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PDB: 110 results
1VC0
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Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Imidazole and Sr2+ solution
Descriptor: Hepatitis Delta virus ribozyme, STRONTIUM ION, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC6
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BU of 1vc6 by Molmil
Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Product with C75U Mutaion, cleaved in Imidazole and Mg2+ solutions
Descriptor: Hepatitis Delta virus ribozyme, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-04
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VBX
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BU of 1vbx by Molmil
Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in EDTA solution
Descriptor: Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC5
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BU of 1vc5 by Molmil
Crystal Structure of the Wild Type Hepatitis Delta Virus Gemonic Ribozyme Precursor, in EDTA solution
Descriptor: Hepatitis Delta virus ribozyme, SODIUM ION, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-04
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VBZ
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BU of 1vbz by Molmil
Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Ba2+ solution
Descriptor: BARIUM ION, Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
5VGB
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BU of 5vgb by Molmil
Crystal structure of NmeCas9 HNH domain bound to anti-CRISPR AcrIIC1
Descriptor: Anti-CRISPR protein (AcrIIC1), CRISPR-associated endonuclease Cas9, GLYCEROL, ...
Authors:Harrington, L.B, Doxzen, K.W, Ma, E, Knott, G.J, Kranzusch, P.J, Doudna, J.A.
Deposit date:2017-04-10
Release date:2017-08-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:A Broad-Spectrum Inhibitor of CRISPR-Cas9.
Cell, 170, 2017
5VVL
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BU of 5vvl by Molmil
Cas1-Cas2 bound to full-site mimic with Ni
Descriptor: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (11-MER), ...
Authors:Wright, A.V, Knott, G.J, Doxzen, K.D, Doudna, J.A.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Structures of the CRISPR genome integration complex.
Science, 357, 2017
5VZL
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BU of 5vzl by Molmil
cryo-EM structure of the Cas9-sgRNA-AcrIIA4 anti-CRISPR complex
Descriptor: CRISPR-associated endonuclease Cas9, phage anti-CRISPR AcrIIA4, single guide RNA (116-MER)
Authors:Jiang, F, Liu, J.J, Nogales, E, Doudna, J.A.
Deposit date:2017-05-29
Release date:2017-07-26
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Disabling Cas9 by an anti-CRISPR DNA mimic.
Sci Adv, 3, 2017
5UX0
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BU of 5ux0 by Molmil
X-ray crystal structure of Marinitoga piezophila Argonaute in complex with 5' OH guide RNA and target DNA
Descriptor: Argonaute protein, DNA (5'-D(P*AP*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*CP*C)-3'), RNA (5'-R(*G*GP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*AP*U)-3')
Authors:Doxzen, K.W, Doudna, J.A.
Deposit date:2017-02-21
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.197 Å)
Cite:DNA recognition by an RNA-guided bacterial Argonaute.
PLoS ONE, 12, 2017
5W1H
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BU of 5w1h by Molmil
Crystal structure of LbaCas13a (C2c2) bound to mature crRNA (24-nt spacer)
Descriptor: GLYCEROL, IODIDE ION, LbaCas13a (C2c2), ...
Authors:Knott, G.J, Doudna, J.A.
Deposit date:2017-06-03
Release date:2017-09-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.
Nat. Struct. Mol. Biol., 24, 2017
5VVK
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BU of 5vvk by Molmil
Cas1-Cas2 bound to full-site mimic
Descriptor: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (5'-D(*GP*AP*CP*CP*AP*CP*CP*AP*GP*TP*G)-3'), ...
Authors:Wright, A.V, Knott, G.J, Doxzen, K.D, Doudna, J.A.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of the CRISPR genome integration complex.
Science, 357, 2017
5VVJ
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Cas1-Cas2 bound to half-site intermediate
Descriptor: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (112-MER), ...
Authors:Wright, A.V, Knott, G.J, Doxzen, K.W, Doudna, J.A.
Deposit date:2017-05-19
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.89 Å)
Cite:Structures of the CRISPR genome integration complex.
Science, 357, 2017
5W1I
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BU of 5w1i by Molmil
Crystal structure of LbaCas13a (C2c2) bound to mature crRNA (20-nt spacer)
Descriptor: IODIDE ION, LbaCas13a (C2c2), mature crRNA
Authors:Knott, G.J, Doudna, J.A.
Deposit date:2017-06-03
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.
Nat. Struct. Mol. Biol., 24, 2017
5WFE
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BU of 5wfe by Molmil
Cas1-Cas2-IHF-DNA holo-complex
Descriptor: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ...
Authors:Wright, A.V, Liu, J.J, Nogales, E, Doudna, J.A.
Deposit date:2017-07-11
Release date:2017-08-02
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Structures of the CRISPR genome integration complex.
Science, 357, 2017
5WLH
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BU of 5wlh by Molmil
Crystal structure of LbaCas13a H328A (C2c2) bound to pre-crRNA (24-nt spacer)
Descriptor: GLYCEROL, IODIDE ION, LbaCas13a H328A (C2c2), ...
Authors:Knott, G.J, Doudna, J.A.
Deposit date:2017-07-26
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.80001032 Å)
Cite:Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.
Nat. Struct. Mol. Biol., 24, 2017
4C9D
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BU of 4c9d by Molmil
Cas6 (TTHB231) product complex
Descriptor: CAS6B, R3 REPEAT RNA CLEAVAGE PRODUCT
Authors:Jinek, M, Niewoehner, O, Doudna, J.A.
Deposit date:2013-10-02
Release date:2013-11-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.
Nucleic Acids Res., 42, 2014
4C8Z
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BU of 4c8z by Molmil
Cas6 (TTHA0078) product complex
Descriptor: CAS6A, POTASSIUM ION, R1 REPEAT RNA CLEAVAGE PRODUCT, ...
Authors:Jinek, M, Niewoehner, O, Doudna, J.A.
Deposit date:2013-10-02
Release date:2013-11-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Evolution of Crispr RNA Recognition and Processing by Cas6 Endonucleases.
Nucleic Acids Res., 42, 2014
4C8Y
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BU of 4c8y by Molmil
Cas6 (TTHA0078) substrate mimic complex
Descriptor: CAS6A, R1 REPEAT RNA SUBSTRATE MIMIC, SULFATE ION
Authors:Jinek, M, Niewoehner, O, Doudna, J.A.
Deposit date:2013-10-02
Release date:2013-11-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Evolution of Crispr RNA Recognition and Processing by Cas6 Endonucleases.
Nucleic Acids Res., 42, 2014
4C98
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BU of 4c98 by Molmil
Thermus thermophilus Cas6 (TTHB231)
Descriptor: CAS6B, ZINC ION
Authors:Jinek, M, Niewoehner, O, Doudna, J.A.
Deposit date:2013-10-02
Release date:2013-11-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Evolution of Crispr RNA Recognition and Processing by Cas6 Endonucleases.
Nucleic Acids Res., 42, 2014
4AN8
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BU of 4an8 by Molmil
Structure of Thermus thermophilus CasA (Cse1)
Descriptor: ACETATE ION, CSE1
Authors:Sashital, D.G, Wiedenheft, B, Doudna, J.A.
Deposit date:2012-03-16
Release date:2012-05-02
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of Foreign DNA Selection in a Bacterial Adaptive Immune System.
Mol.Cell, 46, 2012
4C97
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BU of 4c97 by Molmil
Cas6 (TTHA0078) H37A mutant
Descriptor: CAS6A, SULFATE ION
Authors:Jinek, M, Niewoehner, O, Doudna, J.A.
Deposit date:2013-10-02
Release date:2013-11-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Evolution of Crispr RNA Recognition and Processing by Cas6 Endonucleases.
Nucleic Acids Res., 42, 2014
4AL5
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BU of 4al5 by Molmil
Crystal structure of the Csy4-crRNA product complex
Descriptor: 5'-R(*UP*UP*CP*AP*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP *GP*GP*CP*AP*GP*C)-3', CSY4 ENDORIBONUCLEASE, GLYCEROL
Authors:Haurwitz, R.E, Sternberg, S.H, Doudna, J.A.
Deposit date:2012-03-02
Release date:2012-06-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA.
Embo J., 31, 2012
4AL6
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BU of 4al6 by Molmil
Crystal structure of the S148ACsy4-crRNA complex
Descriptor: CRRNA, 5'-R(CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP* CP*AP*GP*C)-3', CSY4 ENDORIBONUCLEASE
Authors:Haurwitz, R.E, Sternberg, S.H, Doudna, J.A.
Deposit date:2012-03-02
Release date:2012-06-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA.
Embo J., 31, 2012
4CMQ
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BU of 4cmq by Molmil
Crystal structure of Mn-bound S.pyogenes Cas9
Descriptor: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION
Authors:Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A.
Deposit date:2014-01-17
Release date:2014-02-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation
Science, 343, 2014
4AL7
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BU of 4al7 by Molmil
Crystal structure of the Csy4-minimal crRNA complex
Descriptor: 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*AP*G)-3', CSY4 ENDORIBONUCLEASE
Authors:Haurwitz, R.E, Sternberg, S.H, Doudna, J.A.
Deposit date:2012-03-02
Release date:2012-06-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA.
Embo J., 31, 2012

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