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PDB: 155 results
5UX0
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X-ray crystal structure of Marinitoga piezophila Argonaute in complex with 5' OH guide RNA and target DNA
Descriptor: Argonaute protein, DNA (5'-D(P*AP*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*CP*C)-3'), RNA (5'-R(*G*GP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*AP*U)-3')
Authors:Doxzen, K.W, Doudna, J.A.
Deposit date:2017-02-21
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.197 Å)
Cite:DNA recognition by an RNA-guided bacterial Argonaute.
PLoS ONE, 12, 2017
1VC0
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BU of 1vc0 by Molmil
Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Imidazole and Sr2+ solution
Descriptor: Hepatitis Delta virus ribozyme, STRONTIUM ION, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC6
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BU of 1vc6 by Molmil
Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Product with C75U Mutaion, cleaved in Imidazole and Mg2+ solutions
Descriptor: Hepatitis Delta virus ribozyme, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-04
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1SJ4
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BU of 1sj4 by Molmil
Crystal structure of a C75U mutant Hepatitis Delta Virus ribozyme precursor, in Cu2+ solution
Descriptor: precursor form of the Hepatitis Delta virus ribozyme, small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H, Doudna, J.A.
Deposit date:2004-03-02
Release date:2004-05-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
Nature, 429, 2004
1VBX
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BU of 1vbx by Molmil
Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in EDTA solution
Descriptor: Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC5
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Crystal Structure of the Wild Type Hepatitis Delta Virus Gemonic Ribozyme Precursor, in EDTA solution
Descriptor: Hepatitis Delta virus ribozyme, SODIUM ION, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-04
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VBZ
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BU of 1vbz by Molmil
Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Ba2+ solution
Descriptor: BARIUM ION, Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
4AN8
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BU of 4an8 by Molmil
Structure of Thermus thermophilus CasA (Cse1)
Descriptor: ACETATE ION, CSE1
Authors:Sashital, D.G, Wiedenheft, B, Doudna, J.A.
Deposit date:2012-03-16
Release date:2012-05-02
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of Foreign DNA Selection in a Bacterial Adaptive Immune System.
Mol.Cell, 46, 2012
2Y35
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BU of 2y35 by Molmil
Crystal structure of Xrn1-substrate complex
Descriptor: DT11 (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP)-3', LD22664P, MAGNESIUM ION
Authors:Jinek, M, Coyle, S.M, Doudna, J.A.
Deposit date:2010-12-18
Release date:2011-03-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Coupled 5' Nucleotide Recognition and Processivity in Xrn1-Mediated Mrna Decay.
Mol.Cell, 41, 2011
1DRZ
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BU of 1drz by Molmil
U1A SPLICEOSOMAL PROTEIN/HEPATITIS DELTA VIRUS GENOMIC RIBOZYME COMPLEX
Descriptor: MAGNESIUM ION, PROTEIN (U1 SMALL RIBONUCLEOPROTEIN A), RNA (HEPATITIS DELTA VIRUS GENOMIC RIBOZYME), ...
Authors:Ferre-D'Amare, A.R, Zhou, K, Doudna, J.A.
Deposit date:1998-09-01
Release date:1999-02-16
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a hepatitis delta virus ribozyme.
Nature, 395, 1998
1KXK
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BU of 1kxk by Molmil
Crystal Structure of a RNA Molecule Containing Domain 5 and 6 of the Yeast ai5g Group II Self-splicing Intron
Descriptor: MAGNESIUM ION, ai5g group II Self-splicing intron
Authors:Zhang, L, Doudna, J.A.
Deposit date:2002-01-31
Release date:2002-03-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into group II intron catalysis and branch-site selection.
Science, 295, 2002
3P2Q
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BU of 3p2q by Molmil
Crystal structure of the fluoroacetyl-CoA-specific thioesterase, FlK
Descriptor: Fluoroacetyl coenzyme A thioesterase
Authors:Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
Deposit date:2010-10-03
Release date:2010-10-20
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
4C98
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BU of 4c98 by Molmil
Thermus thermophilus Cas6 (TTHB231)
Descriptor: CAS6B, ZINC ION
Authors:Jinek, M, Niewoehner, O, Doudna, J.A.
Deposit date:2013-10-02
Release date:2013-11-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Evolution of Crispr RNA Recognition and Processing by Cas6 Endonucleases.
Nucleic Acids Res., 42, 2014
2Y8Y
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BU of 2y8y by Molmil
Structure B of CRISPR endoribonuclease Cse3 bound to 19 nt RNA
Descriptor: 5'-R(*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP *GP*GP*DGP*AP*U)-3', CSE3
Authors:Sashital, D.G, Jinek, M, Doudna, J.A.
Deposit date:2011-02-11
Release date:2011-05-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:An RNA-Induced Conformational Change Required for Crispr RNA Cleavage by the Endoribonuclease Cse3.
Nat.Struct.Mol.Biol., 18, 2011
2Y8W
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BU of 2y8w by Molmil
Structure of CRISPR endoribonuclease Cse3 bound to 20 nt RNA
Descriptor: 5'-R(*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP *GP*GP*DGP*AP*UP*G)-3', CSE3
Authors:Sashital, D.G, Jinek, M, Doudna, J.A.
Deposit date:2011-02-11
Release date:2011-05-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:An RNA-Induced Conformational Change Required for Crispr RNA Cleavage by the Endoribonuclease Cse3.
Nat.Struct.Mol.Biol., 18, 2011
3P2S
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BU of 3p2s by Molmil
Crystal structure of the fluoroacetyl-CoA-specific thioesterase FlK in an open conformation
Descriptor: Fluoroacetyl coenzyme A thioesterase
Authors:Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
Deposit date:2010-10-04
Release date:2010-10-20
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
4OGC
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BU of 4ogc by Molmil
Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii
Descriptor: ACETATE ION, HNH endonuclease domain protein, MAGNESIUM ION, ...
Authors:Jiang, F, Ma, E, Lin, S, Doudna, J.A.
Deposit date:2014-01-15
Release date:2014-02-12
Last modified:2014-03-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Science, 343, 2014
4C9D
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BU of 4c9d by Molmil
Cas6 (TTHB231) product complex
Descriptor: CAS6B, R3 REPEAT RNA CLEAVAGE PRODUCT
Authors:Jinek, M, Niewoehner, O, Doudna, J.A.
Deposit date:2013-10-02
Release date:2013-11-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.
Nucleic Acids Res., 42, 2014
4C8Z
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BU of 4c8z by Molmil
Cas6 (TTHA0078) product complex
Descriptor: CAS6A, POTASSIUM ION, R1 REPEAT RNA CLEAVAGE PRODUCT, ...
Authors:Jinek, M, Niewoehner, O, Doudna, J.A.
Deposit date:2013-10-02
Release date:2013-11-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Evolution of Crispr RNA Recognition and Processing by Cas6 Endonucleases.
Nucleic Acids Res., 42, 2014
4C8Y
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BU of 4c8y by Molmil
Cas6 (TTHA0078) substrate mimic complex
Descriptor: CAS6A, R1 REPEAT RNA SUBSTRATE MIMIC, SULFATE ION
Authors:Jinek, M, Niewoehner, O, Doudna, J.A.
Deposit date:2013-10-02
Release date:2013-11-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Evolution of Crispr RNA Recognition and Processing by Cas6 Endonucleases.
Nucleic Acids Res., 42, 2014
2XLJ
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BU of 2xlj by Molmil
Crystal structure of the Csy4-crRNA complex, hexagonal form
Descriptor: 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*A*DG*C)-3', CSY4 ENDORIBONUCLEASE
Authors:Haurwitz, R.E, Jinek, M, Wiedenheft, B, Zhou, K, Doudna, J.A.
Deposit date:2010-07-20
Release date:2010-09-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Sequence- and Structure-Specific RNA Processing by a Crispr Endonuclease.
Science, 329, 2010
2XLK
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BU of 2xlk by Molmil
Crystal structure of the Csy4-crRNA complex, orthorhombic form
Descriptor: 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*A*DG*C)-3', CSY4 ENDORIBONUCLEASE
Authors:Haurwitz, R.E, Jinek, M, Wiedenheft, B, Zhou, K, Doudna, J.A.
Deposit date:2010-07-21
Release date:2010-09-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.805 Å)
Cite:Sequence- and Structure-Specific RNA Processing by a Crispr Endonuclease.
Science, 329, 2010
2XLI
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BU of 2xli by Molmil
Crystal structure of the Csy4-crRNA complex, monoclinic form
Descriptor: 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*A*DG*C)-3', CSY4 ENDORIBONUCLEASE
Authors:Haurwitz, R.E, Jinek, M, Wiedenheft, B, Zhou, K, Doudna, J.A.
Deposit date:2010-07-20
Release date:2010-09-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Sequence- and Structure-Specific RNA Processing by a Crispr Endonuclease.
Science, 329, 2010
4OGE
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BU of 4oge by Molmil
Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii
Descriptor: HNH endonuclease domain protein, MAGNESIUM ION, SPERMIDINE, ...
Authors:Jiang, F, Ma, E, Lin, S, Doudna, J.A.
Deposit date:2014-01-15
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Science, 343, 2014
2N62
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ddFLN5+110
Descriptor: gelation factor, secretion monitor chimera
Authors:Cabrita, L.D, Cassaignau, A.M.E, Launay, H.M.M, Waudby, C.A, Camilloni, C, Robertson, A.L, Wang, X, Wlodarski, T, Wentink, A.S, Vendruscolo, M, Dobson, C.M, Christodoulou, J.
Deposit date:2015-08-10
Release date:2016-03-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:A structural ensemble of a ribosome-nascent chain complex during cotranslational protein folding.
Nat.Struct.Mol.Biol., 23, 2016

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