2OGY

Asn199Ala Mutant of the 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase complexed with methyltetrahydrofolate to 2.3 Angstrom resolution

Summary for 2OGY

Entry DOI	10.2210/pdb2ogy/pdb
Related	1AD4 1AJ0 1F6Y 1Q8J 1TWW 1TX0
Descriptor	5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase, CALCIUM ION, 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, ... (4 entities in total)
Functional Keywords	methyltetrahydrofolate-protein complex, corrionoid, vitamin b12, tim barrel, transferase
Biological source	Moorella thermoacetica
Total number of polymer chains	2
Total formula weight	58189.26
Authors	Doukov, T.I.,Drennan, C.L.,Hemmi, H.,Ragsdale, S.W. (deposition date: 2007-01-09, release date: 2007-01-23, Last modification date: 2023-08-30)
Primary citation	Doukov, T.I.,Hemmi, H.,Drennan, C.L.,Ragsdale, S.W. Structural and kinetic evidence for an extended hydrogen-bonding network in catalysis of methyl group transfer. Role of an active site asparagine residue in activation of methyl transfer by methyltransferases. J.Biol.Chem., 282:6609-6618, 2007 Cited by PubMed: 17172470 DOI: 10.1074/jbc.M609828200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation