4KNX
 
 | | Hin GlmU Bound to WG176 | | 分子名称: | Bifunctional protein GlmU, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Doig, P, Kazmirski, S.L, Boriack-Sjodin, P.A. | | 登録日 | 2013-05-10 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Bioorg.Med.Chem., 22, 2014
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4KNR
 | | Hin GlmU bound to WG188 | | 分子名称: | Bifunctional protein GlmU, MAGNESIUM ION, N-{4-[(2-benzyl-7-hydroxy-6-methoxyquinazolin-4-yl)amino]phenyl}benzamide, ... | | 著者 | Doig, P, Kazmirski, S.L, Boriack-Sjodin, P.A. | | 登録日 | 2013-05-10 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Bioorg.Med.Chem., 22, 2014
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4KPZ
 | | Hin GlmU bound to a small molecule fragment | | 分子名称: | 1-(3-nitrophenyl)dihydropyrimidine-2,4(1H,3H)-dione, Bifunctional protein GlmU, MAGNESIUM ION, ... | | 著者 | Doig, P, Kazmirski, S.L, Boriack-Sjodin, P.A. | | 登録日 | 2013-05-14 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Bioorg.Med.Chem., 22, 2014
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4KPX
 | | Hin GlmU bound to WG766 | | 分子名称: | Bifunctional protein GlmU, MAGNESIUM ION, N-{4-[(4-hydroxy-3-nitrobenzoyl)amino]phenyl}pyridine-2-carboxamide, ... | | 著者 | Doig, P, Kazmirski, S.L, Boriack-Sjodin, P.A. | | 登録日 | 2013-05-14 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Bioorg.Med.Chem., 22, 2014
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4KQL
 | | Hin GlmU bound to WG578 | | 分子名称: | Bifunctional protein GlmU, MAGNESIUM ION, N-(4-{[3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-5-methoxybenzoyl]amino}phenyl)pyridine-2-carboxamide, ... | | 著者 | Doig, P, Kazmirski, S.L, Boriack-Sjodin, P.A. | | 登録日 | 2013-05-15 | | 公開日 | 2014-10-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping.
Bioorg.Med.Chem., 22, 2014
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2VVT
 | | Glutamate Racemase (MurI) from E. faecalis in complex with a 9-Benzyl Purine inhibitor | | 分子名称: | 2-butoxy-9-(2,6-difluorobenzyl)-N-(2-morpholin-4-ylethyl)-9H-purin-6-amine, D-GLUTAMIC ACID, GLUTAMATE RACEMASE | | 著者 | Geng, B, Breault, G, Comita-Prevoir, J, Petrichko, R, Eyermann, C, Lundqvist, T, Doig, P, Gorseth, E, Noonan, B. | | 登録日 | 2008-06-11 | | 公開日 | 2008-06-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Exploring 9-Benzyl Purines as Inhibitors of Glutamate Racemase (Muri) in Gram-Positive Bacteria.
Bioorg.Med.Chem.Lett., 18, 2008
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4E1K
 | | GlmU in complex with a Quinazoline Compound | | 分子名称: | Bifunctional protein GlmU, N-{4-[(7-hydroxy-6-methoxyquinazolin-4-yl)amino]phenyl}benzamide, SULFATE ION, ... | | 著者 | Larsen, N.A, Doig, P. | | 登録日 | 2012-03-06 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | An aminoquinazoline inhibitor of the essential bacterial cell wall synthetic enzyme GlmU has a unique non-protein-kinase-like binding mode.
Biochem.J., 446, 2012
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