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PDB: 234 件

6OUV
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1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Deinococcus radiodurans with methylacetylphosphonate (MAP) bound
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1S)-1-HYDROXY-1-[(R)-HYDROXY(METHOXY)PHOSPHORYL]ETHYL}-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, MAGNESIUM ION, ...
著者Chen, P.Y.-T, Drennan, C.L.
登録日2019-05-05
公開日2019-07-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.937 Å)
主引用文献X-ray crystallography-based structural elucidation of enzyme-bound intermediates along the 1-deoxy-d-xylulose 5-phosphate synthase reaction coordinate.
J.Biol.Chem., 294, 2019
5FAY
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Y208F mutant of choline TMA-lyase
分子名称: CHOLINE ION, Choline trimethylamine-lyase, MALONATE ION, ...
著者Funk, M.A, Drennan, C.L.
登録日2015-12-12
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase.
Cell Chem Biol, 23, 2016
5FAU
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BU of 5fau by Molmil
wild-type choline TMA lyase in complex with choline
分子名称: CHOLINE ION, Choline trimethylamine-lyase, GLYCEROL
著者Funk, M.A, Drennan, C.L.
登録日2015-12-12
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase.
Cell Chem Biol, 23, 2016
5FAW
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BU of 5faw by Molmil
T502A mutant of choline TMA-lyase
分子名称: CHOLINE ION, Choline trimethylamine-lyase, MALONATE ION, ...
著者Funk, M.A, Drennan, C.L.
登録日2015-12-12
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.852 Å)
主引用文献Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase.
Cell Chem Biol, 23, 2016
5FAV
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BU of 5fav by Molmil
E491Q mutant of choline TMA-lyase
分子名称: Choline trimethylamine-lyase, MALONATE ION, SODIUM ION
著者Funk, M.A, Drennan, C.L.
登録日2015-12-12
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase.
Cell Chem Biol, 23, 2016
1L1L
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BU of 1l1l by Molmil
CRYSTAL STRUCTURE OF B-12 DEPENDENT (CLASS II) RIBONUCLEOTIDE REDUCTASE
分子名称: RIBONUCLEOSIDE TRIPHOSPHATE REDUCTASE
著者Sintchak, M.D, Arjara, G, Kellogg, B.A, Stubbe, J, Drennan, C.L.
登録日2002-02-18
公開日2002-04-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The crystal structure of class II ribonucleotide reductase reveals how an allosterically regulated monomer mimics a dimer.
Nat.Struct.Biol., 9, 2002
4DJD
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BU of 4djd by Molmil
Crystal structure of folate-free corrinoid iron-sulfur protein (CFeSP) in complex with its methyltransferase (MeTr)
分子名称: 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase, CALCIUM ION, COBALAMIN, ...
著者Kung, Y, Doukov, T.I, Blasiak, L.C, Drennan, C.L.
登録日2012-02-01
公開日2012-03-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Visualizing molecular juggling within a B12-dependent methyltransferase complex.
Nature, 484, 2012
4DJF
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Crystal structure of folate-bound corrinoid iron-sulfur protein (CFeSP) in complex with its methyltransferase (MeTr), co-crystallized with folate and Ti(III) citrate reductant
分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase, CALCIUM ION, ...
著者Kung, Y, Drennan, C.L.
登録日2012-02-01
公開日2012-03-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Visualizing molecular juggling within a B12-dependent methyltransferase complex.
Nature, 484, 2012
8V9I
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1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Deinococcus radiodurans with D-phenylalanine-derived triazole acetylphosphonate (D-PheTrAP) bound
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, 2-HYDROXY BUTANE-1,4-DIOL, 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(1S)-1-[(S)-(2-{1-[(1R)-1-carboxy-2-phenylethyl]-1H-1,2,3-triazol-4-yl}ethoxy)(hydroxy)phosphoryl]-1-hydroxyethyl}-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, ...
著者Chen, P.Y.-T, Drennan, C.L.
登録日2023-12-08
公開日2024-04-24
実験手法X-RAY DIFFRACTION (1.981 Å)
主引用文献Potent Inhibition of E. coli DXP Synthase by a gem -Diaryl Bisubstrate Analog.
Acs Infect Dis., 10, 2024
7KQ4
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BU of 7kq4 by Molmil
Structure of isethionate sulfite-lyase from Bilophila wadsworthia with glycerol bound
分子名称: GLYCEROL, Isethionate sulfite-lyase
著者Dawson, C.D, Backman, L.R.F, Drennan, C.L.
登録日2020-11-13
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.261 Å)
主引用文献Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase.
Cell Chem Biol, 28, 2021
7KQ3
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BU of 7kq3 by Molmil
Structure of isethionate sulfite-lyase from Bilophila wadsworthia with substrate isethionate bound
分子名称: 2-hydroxyethylsulfonic acid, Isethionate sulfite-lyase
著者Dawson, C.D, Backman, L.R.F, Drennan, C.L.
登録日2020-11-13
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.688 Å)
主引用文献Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase.
Cell Chem Biol, 28, 2021
2OAL
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BU of 2oal by Molmil
RebH with bound FAD
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Tryptophan halogenase
著者Blasiak, L.C, Drennan, C.L.
登録日2006-12-16
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Chlorination by a long-lived intermediate in the mechanism of flavin-dependent halogenases
Biochemistry, 46, 2007
2OAM
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Apo RebH from Lechevalieria aerocolonigenes
分子名称: Tryptophan halogenase
著者Blasiak, L.C, Drennan, C.L.
登録日2006-12-16
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Chlorination by a long-lived intermediate in the mechanism of flavin-dependent halogenases(,).
Biochemistry, 46, 2007
2OGY
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BU of 2ogy by Molmil
Asn199Ala Mutant of the 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase complexed with methyltetrahydrofolate to 2.3 Angstrom resolution
分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase, CALCIUM ION
著者Doukov, T.I, Drennan, C.L, Hemmi, H, Ragsdale, S.W.
登録日2007-01-09
公開日2007-01-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and kinetic evidence for an extended hydrogen-bonding network in catalysis of methyl group transfer. Role of an active site asparagine residue in activation of methyl transfer by methyltransferases.
J.Biol.Chem., 282, 2007
7LHR
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BU of 7lhr by Molmil
Crystal structure of adenosine-5'-phosphosulfate reductase from Mycobacterium tuberculosis
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, IRON/SULFUR CLUSTER, Phosphoadenosine phosphosulfate reductase
著者Feliciano, P.R, Drennan, C.L.
登録日2021-01-26
公開日2021-07-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Crystal Structure of the [4Fe-4S] Cluster-Containing Adenosine-5'-phosphosulfate Reductase from Mycobacterium tuberculosis .
Acs Omega, 6, 2021
7LHU
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BU of 7lhu by Molmil
Crystal structure of adenosine-5'-phosphosulfate reductase from Mycobacterium tuberculosis in a complex with product AMP
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE MONOPHOSPHATE, IRON/SULFUR CLUSTER, ...
著者Feliciano, P.R, Drennan, C.L.
登録日2021-01-26
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Crystal Structure of the [4Fe-4S] Cluster-Containing Adenosine-5'-phosphosulfate Reductase from Mycobacterium tuberculosis .
Acs Omega, 6, 2021
7LHS
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BU of 7lhs by Molmil
Crystal structure of adenosine-5'-phosphosulfate reductase from Mycobacterium tuberculosis in a complex with substrate APS
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-PHOSPHOSULFATE, IRON/SULFUR CLUSTER, ...
著者Feliciano, P.R, Drennan, C.L.
登録日2021-01-26
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Crystal Structure of the [4Fe-4S] Cluster-Containing Adenosine-5'-phosphosulfate Reductase from Mycobacterium tuberculosis .
Acs Omega, 6, 2021
3UUS
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BU of 3uus by Molmil
Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit alpha, ...
著者Zimanyi, C.M, Drennan, C.L.
登録日2011-11-28
公開日2011-12-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (5.65 Å)
主引用文献Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase.
Proc.Natl.Acad.Sci.USA, 108, 2011
3UBY
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BU of 3uby by Molmil
Crystal structure of human alklyadenine DNA glycosylase in a lower and higher-affinity complex with DNA
分子名称: DNA (5'-D(*GP*AP*CP*AP*TP*GP*(EDC)P*TP*TP*GP*CP*CP*T)-3'), DNA-3-methyladenine glycosylase
著者Setser, J.W, Lingaraju, G.M, Davis, C.A, Samson, L.D, Drennan, C.L.
登録日2011-10-25
公開日2011-12-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Searching for DNA lesions: structural evidence for lower- and higher-affinity DNA binding conformations of human alkyladenine DNA glycosylase.
Biochemistry, 51, 2012
3U33
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BU of 3u33 by Molmil
Crystal Structure of the E. coli adaptive response protein AidB in the space group P3(2)
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Putative acyl-CoA dehydrogenase AidB
著者Wong, C, Jost, M, Drennan, C.L.
登録日2011-10-04
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Flavin-induced oligomerization in Escherichia coli adaptive response protein AidB.
Biochemistry, 50, 2011
6OWR
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BU of 6owr by Molmil
NMR solution structure of YfiD
分子名称: Autonomous glycyl radical cofactor
著者Bowman, S.E.J, Drennan, C.L.
登録日2019-05-10
公開日2019-07-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme.
J.Biol.Inorg.Chem., 24, 2019
4ERM
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BU of 4erm by Molmil
Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex at 4 Angstroms resolution
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Zimanyi, C.M, Drennan, C.L.
登録日2012-04-20
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase.
Structure, 20, 2012
4DJE
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BU of 4dje by Molmil
Crystal structure of folate-bound corrinoid iron-sulfur protein (CFeSP) in complex with its methyltransferase (MeTr), co-crystallized with folate
分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase, CALCIUM ION, ...
著者Kung, Y, Drennan, C.L.
登録日2012-02-01
公開日2012-03-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.504 Å)
主引用文献Visualizing molecular juggling within a B12-dependent methyltransferase complex.
Nature, 484, 2012
6ONS
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BU of 6ons by Molmil
Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase with the D-cluster ligating cysteines mutated to alanines, coexpressed with CooC, as-isolated
分子名称: Carbon monoxide dehydrogenase, FE(4)-NI(1)-S(4) CLUSTER, IRON/SULFUR CLUSTER
著者Cohen, S.E, Wittenborn, E.C, Drennan, C.L.
登録日2019-04-22
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.485 Å)
主引用文献Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase.
J.Biol.Chem., 294, 2019
4ERP
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BU of 4erp by Molmil
Crystal structure of a gemcitabine-diphosphate inhibited E. coli class Ia ribonucleotide reductase complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MU-OXO-DIIRON, Ribonucleoside-diphosphate reductase 1 subunit alpha, ...
著者Zimanyi, C.M, Drennan, C.L.
登録日2012-04-20
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.45 Å)
主引用文献Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase.
Structure, 20, 2012

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