6N2A
 
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7MFN
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7MFS
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7MQT
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6N2F
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4I7W
 | | Agrobacterium tumefaciens DHDPS with lysine and pyruvate | | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, LYSINE | | Authors: | Atkinson, S.C, Dogovski, C, Dobson, R.C.J, Perugini, M.A. | | Deposit date: | 2012-12-01 | | Release date: | 2013-12-04 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structure, function and allostery of the bona fide DHDPS from the plant pathogen Agrobacterium tumefaciens
To be Published
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4I7V
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4I7U
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4IK0
 | | Crystal structure of diaminopimelate epimerase Y268A mutant from Escherichia coli | | Descriptor: | Diaminopimelate epimerase, IODIDE ION | | Authors: | Hor, L, Dobson, R.C.J, Hutton, C.A, Perugini, M.A. | | Deposit date: | 2012-12-24 | | Release date: | 2013-02-20 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Dimerization of bacterial diaminopimelate epimerase is essential for catalysis
J.Biol.Chem., 288, 2013
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4GRS
 | | Crystal structure of a chimeric DAH7PS | | Descriptor: | Phospho-2-dehydro-3-deoxyheptonate aldolase, 2-dehydro-3-deoxyphosphoheptonate aldolase, TYROSINE | | Authors: | Cross, P.J, Allison, T.M, Dobson, R.C.J, Jameson, G.B, Parker, E.J. | | Deposit date: | 2012-08-26 | | Release date: | 2013-02-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain
Proc.Natl.Acad.Sci.USA, 110, 2013
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4IJZ
 | | Crystal structure of diaminopimelate epimerase from Escherichia coli | | Descriptor: | Diaminopimelate epimerase, NITRATE ION | | Authors: | Hor, L, Dobson, R.C.J, Hutton, C.A, Perugini, M.A. | | Deposit date: | 2012-12-24 | | Release date: | 2013-02-20 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Dimerization of bacterial diaminopimelate epimerase is essential for catalysis
J.Biol.Chem., 288, 2013
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2OJP
 | | The crystal structure of a dimeric mutant of Dihydrodipicolinate synthase from E.coli- DHDPS-L197Y | | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL | | Authors: | Griffin, M.D.W, Dobson, R.C.J, Antonio, L, Perugini, M.A, Jameson, G.B, Gerrard, J.A. | | Deposit date: | 2007-01-13 | | Release date: | 2008-01-01 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Evolution of quaternary structure in a homotetrameric enzyme.
J.Mol.Biol., 380, 2008
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3HIJ
 | | Crystal structure of dihydrodipicolinate synthase from Bacillus anthracis in complex with its substrate, pyruvate | | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, SODIUM ION | | Authors: | Voss, J.E, Scally, S.W, Dobson, R.C.J, Perugini, M.A. | | Deposit date: | 2009-05-20 | | Release date: | 2009-11-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax.
J.Biol.Chem., 285, 2010
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4YNG
 | | Twinned pyruvate kinase from E. coli in the T-state | | Descriptor: | Pyruvate kinase I, SULFATE ION | | Authors: | Donovan, K.A, Dobson, R.C.J. | | Deposit date: | 2015-03-10 | | Release date: | 2015-03-25 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Grappling with anisotropic data, pseudo-merohedral twinning and pseudo-translational noncrystallographic symmetry: a case study involving pyruvate kinase.
Acta Crystallogr D Struct Biol, 72, 2016
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7LOY
 | | Dihydrodipicolinate synthase with pyruvate from Candidatus Liberibacter solanacearum | | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase | | Authors: | Gilkes, J.M, Frampton, R.A, Board, A, Sheen, C.R, Smith, G.R, Dobson, R.C.J. | | Deposit date: | 2021-02-11 | | Release date: | 2021-03-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Dihydrodipicolinate synthase with pyruvate from the plant pathogen, Candidatus Liberibacter solanacearum
To Be Published
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4C1L
 | | Crystal structure of pyrococcus furiosus 3-deoxy-D-arabino- heptulosonate 7-phosphate synthase I181D interface mutant | | Descriptor: | 2-dehydro-3-deoxyphosphoheptonate aldolase, CHLORIDE ION, MANGANESE (II) ION, ... | | Authors: | Nazmi, A.R, Schofield, L.R, Dobson, R.C.J, Jameson, G.B, Parker, E.J. | | Deposit date: | 2013-08-13 | | Release date: | 2013-11-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Destabilization of the homotetrameric assembly of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from the hyperthermophile Pyrococcus furiosus enhances enzymatic activity.
J. Mol. Biol., 426, 2014
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4EOU
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4WAA
 | | Crystal structure of Nix LIR-fused human LC3B_2-119 | | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B | | Authors: | Suzuki, H, Ravichandran, A.C, Dobson, R.C.J, Novak, I, Wakatsuki, S. | | Deposit date: | 2014-08-29 | | Release date: | 2015-09-09 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins.
Sci Rep, 7, 2017
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3WAO
 | | Crystal structure of Atg13 LIR-fused human LC3B_2-119 | | Descriptor: | Autophagy-related protein 13, Microtubule-associated proteins 1A/1B light chain 3B | | Authors: | Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S. | | Deposit date: | 2013-05-06 | | Release date: | 2013-12-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.
Structure, 22, 2014
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3WAN
 | | Crystal structure of Atg13 LIR-fused human LC3A_2-121 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Autophagy-related protein 13, Microtubule-associated proteins 1A/1B light chain 3A | | Authors: | Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S. | | Deposit date: | 2013-05-06 | | Release date: | 2013-12-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.
Structure, 22, 2014
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3WAM
 | | Crystal structure of human LC3C_8-125 | | Descriptor: | CITRIC ACID, Microtubule-associated proteins 1A/1B light chain 3C | | Authors: | Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S. | | Deposit date: | 2013-05-06 | | Release date: | 2013-12-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.
Structure, 22, 2014
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3WAP
 | | Crystal structure of Atg13 LIR-fused human LC3C_8-125 | | Descriptor: | Autophagy-related protein 13, Microtubule-associated proteins 1A/1B light chain 3C | | Authors: | Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S. | | Deposit date: | 2013-05-06 | | Release date: | 2013-12-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.
Structure, 22, 2014
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3WAL
 | | Crystal structure of human LC3A_2-121 | | Descriptor: | D-MALATE, Microtubule-associated proteins 1A/1B light chain 3A | | Authors: | Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S. | | Deposit date: | 2013-05-06 | | Release date: | 2013-12-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.
Structure, 22, 2014
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7JZD
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7JZE
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