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PDB: 153 件
6C8U
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Solution structure of Musashi2 RRM1
分子名称: RNA-binding protein Musashi homolog 2
著者Xing, M, Lan, L, Douglas, J.T, Gao, P, Hanzlik, R.P, Xu, L.
登録日2018-01-25
公開日2019-01-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1.
Proteins, 2019
3HOH
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RIBONUCLEASE T1 (THR93GLN MUTANT) COMPLEXED WITH 2'GMP
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1)
著者Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J.
登録日1998-09-11
公開日1998-09-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
7M5O
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Cryo-EM structure of CasPhi-2 (Cas12j) bound to crRNA
分子名称: CasPhi, ZINC ION, crRNA
著者Pausch, P, Soczek, K, Nogales, E, Doudna, J.
登録日2021-03-24
公開日2021-08-04
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献DNA interference states of the hypercompact CRISPR-Cas Phi effector.
Nat.Struct.Mol.Biol., 28, 2021
2OIH
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Hepatitis Delta Virus gemonic ribozyme precursor with C75U mutation and bound to monovalent cation Tl+
分子名称: HDV ribozyme, THALLIUM (I) ION, U1 small nuclear ribonucleoprotein A
著者Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A.
登録日2007-01-11
公開日2007-03-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
2OJ3
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Hepatitis Delta Virus ribozyme precursor structure, with C75U mutation, bound to Tl+ and cobalt hexammine (Co(NH3)63+)
分子名称: COBALT HEXAMMINE(III), HDV RIBOZYME, THALLIUM (I) ION, ...
著者Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A.
登録日2007-01-12
公開日2007-03-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
4HOH
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RIBONUCLEASE T1 (THR93ALA MUTANT) COMPLEXED WITH 2'GMP
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1)
著者Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J.
登録日1998-09-14
公開日1998-09-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
1VC5
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Crystal Structure of the Wild Type Hepatitis Delta Virus Gemonic Ribozyme Precursor, in EDTA solution
分子名称: Hepatitis Delta virus ribozyme, SODIUM ION, U1 small nuclear ribonucleoprotein A
著者Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
登録日2004-03-04
公開日2004-05-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VBZ
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Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Ba2+ solution
分子名称: BARIUM ION, Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A
著者Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
登録日2004-03-03
公開日2004-05-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1ZKM
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Structural Analysis of Escherichia Coli ThiF
分子名称: Adenylyltransferase thiF, ZINC ION
著者Duda, D.M, Walden, H, Sfondouris, J, Schulman, B.A.
登録日2005-05-03
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural Analysis of Escherichia Coli ThiF.
J.Mol.Biol., 349, 2005
1SJF
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Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Cobalt Hexammine solution
分子名称: COBALT HEXAMMINE(III), Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A
著者Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
登録日2004-03-03
公開日2004-05-18
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A conformational switch controls hepatitis delta virus ribozyme catalysis.
Nature, 429, 2004
1SJ4
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Crystal structure of a C75U mutant Hepatitis Delta Virus ribozyme precursor, in Cu2+ solution
分子名称: precursor form of the Hepatitis Delta virus ribozyme, small nuclear ribonucleoprotein A
著者Ke, A, Zhou, K, Ding, F, Cate, J.H, Doudna, J.A.
登録日2004-03-02
公開日2004-05-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A Conformational Switch controls hepatitis delta virus ribozyme catalysis
Nature, 429, 2004
3T4B
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Crystal Structure of the HCV IRES pseudoknot domain
分子名称: HCV IRES pseudoknot domain plus crystallization module, NICKEL (II) ION
著者Berry, K.E, Waghray, S, Mortimer, S.A, Bai, Y, Doudna, J.A.
登録日2011-07-25
公開日2011-10-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Crystal structure of the HCV IRES central domain reveals strategy for start-codon positioning.
Structure, 19, 2011
4AL5
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Crystal structure of the Csy4-crRNA product complex
分子名称: 5'-R(*UP*UP*CP*AP*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP *GP*GP*CP*AP*GP*C)-3', CSY4 ENDORIBONUCLEASE, GLYCEROL
著者Haurwitz, R.E, Sternberg, S.H, Doudna, J.A.
登録日2012-03-02
公開日2012-06-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA.
Embo J., 31, 2012
1DUL
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STRUCTURE OF THE RIBONUCLEOPROTEIN CORE OF THE E. COLI SIGNAL RECOGNITION PARTICLE
分子名称: 4.5 S RNA DOMAIN IV, MAGNESIUM ION, POTASSIUM ION, ...
著者Batey, R.T, Rambo, R.P, Lucast, L, Rha, B, Doudna, J.A.
登録日2000-01-17
公開日2000-02-28
最終更新日2020-10-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the ribonucleoprotein core of the signal recognition particle.
Science, 287, 2000
4AL7
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Crystal structure of the Csy4-minimal crRNA complex
分子名称: 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*AP*G)-3', CSY4 ENDORIBONUCLEASE
著者Haurwitz, R.E, Sternberg, S.H, Doudna, J.A.
登録日2012-03-02
公開日2012-06-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA.
Embo J., 31, 2012
4AL6
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Crystal structure of the S148ACsy4-crRNA complex
分子名称: CRRNA, 5'-R(CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP* CP*AP*GP*C)-3', CSY4 ENDORIBONUCLEASE
著者Haurwitz, R.E, Sternberg, S.H, Doudna, J.A.
登録日2012-03-02
公開日2012-06-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA.
Embo J., 31, 2012
1SJ3
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Hepatitis Delta Virus Gemonic Ribozyme Precursor, with Mg2+ Bound
分子名称: MAGNESIUM ION, precursor form of the Hepatitis Delta virus ribozyme, small nuclear ribonucleoprotein A
著者Ke, A, Zhou, K, Ding, F, Cate, J.H, Doudna, J.A.
登録日2004-03-02
公開日2004-05-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A Conformational Switch controls hepatitis delta virus ribozyme catalysis
Nature, 429, 2004
1RPC
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SOLUTION STRUCTURE OF RP 71955, A NEW 21 AMINO ACID TRICYCLIC PEPTIDE ACTIVE AGAINST HIV-1 VIRUS
分子名称: Tricyclic peptide RP 71955
著者Frechet, D, Guitton, J.D, Herman, F, Faucher, D, Helynck, G, Monegier Du Sorbier, B, Ridoux, J.P, James-Surcouf, E, Vuilhorgne, M.
登録日1993-08-31
公開日1994-01-31
最終更新日2024-06-05
実験手法SOLUTION NMR
主引用文献Solution structure of RP 71955, a new 21 amino acid tricyclic peptide active against HIV-1 virus.
Biochemistry, 33, 1994
1RPB
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SOLUTION STRUCTURE OF RP 71955, A NEW 21 AMINO ACID TRICYCLIC PEPTIDE ACTIVE AGAINST HIV-1 VIRUS
分子名称: Tricyclic peptide RP 71955
著者Frechet, D, Guitton, J.D, Herman, F, Faucher, D, Helynck, G, Monegier Du Sorbier, B, Ridoux, J.P, James-Surcouf, E, Vuilhorgne, M.
登録日1993-08-31
公開日1994-01-31
最終更新日2024-06-05
実験手法SOLUTION NMR
主引用文献Solution structure of RP 71955, a new 21 amino acid tricyclic peptide active against HIV-1 virus.
Biochemistry, 33, 1994
2X04
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Crystal structure of the PABC-TNRC6C complex
分子名称: POLYADENYLATE-BINDING PROTEIN 1, SULFATE ION, TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN
著者Jinek, M, Fabian, M.R, Coyle, S.M, Sonenberg, N, Doudna, J.A.
登録日2009-12-04
公開日2010-01-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structural Insights Into the Human Gw182-Pabc Interaction in Microrna-Mediated Deadenylation
Nat.Struct.Mol.Biol., 17, 2010
1VBY
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Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, and Mn2+ bound
分子名称: Hepatitis Delta virus ribozyme, MANGANESE (II) ION, SODIUM ION, ...
著者Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
登録日2004-03-03
公開日2004-05-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC0
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Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Imidazole and Sr2+ solution
分子名称: Hepatitis Delta virus ribozyme, STRONTIUM ION, U1 small nuclear ribonucleoprotein A
著者Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
登録日2004-03-03
公開日2004-05-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC6
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Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Product with C75U Mutaion, cleaved in Imidazole and Mg2+ solutions
分子名称: Hepatitis Delta virus ribozyme, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A
著者Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
登録日2004-03-04
公開日2004-05-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VBX
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Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in EDTA solution
分子名称: Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A
著者Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
登録日2004-03-03
公開日2004-05-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
3P3F
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Crystal structure of the F36A mutant of the fluoroacetyl-CoA-specific thioesterase FlK
分子名称: Fluoroacetyl coenzyme A thioesterase
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-04
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010

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