4KQL

Hin GlmU bound to WG578

Summary for 4KQL

Entry DOI	10.2210/pdb4kql/pdb
Related	4KNR 4KNX 4KPX 4KPZ
Descriptor	Bifunctional protein GlmU, SULFATE ION, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	beta helix, cell wall biosynthesis, small molecule fragment, transferase
Biological source	Haemophilus influenzae
Cellular location	Cytoplasm : P43889
Total number of polymer chains	1
Total formula weight	50816.94
Authors	Doig, P.,Kazmirski, S.L.,Boriack-Sjodin, P.A. (deposition date: 2013-05-15, release date: 2014-10-15, Last modification date: 2024-02-28)
Primary citation	Doig, P.,Boriack-Sjodin, P.A.,Dumas, J.,Hu, J.,Itoh, K.,Johnson, K.,Kazmirski, S.,Kinoshita, T.,Kuroda, S.,Sato, T.O.,Sugimoto, K.,Tohyama, K.,Aoi, H.,Wakamatsu, K.,Wang, H. Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping. Bioorg.Med.Chem., 22:6256-6269, 2014 Cited by PubMed: 25262942 DOI: 10.1016/j.bmc.2014.08.017 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.31 Å)

Structure validation