acs Infect Dis., 10, 2024
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7KQ4
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7KQ3
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2OAL
| RebH with bound FAD | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Tryptophan halogenase | 著者 | Blasiak, L.C, Drennan, C.L. | 登録日 | 2006-12-16 | 公開日 | 2007-02-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Chlorination by a long-lived intermediate in the mechanism of flavin-dependent halogenases Biochemistry, 46, 2007
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2OAM
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2OGY
| Asn199Ala Mutant of the 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase complexed with methyltetrahydrofolate to 2.3 Angstrom resolution | 分子名称: | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase, CALCIUM ION | 著者 | Doukov, T.I, Drennan, C.L, Hemmi, H, Ragsdale, S.W. | 登録日 | 2007-01-09 | 公開日 | 2007-01-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and kinetic evidence for an extended hydrogen-bonding network in catalysis of methyl group transfer. Role of an active site asparagine residue in activation of methyl transfer by methyltransferases. J.Biol.Chem., 282, 2007
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7LHR
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7LHU
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7LHS
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3UUS
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3UBY
| Crystal structure of human alklyadenine DNA glycosylase in a lower and higher-affinity complex with DNA | 分子名称: | DNA (5'-D(*GP*AP*CP*AP*TP*GP*(EDC)P*TP*TP*GP*CP*CP*T)-3'), DNA-3-methyladenine glycosylase | 著者 | Setser, J.W, Lingaraju, G.M, Davis, C.A, Samson, L.D, Drennan, C.L. | 登録日 | 2011-10-25 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Searching for DNA lesions: structural evidence for lower- and higher-affinity DNA binding conformations of human alkyladenine DNA glycosylase. Biochemistry, 51, 2012
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3U33
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6OWR
| NMR solution structure of YfiD | 分子名称: | Autonomous glycyl radical cofactor | 著者 | Bowman, S.E.J, Drennan, C.L. | 登録日 | 2019-05-10 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme. J.Biol.Inorg.Chem., 24, 2019
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4ERM
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4DJE
| Crystal structure of folate-bound corrinoid iron-sulfur protein (CFeSP) in complex with its methyltransferase (MeTr), co-crystallized with folate | 分子名称: | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase, CALCIUM ION, ... | 著者 | Kung, Y, Drennan, C.L. | 登録日 | 2012-02-01 | 公開日 | 2012-03-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.504 Å) | 主引用文献 | Visualizing molecular juggling within a B12-dependent methyltransferase complex. Nature, 484, 2012
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6ONS
| Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase with the D-cluster ligating cysteines mutated to alanines, coexpressed with CooC, as-isolated | 分子名称: | Carbon monoxide dehydrogenase, FE(4)-NI(1)-S(4) CLUSTER, IRON/SULFUR CLUSTER | 著者 | Cohen, S.E, Wittenborn, E.C, Drennan, C.L. | 登録日 | 2019-04-22 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.485 Å) | 主引用文献 | Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase. J.Biol.Chem., 294, 2019
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4ERP
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